PhD Ana Rey Rico  

Investigadora contratada no programa Ramón y Cajal (PR-RC)

Research  Research group Nanochemistry and Self-Assembly for Biological Sciences
Research lines No data available from Curriculum Management System at UDC. (SUXI).
Contacto UDC directory
Orcid id0000-0003-1682-498X ResearcherIDK-5951-2014 Scopus36136260600

Teaching

Subjects taught

This section shows the teaching given in degrees, masters and other officers studies in last 6 years.

Subject and involved studies Distance hours Total hours
Final Year Dissertation
Concurrent Programme of Studies for Degree in Biology and Degree in Chemistry
Degree in Biology
0 3
Master's Dissertation
Master's in Molecular Cellular and Genetic Biology
0 8
Subject and involved studies Distance hours Total hours
Biology: Basic Levels of Organisation of Life I (Cells) 0 63
Subject and involved studies Distance hours Total hours
Biology: Basic Levels of Organisation of Life I (Cells)
Concurrent Programme of Studies for Degree in Biology and Degree in Chemistry
Degree in Biology
0 55
Final Year Dissertation
Concurrent Programme of Studies for Degree in Biology and Degree in Chemistry
Degree in Biology
0 9
Master's Dissertation
Master's in Molecular Cellular and Genetic Biology
0 0
Master's Dissertation
Master's in Advanced Biotechnology
0 8
Subject and involved studies Distance hours Total hours
Biological Basis and Physical Human Movement
Degree in Podiatry
0 16
Biology: Basic Levels of Organisation of Life I (Cells)
Concurrent Programme of Studies for Degree in Biology and Degree in Chemistry
Degree in Biology
0 48
Final Year Dissertation
Concurrent Programme of Studies for Degree in Biology and Degree in Chemistry
Degree in Biology
0 12
Master's Dissertation
Master's in Molecular Cellular and Genetic Biology
0 4
Subject and involved studies Distance hours Total hours
Biological Basis and Physical Human Movement
Degree in Podiatry
0 16
Biology: Basic Levels of Organisation of Life I (Cells)
Concurrent Programme of Studies for Degree in Biology and Degree in Chemistry
Degree in Biology
0 58
Final Year Dissertation
Concurrent Programme of Studies for Degree in Biology and Degree in Chemistry
Degree in Biology
0 6
Subject and involved studies Distance hours Total hours
Anatomy and Kinetics of Human Movement
Degree in Sports Science and Physical Activity
0 20
Anatomy I and Histology
Degree in Physiotherapy
0 9
Application of Research Techniques in Health Sciences
Master`s Degree in Health Care and Research
0 6
Cell Culture Techniques
Master`s Degree in Health Care and Research
0 8.5
Handling and Analysis Techniques for Nucleic Acids
Master`s Degree in Health Care and Research
0 20

Defined tutoring by teacher for 2023/2024 academic course.

Faculty of Science

Quarter Day Site
1st quarter Thursday
10:00 a 14:00
Laboratorio de Biología celular. Contactar previamente por email: ana.rey.rico@udc.es

EOG works and final master thesis directed

Directed or codirected by current teacher since 2013 year.

Development of new non-viral systems for genetic modification in senescent cells
Genetic modification of mesenchymal stem cells via hydrazone-activated polymers
Non-viral systems based on niosomes as new tools for senescent cells gene transfer
Biological analysis of viologen derivatives targeted to mitochondria
Gene transfer systems for the effective transfection of mesenchymal stem cells
Gene transfer systems for the effective transfection of mesenchymal stem cells
Genetic modification of mesenchymal stem cells with non-viral vectors.
Preliminary screening of the biomedical potential from organic nanocontainers.
Cell penetrating peptides-based gene delivery systems for the effective transfection of mesenchymal stem cells
Gene delivery systems for the effective transfection of mesenchymal stem cells

Research results

Select merit type and year to query research merits.

AYUDAS PARA LA CONSOLIDACIÓN Y ESTRUTURACIÓN DE UNIDADES DE INVESTIGACIÓN COMPETITIVAS. GPC 2023

Funding entity Consellería de Cultura, Educación e Ordenación Universitaria
Main researches Francisco Fernández Trillo
Type Proyecto Programas Autonomicos
Dates From 01/01/2023 to 20/11/2025

Polímeros Helicoidales para la Liberación de Genes en Células Madre Mesenquimales

Funding entity Ministerio de Ciencia e Innovación
Main researches Fernández Trillo, Francisco (IP1),Rey Rico, Ana (IP2)
Type Proyecto Programas Nacionales
Dates From 01/09/2022 to 31/08/2025

AXUDAS PARA A CONSOLIDACIÓN E ESTRUTURACIÓN DE UNIDADES DE INVESTIGACIÓN COMPETITIVAS.EXCELENCIA 2021

Funding entity Consellería de Cultura, Educación e Ordenación Universitaria
Main researches Ana Rey Rico
Type Proyecto Programas Autonomicos
Dates From 01/01/2021 to 20/11/2025

Axudas para a consolidación e estruturación de unidades de investigación competitivas-GPC

Funding entity Consellería de Educación e Ordenación Universitaria
Main researches Díaz Pardo, Silvia
Type Proyecto Programas Autonomicos
Dates From 01/01/2020 to 31/12/2023

Criogeles activados por genes para reparación de cartílago

Funding entity Ministerio de Ciencia, Innovación y Universidades
Main researches Ana Rey Rico
Type Proyecto Programas Nacionales
Dates From 01/01/2019 to 31/12/2021

Mechanisms of self-assembly temperature-sensitive polymers for enhanced rAAV-mediated gene transfer into human mesenchymal stem cells

Funding entity DFG ( Deutsche Forschungsgemeinschaft)
Main researches Ana Rey Rico
Type Proyecto Programas Nacionales
Dates From 01/01/2016 to 31/12/2017

Homburger Forschungsförderungsprogramm HOMFOR: Mejor proyecto de investigación Facultad de Medicina, Universidad de Saarland

Funding entity Center of Experimental Orthopaedics, Saarland University Medical Center
Main researches Ana Rey Rico, Magali Cucchiarini, Henning Madry
Type Proyecto Otros Programas
Dates From 01/01/2015 to 31/12/2015

"Vermellogens" and the Development of CB[8]-Based Supramolecular Switches Using pH-Responsive and Non-Toxic Viologen Analogues

Authors Liliana Barravecchia, Arturo Blanco-Gómez, Iago Neira, Raminta Skackauskaite, Alejandro Vila, Rey-Rico, A, Carlos Peinador, Marcos D. García
Journal JOURNAL OF THE AMERICAN CHEMICAL SOCIETY Vol. 144 (pages 19127 to 19136)
DOI https://doi.org/10.1021/jacs.2c08575

Chondrogenic Differentiation of Human Mesenchymal Stem Cells via SOX9 Delivery in Cationic Niosomes

Authors Carballo-Pedrares, Natalia, Sanjurjo-Rodriguez, Clara, Senaris, Jose, Diaz-Prado, Silvia, Rey-Rico, Ana
Journal PHARMACEUTICS Vol. 14 Num. 11
DOI https://doi.org/10.3390/pharmaceutics14112327

pNaSS-Grafted PCL Film-Guided rAAV TGF-beta Gene Therapy Activates the Chondrogenic Activities in Human Bone Marrow Aspirates.

Authors Venkatesan, Jagadeesh K, Cai, Xiaoyu, Meng, Weikun, Rey-Rico, Ana, Schmitt, Gertrud, Speicher-Mentges, Susanne, Falentin-Daudre, Celine, Leroux, Amelie, Madry, Henning, Migonney, Veronique, Cucchiarini, Magali
Journal Human gene therapy
DOI https://doi.org/10.1089/hum.2020.329

Hydrogel-Guided, rAAV-Mediated IGF-I Overexpression Enables Long-Term Cartilage Repair and Protection against Perifocal Osteoarthritis in a Large-Animal Full-Thickness Chondral Defect Model at One Year In Vivo

Authors Maihofer, J, Madry, H, Rey-Rico, A, Venkatesan, JK, Goebel, L, Schmitt, G, Speicher-Mentges, S, Cai, XY, Meng, WK, Zurakowski, D, Menger, MD, Laschke, MW, Cucchiarini, M
Journal ADVANCED MATERIALS Vol. 33 Num. 16
DOI https://doi.org/10.1002/adma.202008451

Biomaterial-assisted gene therapy for translational approaches to treat musculoskeletal disorders

Authors Venkatesan, JK, Rey-Rico, A, Meng, W, Cai, X, Pons, F, Lebeau, L, Migonney, V, Madry, H, Cucchiarini, M
Journal MATERIALS TODAY ADVANCES Vol. 9
DOI https://doi.org/10.1016/j.mtadv.2020.100126

Niosomes-based gene delivery systems for effective transfection of human mesenchymal stem cells

Authors Carballo-Pedrares, Natalia, Kattar, Axel, Concheiro, Angel, Alvarez-Lorenzo, Carmen, Rey-Rico, Ana
Journal MATERIALS SCIENCE AND ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS Vol. 128
DOI https://doi.org/10.1016/j.msec.2021.112307

Recent Progress on Polysaccharide-Based Hydrogels for Controlled Delivery of Therapeutic Biomolecules

Authors Rial-Hermida, M. Isabel, Rey-Rico, Ana, Blanco-Fernandez, Barbara, Carballo-Pedrares, Natalia, Byrne, Eimear M., Mano, Joao F.
Journal ACS BIOMATERIALS SCIENCE & ENGINEERING Vol. 7 Num. 9 (pages 4102 to 4127)
DOI https://doi.org/10.1021/acsbiomaterials.0c01784

Thermosensitive Hydrogel Based on PEO-PPO-PEO Poloxamers for a Controlled In Situ Release of Recombinant Adeno-Associated Viral Vectors for Effective Gene Therapy of Cartilage Defects

Authors Madry, H, Gao, L, Rey-Rico, A, Venkatesan, JK, Muller-Brandt, K, Cai, XY, Goebel, L, Schmitt, G, Speicher-Mentges, S, Zurakowski, D, Menger, MD, Laschke, MW, Cucchiarini, M
Journal ADVANCED MATERIALS Vol. 32 Num. 2
DOI https://doi.org/10.1002/adma.201906508

Scaffold-Mediated Gene Delivery for Osteochondral Repair

Authors Madry, H, Venkatesan, JK, Carballo-Pedrares, N, Rey-Rico, A, Cucchiarini, M
Journal PHARMACEUTICS Vol. 12 Num. 10
DOI https://doi.org/10.3390/pharmaceutics12100930

Hydrogel-Based Localized Nonviral Gene Delivery in Regenerative Medicine Approaches-An Overview

Authors Carballo-Pedrares, N, Fuentes-Boquete, I, Diaz-Prado, S, Rey-Rico, A
Journal PHARMACEUTICS Vol. 12 Num. 8
DOI https://doi.org/10.3390/pharmaceutics12080752

Therapeutic Delivery of rAAV sox9 via Polymeric Micelles Counteracts the Effects of Osteoarthritis-Associated Inflammatory Cytokines in Human Articular Chondrocytes

Authors Urich, J, Cucchiarini, M, Rey-Rico, A
Journal Nanomaterials Vol. 10 Num. 6
DOI https://doi.org/10.3390/nano10061238

rAAV-Mediated Overexpression of SOX9 and TGF-beta via Carbon Dot-Guided Vector Delivery Enhances the Biological Activities in Human Bone Marrow-Derived Mesenchymal Stromal Cells

Authors Meng, WK, Rey-Rico, A, Claudel, M, Schmitt, G, Speicher-Mentges, S, Pons, F, Lebeau, L, Venkatesan, JK, Cucchiarini, M
Journal Nanomaterials Vol. 10 Num. 5
DOI https://doi.org/10.3390/nano10050855

Controlled Release of rAAV Vectors from APMA-Functionalized Contact Lenses for Corneal Gene Therapy

Authors Alvarez-Rivera, F, Rey-Rico, A, Venkatesan, JK, Diaz-Gomez, L, Cucchiarini, M, Concheiro, A, Alvarez-Lorenzo, C
Journal PHARMACEUTICS Vol. 12 Num. 4
DOI https://doi.org/10.3390/pharmaceutics12040335

Enhanced Chondrogenic Differentiation Activities in Human Bone Marrow Aspirates via sox9 Overexpression Mediated by pNaSS-Grafted PCL Film-Guided rAAV Gene Transfer

Authors Venkatesan, JK, Meng, WK, Rey-Rico, A, Schmitt, G, Speicher-Mentges, S, Falentin-Daudre, C, Leroux, A, Madry, H, Migonney, V, Cucchiarini, M
Journal PHARMACEUTICS Vol. 12 Num. 3
DOI https://doi.org/10.3390/pharmaceutics12030280

Current Trends in Viral Gene Therapy for Human Orthopaedic Regenerative Medicine

Authors Jagadeesh Kumar Venkatesan, Rey-Rico, A, Magali Cucchiarini
Journal Tissue Engineering and Regenerative Medicine (pages 1 to 11)
DOI https://doi.org/10.1007/s13770-019-00179-x

Remodeling of Human Osteochondral Defects via rAAV-Mediated Co-Overexpression of TGF-beta and IGF-I from Implanted Human Bone Marrow-Derived Mesenchymal Stromal Cells.

Authors Morscheid, Stephanie, Venkatesan, Jagadeesh Kumar, Rey-Rico, Ana, Schmitt, Gertrud, Cucchiarini, Magali
Journal JOURNAL OF CLINICAL MEDICINE Vol. 8 Num. 9
DOI https://doi.org/10.3390/jcm8091326

Therapeutic Effects of rAAV-Mediated Concomittant Gene Transfer and Overexpression of TGF- and IGF-I on the Chondrogenesis of Human Bone-Marrow-Derived Mesenchymal Stem Cells

Authors Morscheid, S, Rey-Rico, A, Schmitt, G, Madry, H, Cucchiarini, M, Venkatesan, JK
Journal International Journal of Molecular Sciences Vol. 20 Num. 10
DOI https://doi.org/10.3390/ijms20102591

Effects of rAAV-Mediated sox9 Overexpression on the Biological Activities of Human Osteoarthritic Articular Chondrocytes in Their Intrinsic Three-Dimensional Environment

Authors Daniels, Oliver, Frisch, Janina, Venkatesan, Jagadeesh K., Rey-Rico, Ana, Schmitt, Gertrud, Cucchiarini, Magali
Journal JOURNAL OF CLINICAL MEDICINE Vol. 8 Num. 10
DOI https://doi.org/10.3390/jcm8101637

PEO-PPO-PEO Tri-Block Copolymers for Gene Delivery Applications in Human Regenerative Medicine-An Overview

Authors Rey-Rico, A, Cucchiarini, M
Journal International Journal of Molecular Sciences Vol. 19 Num. 3
DOI https://doi.org/10.3390/ijms19030775

Effective Remodelling of Human Osteoarthritic Cartilage by sox9 Gene Transfer and Overexpression upon Delivery of rAAV Vectors in Polymeric Micelles

Authors Rey-Rico, A, Venkatesan, JK, Schmitt, G, Speicher-Mentges, S, Madry, H, Cucchiarini, M
Journal MOLECULAR PHARMACEUTICS Vol. 15 Num. 7 (pages 2816 to 2826)
DOI https://doi.org/10.1021/acs.molpharmaceut.8b00331

Chondrogenic Differentiation Processes in Human Bone-Marrow Aspirates Seeded in Three-Dimensional-Woven Poly(¿-Caprolactone) Scaffolds Enhanced by Recombinant Adeno-Associated Virus-Mediated SOX9 Gene Transfer

Authors Jagadeesh Kumar Venkatesan, FT Moutos, Rey-Rico, A, BT Estes, Janina Fisch, Gertrud Schmitt, Henning Madry, Guilak, F, Magali Cucchiarini
Journal HUMAN GENE THERAPY Vol. 29 Num. 11 (pages 1277 to 1286)
DOI https://doi.org/10.1089/hum.2017.165

Improved Chondrogenic Differentiation of rAAV SOX9-Modified Human MSCs Seeded in Fibrin-Polyurethane Scaffolds in a Hydrodynamic Environment

Authors Jagadeesh Kumar Venkatesan, Gardner, O, Rey-Rico, A, David Eglin, Mauro Alini, Martin Stoddart, Magali Cucchiarini, Henning Madry
Journal International Journal of Molecular Sciences
DOI https://doi.org/10.3390/ijms19092635

Antimicrobial Properties and Osteogenicity of Vancomycin-Loaded Synthetic Scaffolds Obtained by Supercritical Foaming

Authors Carlos García Gonzalez, Joana Barros, Rey-Rico, A, Pablo Redondo, Jose Luis Gómez Amoza, Concheiro, A, Carmen Alvarez Lorenzo, Fernando J Monteiro
Journal ACS APPLIED MATERIALS & INTERFACES Vol. 10 (pages 3349 to 3360)
DOI https://doi.org/10.1021/acsami.7b17375

Sustained spatiotemporal release of TGF-ß1 confers enhanced very early chondrogenic differentiation during osteochondral repair in specific topographic patterns

Authors Ann-Kathrin Asen, Lars Goebel, Rey-Rico, A, Jerome Sohier, Magali Cucchiarini, Henning Madry
Journal FASEB JOURNAL Vol. 32 (pages 5298 to 5311)
DOI https://doi.org/10.1096/fj.201800105r

rAAV-mediated overexpression of TGF-beta via vector delivery in polymeric micelles stimulates the biological and reparative activities of human articular chondrocytes in vitro and in a human osteochondral defect model

Authors Rey-Rico, A, Venkatesan, JK, Schmitt, G, Concheiro, A, Madry, H, Alvarez-Lorenzo, C, Cucchiarini, M
Journal INTERNATIONAL JOURNAL OF NANOMEDICINE Vol. 12 (pages 6985 to 6996)
DOI https://doi.org/10.2147/ijn.s144579

Supramolecular polypseudorotaxane gels for controlled delivery of rAAV vectors in human mesenchymal stem cells for regenerative medicine

Authors Rey-Rico, A, Babicz, H, Madry, H, Concheiro, A, Alvarez-Lorenzo, C, Cucchiarini, M
Journal INTERNATIONAL JOURNAL OF PHARMACEUTICS Vol. 531 Num. 2 (pages 492 to 503)
DOI https://doi.org/10.1016/j.ijpharm.2017.05.050

Peripheral blood aspirates overexpressing IGF-I via rAAV gene transfer undergo enhanced chondrogenic differentiation processes

Authors Frisch, J, Orth, P, Rey-Rico, A, Venkatesan, JK, Schmitt, G, Madry, H, Kohn, D, Cucchiarini, M
Journal JOURNAL OF CELLULAR AND MOLECULAR MEDICINE Vol. 21 Num. 11 (pages 2748 to 2758)
DOI https://doi.org/10.1111/jcmm.13190

Effects of combined rAAV-mediated TGF-beta and sox9 gene transfer and overexpression on the metabolic and chondrogenic activities in human bone marrow aspirates.

Authors Tao, Ke, Rey-Rico, A, Frisch, Janina, Venkatesan, Jagadeesh Kumar, Schmitt, Gertrud, Madry, Henning, Lin, Jianhao, Cucchiarini, Magali
Journal Journal of experimental orthopaedics Vol. 4 Num. 1
DOI https://doi.org/10.1186/s40634-017-0077-5

Impact of mechanical stimulation on the chondrogenic processes in human bone marrow aspirates modified to overexpress sox9 via rAAV vectors.

Authors Venkatesan, Jagadeesh K, Frisch, Janina, Rey-Rico, A, Schmitt, Gertrud, Madry, Henning, Cucchiarini, Magali
Journal Journal of experimental orthopaedics Vol. 4 Num. 1
DOI https://doi.org/10.1186/s40634-017-0097-1

Genetic Modification of Human Peripheral BloodAspirates Using Recombinant Adeno-Associated ViralVectors for Articular Cartilage Repair with a Focus onChondrogenic Transforming Growth Factor-bGene Delivery

Authors JANINA FRISCH, PATRIC KORTH, AGADEESH KUMAR VENKATESAN, Rey-Rico, A, GERTRUD SCHMITT, DIETER KOHN, HENNING MADRY,, MAGALI CUCCHIARINI
Journal STEM CELLS TRANSLATIONAL MEDICINE Vol. 6 Num. 1 (pages 249 to 260)
DOI https://doi.org/10.5966/sctm.2016-0149

Smart and Controllable rAAV Gene Delivery Carriers in Progenitor Cells for Human Musculoskeletal Regenerative Medicine with a Focus on the Articular Cartilage.

Authors Rey-Rico, A, Magali Cucchiarini
Journal Current Gene Therapy Vol. 17 Num. 2
DOI https://doi.org/10.2174/1566523217666170510162459

Hydrogels for precision meniscus tissue engineering: a comprehensive review.

Authors Rey-Rico, A, Cucchiarini M, Madry H
Journal CONNECTIVE TISSUE RESEARCH Vol. 58 Num. 3-4 (pages 317 to 328)
DOI https://doi.org/10.1080/03008207.2016.1276576.

Effects of rAAV-mediated FGF-2 gene transfer and overexpression upon the chondrogenic differentiation processes in human bone marrow aspirates.

Authors Frisch, Janina, Venkatesan, Jagadeesh K, Rey-Rico, A, Zawada, Adam M, Schmitt, Gertrud, Madry, Henning, Cucchiarini, Magali
Journal Journal of experimental orthopaedics Vol. 3 Num. 1
DOI https://doi.org/10.1186/s40634-016-0052-6

Biomedical-grade, high mannuronic acid content (BioMVM) alginate enhances the proteoglycan production of primary human meniscal fibrochondrocytes in a 3-D microenvironment

Authors Rey-Rico, A, Klich, A, Cucchiarini, M, Madry, H
Journal SCIENTIFIC REPORTS Vol. 6
DOI https://doi.org/10.1038/srep28170

TGF- gene transfer and overexpression via rAAV vectors stimulates chondrogenic events in human bone marrow aspirates

Authors Frisch, J, Rey-Rico, A, Venkatesan, JK, Schmitt, G, Madry, H, Cucchiarini, M
Journal JOURNAL OF CELLULAR AND MOLECULAR MEDICINE Vol. 20 Num. 3 (pages 430 to 440)
DOI https://doi.org/10.1111/jcmm.12774

rAAV-mediated combined gene transfer and overexpression of TGF- and SOX9 remodels human osteoarthritic articular cartilage

Authors Tao, K, Rey-Rico, A, Frisch, J, Venkatesan, JK, Schmitt, G, Madry, H, Lin, JH, Cucchiarini, M
Journal JOURNAL OF ORTHOPAEDIC RESEARCH Vol. 34 Num. 12 (pages 2181 to 2190)
DOI https://doi.org/10.1002/jor.23228

rAAV-mediated overexpression of sox9, TGF-beta and IGF-I in minipig bone marrow aspirates to enhance the chondrogenic processes for cartilage repair

Authors Frisch, J, Rey-Rico, A, Venkatesan, JK, Schmitt, G, Madry, H, Cucchiarini, M
Journal GENE THERAPY Vol. 23 Num. 3 (pages 247 to 255)
DOI https://doi.org/10.1038/gt.2015.106

Co-overexpression of TGF-beta and SOX9 via rAAV gene transfer modulates the metabolic and chondrogenic activities of human bone marrow-derived mesenchymal stem cells

Authors Tao, K, Frisch, J, Rey-Rico, A, Venkatesan, JK, Schmitt, G, Madry, H, Lin, JH, Cucchiarini, M
Journal Stem Cell Research & Therapy Vol. 7
DOI https://doi.org/10.1186/s13287-016-0280-9

Hydrogel-Based Controlled Delivery Systems for Articular Cartilage Repair

Authors Rey-Rico, A, Henning Madry, Magali Cucchiarini
Journal BioMed Research International
DOI https://doi.org/10.1155/2016/1215263

Recent tissue engineering-based advances for effective rAAV-mediated gene transfer in the musculoskeletal system

Authors Magali Cucchiarini, Rey-Rico, A
Journal Bioengineered Vol. 7 Num. 3
DOI https://doi.org/10.1080/21655979.2016.1187347

PEO-PPO-PEO Carriers for rAAV-Mediated Transduction of Human Articular Chondrocytes in Vitro and in a Human Osteochondral Defect Model

Authors Rey-Rico, Ana, Frisch, Janina, Venkatesan, Jagadesh Kumar, Schmitt, Gertrud, Rial-Hermida, Isabel, Taboada, Pablo, Concheiro, Angel, Madry, Henning, Alvarez-Lorenzo, Carmen, Cucchiarini, Magali
Journal ACS APPLIED MATERIALS & INTERFACES Vol. 8 Num. 32 (pages 20600 to 20613)
DOI https://doi.org/10.1021/acsami.6b06509

Effective genetic modification and differentiation of hMSCs upon controlled release of rAAV vectors using alginate/poloxamer composite systems

Authors Diaz-Rodriguez, P, Rey-Rico, A, Madry, H, Landin, M, Cucchiarini, M
Journal INTERNATIONAL JOURNAL OF PHARMACEUTICS Vol. 496 Num. 2 (pages 614 to 626)
DOI https://doi.org/10.1016/j.ijpharm.2015.11.008

PEO-PPO-PEO micelles as effective rAAV-mediated gene delivery systems to target human mesenchymal stem cells without altering their differentiation potency

Authors Rey-Rico, A, Venkatesan, JK, Frisch, J, Rial-Hermida, I, Schmitt, G, Concheiro, A, Madry, H, Alvarez-Lorenzo, C, Cucchiarini, M
Journal ACTA BIOMATERIALIA Vol. 27 (pages 42 to 52)
DOI https://doi.org/10.1016/j.actbio.2015.08.046

Chondrogenic Differentiation Processes in Human Bone Marrow Aspirates upon rAAV-Mediated Gene Transfer and Overexpression of the Insulin-Like Growth Factor I

Authors Frisch, J, Rey-Rico, A, Venkatesan, JK, Schmitt, G, Madry, H, Cucchiarini, M
Journal TISSUE ENGINEERING PART C-METHODS Vol. 21 (pages 2460 to 2471)
DOI https://doi.org/10.1089/ten.tea.2014.0679

Effective and durable genetic modification of human mesenchymal stem cells via controlled release of rAAV vectors from self-assembling peptide hydrogels with a maintained differentiation potency

Authors Rey-Rico, A, Venkatesan, JK, Frisch, J, Schmitt, G, Monge-Marcet, A, Lopez-Chicon, P, Mata, A, Semino, C, Madry, H, Cucchiarini, M
Journal ACTA BIOMATERIALIA Vol. 18 (pages 118 to 127)
DOI https://doi.org/10.1016/j.actbio.2015.02.013

Adapted chondrogenic differentiation of human mesenchymal stem cells via controlled release of TGF-beta 1 from poly(ethylene oxide)-terephtalate/poly(butylene terepthalate) multiblock scaffolds

Authors Rey-Rico, A, Venkatesan, JK, Sohier, J, Moroni, L, Cucchiarini, M, Madry, H
Journal JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A Vol. 103 Num. 1 (pages 371 to 383)
DOI https://doi.org/10.1002/jbm.a.35181

Determination of effective rAAV-mediated gene transfer conditions to support chondrogenic differentiation processes in human primary bone marrow aspirates

Authors Rey-Rico, A, Frisch, J, Venkatesan, JK, Schmitt, G, Madry, H, Cucchiarini, M
Journal GENE THERAPY Vol. 22 Num. 1 (pages 50 to 57)
DOI https://doi.org/10.1038/gt.2014.90

Supramolecular cyclodextrin-based drug nanocarriers

Authors Simões SM, Rey-Rico, A, Concheiro A, Alvarez-Lorenzo C.
Journal CHEM. COMMUN. Vol. 51 Num. 29 (pages 6275 to 6289)
DOI https://doi.org/10.1039/c4cc10388b

Determination of the Chondrogenic Differentiation Processes in Human Bone Marrow-Derived Mesenchymal Stem Cells Genetically Modified to Overexpress Transforming Growth Factor-beta via Recombinant Adeno-Associated Viral Vectors

Authors Frisch, J, Venkatesan, JK, Rey-Rico, A, Schmitt, G, Madry, H, Cucchiarini, M
Journal HUMAN GENE THERAPY Vol. 25 Num. 12 (pages 1050 to 1060)
DOI https://doi.org/10.1089/hum.2014.091

Nonviral gene transfer into human meniscal cells. Part II: effect of three-dimensional environment and overexpression of human fibroblast growth factor 2

Authors Lee, HP, Rey-Rico, A, Cucchiarini, M, Madry, H
Journal INTERNATIONAL ORTHOPAEDICS Vol. 38 Num. 9 (pages 1931 to 1936)
DOI https://doi.org/10.1007/s00264-014-2405-z

Influence of insulin-like growth factor I overexpression via recombinant adeno-associated vector gene transfer upon the biological activities and differentiation potential of human bone marrow-derived mesenchymal stem cells

Authors Frisch, J, Venkatesan, JK, Rey-Rico, A, Schmitt, G, Madry, H, Cucchiarini, M
Journal Stem Cell Research & Therapy Vol. 5
DOI https://doi.org/10.1186/scrt491

Current progress in stem cell-based gene therapy for articular cartilage repair.

Authors Janina Frisch, Jagadeesh K Venkatesan, Rey-Rico, A, Henning Madry, Magali Cucchiarini
Journal Current Stem Cell Research & Therapy Vol. 10 Num. 2
DOI https://doi.org/10.2174/1574888x09666140922112326

Transforming growth factor Beta-releasing scaffolds for cartilage tissue engineering.

Authors Madry H, Rey-Rico, A, Venkatesan, JK, Johnstone B, Cucchiarini M.
Journal Tissue Engineering Part B: Reviews Vol. 20 Num. 2 (pages 106 to 125)
DOI https://doi.org/10.1089/ten.teb.2013.0271

Current perspectives in stem cell research for knee cartilage repair.

Authors Patrick Orth, Rey-Rico, A, Jagadeesh K Venkatesan, Henning Madry, Magali Cucchiarini
Journal Stem Cells and Cloning Vol. 7 (pages 1 to 17)
DOI https://doi.org/10.2147/sccaa.s42880

Poly(styrene oxide)-poly(ethylene oxide) block copolymers: From ¿classical¿ chemotherapeutic nanocarriers to active cell-response inducers

Authors A. Cambón, Rey-Rico, A, S. Barbosa, J.F.A. Soltero, S.G. Yeates, J. Brea, M.I. Loza, C. Alvarez-Lorenzo, A. Concheiro, Taboada, P, V. Mosquera
Journal JOURNAL OF CONTROLLED RELEASE Vol. 167 Num. 1 (pages 68 to 75)
DOI https://doi.org/10.1016/j.jconrel.2013.01.010

Doxorubicin-loaded micelles of reverse poly(butylene oxide)-poly(ethylene oxide)-poly(butylene oxide) block copolymers as efficient "active" chemotherapeutic agents

Authors Cambon, A, Rey-Rico, A, Mistry, D, Brea, J, Loza, MI, Attwood, D, Barbosa, S, Alvarez-Lorenzo, C, Concheiro, A, Taboada, P, Mosquera, V
Journal INTERNATIONAL JOURNAL OF PHARMACEUTICS Vol. 445 Num. 1-2 (pages 47 to 57)
DOI https://doi.org/10.1016/j.ijpharm.2013.01.056

rAAV-mediated overexpression of TGF-beta stably restructures human osteoarthritic articular cartilage in situ

Authors Venkatesan, JK, Rey-Rico, A, Schmitt, G, Wezel, A, Madry, H, Cucchiarini, M
Journal JOURNAL OF TRANSLATIONAL MEDICINE Vol. 11 (pages 211 to 211)
DOI https://doi.org/10.1186/1479-5876-11-211

Poly(ethylene oxide)-poly(styrene oxide)-poly(ethylene oxide) copolymers: Micellization, drug solubilization, and gelling features

Authors Cambon, A, Barbosa, S, Rey-Rico, A, Figueroa-Ochoa, EB, Soltero, JFA, Yeates, SG, Alvarez-Lorenzo, C, Concheiro, A, Taboada, P, Mosquera, V
Journal JOURNAL OF COLLOID AND INTERFACE SCIENCE Vol. 387 (pages 275 to 284)
DOI https://doi.org/10.1016/j.jcis.2012.06.090

Hot melt poly-epsilon-caprolactone/poloxamine implantable matrices for sustained delivery of ciprofloxacin

Authors Puga, AM, Rey-Rico, A, Magarinos, B, Alvarez-Lorenzo, C, Concheiro, A
Journal ACTA BIOMATERIALIA Vol. 8 Num. 4 (pages 1507 to 1518)
DOI https://doi.org/10.1016/j.actbio.2011.12.020

Wound dressings loaded with an anti-inflammatory jucá (Libidibia ferrea) extract using supercritical carbon dioxide technology

Authors A.M.A.Diasa, Rey-Rico, A, R.A.Oliveiraa, S. Marceneiro, S. Marceneiro, C. Alvarez-Lorenzo, A. Concheiro, R.N.C. Júnior, M.E.M. Braga, H.C. de Sousa
Journal JOURNAL OF SUPERCRITICAL FLUIDS Vol. 74 (pages 34 to 45)
DOI https://doi.org/10.1016/j.supflu.2012.12.007

OSTEOGENIC EFFICIENCY OF IN SITU GELLING POLOXAMINE SYSTEMS WITH AND WITHOUT BONE MORPHOGENETIC PROTEIN-2

Authors Rey-Rico, A, Silva, M, Couceiro, J, Concheiro, A, Alvarez-Lorenzo, C
Journal EUROPEAN CELL & MATERIALS Vol. 21 (pages 317 to 340)
DOI https://doi.org/10.22203/ecm.v021a24

Bio-inspired porous SiC ceramics loaded with vancomycin for preventing MRSA infections

Authors Diaz-Rodriguez, P, Landin, M, Rey-Rico, A, Couceiro, J, Coenye, T, Gonzalez, P, Serra, J, Lopez-Alvarez, M, Leon, B
Journal JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE Vol. 22 Num. 2 (pages 339 to 347)
DOI https://doi.org/10.1007/s10856-010-4196-0

Inhibition of P-glycoprotein pumps by PEO-PPO amphiphiles: branched versus linear derivatives

Authors Alvarez-Lorenzo, C, Rey-Rico, A, Brea, J, Loza, MI, Concheiro, A, Sosnik, A
Journal NANOMEDICINE Vol. 5 Num. 9 (pages 1371 to 1383)
DOI https://doi.org/10.2217/nnm.10.53

N-alkylation of poloxamines modulates micellar assembly and encapsulation and release of the antiretroviral efavirenz

Authors Chiappetta, DA, Alvarez-Lorenzo, C, Rey-Rico, A, Taboada, P, Concheiro, A, Sosnik, A
Journal European Journal of Pharmaceutics and Biopharmaceutics Vol. 76 Num. 1 (pages 24 to 37)
DOI https://doi.org/10.1016/j.ejpb.2010.05.007

Poloxamine-based nanomaterials for drug delivery.

Authors Alvarez-Lorenzo C, Rey-Rico, A, Sosnik A, Taboada, P, Concheiro A
Journal FRONTIERS BIOSCIENCE Vol. 2 (pages 424 to 440)

Polysaccharides-based Hydrogels for the control delivery of therapeutic Biomacromolecules

Authors Rial-Hermida, Isabel. Rey-Rico, Ana. Carballo-Pedrares, Natalia. Mano Joao F
Book Soft Matter for Biomedical Applications
Publishing: Royal Society of Chemistry.
ISBN: 978-1-83916-112-4
Pages From 518 to 518541

Mesenchymal stem cells for cartilage repair in osteoarthritis

Authors Rey-Rico, A. Janina Frisch. Magali Cucchiarini
Book Frontiers in Stem Cell and Regenerative Medicine Research
Vol. 7 Publishing: Bentham Science Publishers (BSP) .
ISBN: 978-1-68108-553-1
Pages From 1 to 22

Controlled Gene Delivery Systems for Articular Cartilage Repair

Authors Magali Cucchiarini. Rey-Rico, A
Book Advances in Biomaterials for Biomedical Applications
Publishing: Spriger.
ISBN: 1869-8433
Pages From 261 to 300

Criogeles activados por genes para reparación de cartílago

Autor Natalia Carballo Pedrares
Director/s Silvia María Díaz Prado; Ana Rey Rico
Scope Facultad de Ciencias de la Salud
Qualification Sobresaliente Cum Laude

Development of new non-viral systems for genetic modification of senescent cells
Cellular Aging and Metabolism Symposium (CAMS) 2022
International

Authors Miranda- Balbuena, D, López-Seijas, J, Sacristan-Santos, M, Carballo-Pedrares, N, MC Arufe, Rey-Rico, A, Fafián-Labora J
Place Coruña, A (España)

In vitro screening of niosome formulations for the effective gene transfer of human mesenchymal stem cells
European Society of Gene and Cell Therapy (ESGCT) & British Society of Gene and Cell Therapy (BSGCT)
International

Authors Lopez-Seijas,J, Carballo-Pedrares, N, Miranda-Balbuena, D, Rey-Rico, A
Place Edimburgo (Reino Unido)

Effective chondrogenic differentiation of human mesenchymal stem cells via hyaluronic acid-based gene-activated cryogels
European Society of Gene and Cell Therapy (ESGCT) & British Society of Gene and Cell Therapy (BSGCT)
International

Authors Carballo-Pedrares, N, Lopez-Seijas, J, Miranda-Balbuena, D, Rey-Rico, A
Place Edimburgo (Reino Unido)

Development of new non-viral systems for genetic modification of senescent cells
European Society of Gene and Cell Therapy (ESGCT) & British Society of Gene and Cell Therapy (BSGCT)
International

Authors Miranda-Balbuena, D, Lopez-Seijas, J, Sacristan-Santos, M, Carballo-Pedrares, N, MC Arufe, Fafián-Labora J, Rey-Rico, A
Place Edimburgo (Reino Unido)

Gene delivery systems for cartilage repair
V scientific symposium Aging and aging-related diseases: from mechanism to advanced therapies
National

Authors Rey-Rico, A
Place Coruña, A (España)

Carbon dot-guided delivery of therapeutic (SOX9, TGF-ß) rAAV vectors to enhance the biological activity of human articular chondrocytes
American Society of Gene & Cell Therapy (ASGCT)
International

Authors Meng, W, Venkatesan, Jagadeesh K., Rey-Rico, A, Schmitt, Gertrud, Speicher-Mentges, Susanne, Pons, F, Madry, Henning, Lebeau, L, Cucchiarini, Magali
Place online (Estados Unidos)

Niosome-Based Gene Delivery Systems For Efficient Genetic Modification Of Human Bone Marrow Derived Mesenchymal Stem Cells
Virtual EFORT Congress - VEChybrid
International

Authors Iglesias-Fente, Alba, López-Seijas, J, Carballo-Pedrares, Natalia, José Señaris, Rey-Rico, Ana
Place Coruña, A (España)

Niosome-based nonviral gene delivery systems for the effective genetic modification of immortalized human mesenchymal stem cells
European Society for Biomaterials (ESB) 2021 (online congress)
International

Authors Carballo-Pedrares, N, Kattar, A, Concheiro, Angel, Alvarez-Lorenzo, C, Rey-Rico, A
Place Coruña, A (España)

Tween 60 cationic niosomes for drug and gene delivery
European Society for Biomaterials (ESB) 2021 (online congress)
International

Authors Kattar, A, Carballo-Pedrares, Natalia, Rey-Rico, A, Concheiro, A, Alvarez-Lorenzo, C
Place Coruña, A (España)

Efficient transfection of human bone marrow derived mesenchymal stem cells via niosomes carriers.
Tissue Engineering and Regenerative Medicine International Society (TERMIS) 6th World congress
International

Authors Carballo-Pedrares, Natalia, Rey-Rico, A
Place Maastricht (Países Bajos)

Design of non-viral gene activated cryogels for improving the transfection of human mesenchymal stem cells
International Cartilage Regeneration & Joint Preservation Society (ICRS) 2022
International

Authors Carballo-Pedrares, Natalia, Lopez-Seijas, J, Miranda-Balbuena, D, Rey-Rico, A
Place Berlin (Alemania)

Effects of raav-mediated overexpression of SOX9 and TGF-ß via carbon dots on the chondrogenesis of human bone marrow-derived mesenchymal stem cells
2020 World Congress on Osteoarthritis (OARSI)
International

Authors Rey-Rico, A, Venkatesan, Jagadesh Kumar, Schmitt, Gertrud, Pons, F, Lebeau, L, Cucchiarini, Magali
Place Viena (Austria)

Hyaluronic acid-based cryogel for regenerative medicine applications
Tissue Engineering and Regenerative Medicine International Society TERMIS ¿virtual seminar series
International

Authors Carballo-Pedrares, Natalia, Rey-Rico, Ana
Place Davis (Suiza)

Carbon dots nanocarriers for the effective rAAV mediated transduction of human osteoarthritic chondrocytes in vitro
2019 World Congress on Osteoarthritis (OARSI)
International

Authors Rey-Rico, A, Venkatesan, JK, Schmitt, G, Pons, F, Lebeau, L, Cucchiarini, M
Organization Osteoarthritis Research Society International (OARSI)
Place Toronto (Canadá)
DOI https://doi.org/10.1016/j.joca.2019.02.224

Chondrogenic differentiation processes in human bone marrow-derived mesenchymal stem cells upon rAAV mediated co-overexpression of TGF-beta and IGF-I
2019 World Congress on Osteoarthritis (OARSI)
International

Authors Morscheid, S, Rey-Rico, A, Schmitt, G, Madry, H, Cucchiarini, M, Venkatesan, JK
Organization Osteoarthritis Research Society International (OARSI)
Place Toronto (Canadá)
DOI https://doi.org/10.1016/j.joca.2019.02.221

Effective genetic modification of human bone marrow-derived mesenchymal stem cells upon control delivery of rAAV vectors via carbon dot nanocarriers
2019 World Congress on Osteoarthritis (OARSI)
International

Authors Rey-Rico, A, Venkatesan, JK, Schmitt, G, Pons, F, Lebeau, L, Cucchiarini, M
Organization Osteoarthritis Research Society International (OARSI)
Place Toronto (Canadá)
DOI https://doi.org/10.1016/j.joca.2019.02.223

rAAV mediated combined gene transfer and overexpression of TGF-beta and IGF-I in human bone marrow-derived mesenchymal stem cells upon implantation in a human osteochondral defect model.
2019 World Congress on Osteoarthritis (OARSI)
International

Authors Morscheid, S, Venkatesan, JK, Rey-Rico, A, Schmitt, G, Madry, H, Cucchiarini, M
Organization Osteoarthritis Research Society International (OARSI)
Place Toronto (Canadá)

Biological Effects of FGF-2 and IGF-I Co-Overexpression in Human Bone Marrow-Derived Mesenchymal Stem Cells via rAAV Vector Administration
21st Annual Meeting of the American-Society-of-Gene-and-Cell-Therapy (ASGCT)
International

Authors Venkatesan, JK, Bohm, T, Rey-Rico, A, Schmitt, G, Madry, H, Cucchiarini, M
Place Chicago (Estados Unidos)

Genetic Modification of Human Bone Marrow Aspirates via Delivery of Raav Vectors Coated on Pnass-Grafted Poly(epsilon-Caprolactone) Scaffolds.
21st Annual Meeting of the American-Society-of-Gene-and-Cell-Therapy (ASGCT)
International

Authors Venkatesan, JK, Leroux, A, Baumann, JS, Rey-Rico, A, Falentin-Daudre, C, Frisch, J, Madry, H, Migonney, V, Cucchiarini, M
Place Chicago (Estados Unidos)

rAAV SOX9 Gene Transfer Stimulates the Chondrogenic Differentiation Activities in Human Peripheral Blood Aspirates.
21st Annual Meeting of the American-Society-of-Gene-and-Cell-Therapy (ASGCT)
International

Authors Venkatesan, JK, Orth, P, Rey-Rico, A, Schmitt, G, Madry, H, Cucchiarini, M
Place Chicago (Estados Unidos)

Dual FGF-2 and SOX9 gene transfer via rAAV vectors: effects on the chondrogenic and metabolic processes in human bone marrow aspirates.
2018 Osteoarthritis Research Society International (OARSI) World Congress
International

Authors Tao, K, Rey-Rico, A, Venkatesan, JK, Schmitt, G, Madry, H, Cucchiarini, M
Place Liverpool (Reino Unido)

Controlled delivery of rAAV vectors via supramolecular polypseudorotaxane gels for cartilage tissue engineering approaches
2018 Annual Meeting of the Orthopaedic Research Society (ORS).
International

Authors Rey-Rico, A, Venkatesan, JK, Schmitt, Gertrud, Concheiro, A, Madry, H, Alvarez-Lorenzo, C, Cucchiarini, M
Organization Orthopaedic Research Society (ORS)
Place Nueva Orleans (Estados Unidos)

Influence of FGF-2 and SOX9 Overexpression via Recombinant Adeno-Associated Vector Gene Transfer on Human Bone Marrow-Derived Mesenchymal Stem Cells.
2018 Annual Meeting of the Orthopaedic Research Society (ORS).
International

Authors Lerner, L, Venkatesan, JK, Rey-Rico, A, Schmitt, G, Madry, H, Cucchiarini, M
Organization Orthopaedic Research Society (ORS)
Place Nueva Orleans (Estados Unidos)

PEO-PPO-PEO polymeric micelles as protective systems against inhibitors of rAAV-mediated gene transfer
2018 Annual Meeting of the Orthopaedic Research Society (ORS).
International

Authors Rey-Rico, A, Venkatesan, JK, Schmitt, G, Concheiro, A, Madry, H, Alvarez-Lorenzo, C, Cucchiarini, M
Organization Orthopaedic Research Society (ORS)
Place Nueva Orleans (Estados Unidos)

PEO-PPO-PEO micelles as effective rAAV-mediated delivery systems to overexpress SOX9 in human osteoarthritic articular chondrocytes
2018 Osteoarthritis Research Society International (OARSI) World Congress
International

Authors Rey-Rico, A, Venkatesan, JK, Schmitt, G, Madry, H, Cucchiarini, M
Place Liverpool (Reino Unido)

Terapia xénica para a reparación de cartilaxe
XI JORNADA CIÉNTÍFICA EN TERAPIA CELLULAR Y MEDICINA REGENERATIVA
International

Authors Rey-Rico, A
Place Coruña, A (España)

Terapia génica para la regeneración de cartílago
Programa de seminarios cientificos del Instituto de Investigación Biomedica de A Coruña (INIBIC)
Local

Authors Rey-Rico, A
Place Coruña, A (España)

Effective transduction of human articular chondrocytes in vitro and in a human osteochondral defect model via polymeric micelles.
2017 Deutscher Kongress für Orthopädie und Unfallchirurgie (DKOU)
National

Authors Rey-Rico, A, Frisch, J, Venkatesan, JK, Schmitt, G, Rial-Hermida, I, Taboada, P, Concheiro, A, Madry, H, Alvarez-Lorenzo, C, Cucchiarini, M
Place Berlin (Alemania)

Inhibition of rAAV-mediated transduction of human mesenchymal stem cells in the presence of platelet rich plasma.
2017 Deutscher Kongress für Orthopädie und Unfallchirurgie (DKOU)
National

Authors Rey-Rico, A, Venkatesan, JK, Müller, I, Frisch, J, Wildemann, B, Eichler, H, Madry, H, Cucchiarini, M
Place Berlin (Alemania)

Polypseudorotaxane gels as viral vectors release platforms for applications in cartilage regeneration
5th European Conference on Cyclodextrins
International

Authors Rey-Rico, A, Babicz, H, Madry, H, Concheiro, A, Cucchiarini, M, Alvarez-Lorenzo, C
Organization Universidade de Lisboa
Place Lisboa (Portugal)

rAAV-mediated modification of human articular chondrocytes via delivery in polymeric PEO-PPO-PEO micelles to overexpress TGF-ß.
Tissue Engineering and Regenerative Medicine International Society TERMIS ¿ EU conference
International

Authors Rey-Rico, A, Frisch, J, Venkatesan, JK, Concheiro, A, Alvarez-Lorenzo, C, Madry, H, Cucchiarini, M
Place Davos (Suiza)

PEO-PPO-PEO micelles as effective rAAV-mediated delivery systems to overexpress TGF-ß in human osteoarthritic articular chondrocytes
20th Annual Meeting of the American Society of Gene & Cell Therapy (ASGCT)
International

Authors Rey-Rico, A, Frisch, J, Venkatesan, JK, Concheiro, A, Alvarez-Lorenzo, C, Madry, H, Cucchiarini, M
Place Washington (Estados Unidos)

Durable rAAV-mediated gene transfer in human normal and osteoarthritic articular chondrocytes in three-dimensional culture conditions
2017 Annual Meeting of the Orthopaedic Research Society (ORS).
International

Authors Mueller, O, Frisch, J, Rey-Rico, A, Venkatesan, JK, Schmitt, G, Madry, H, Cucchiarini, M
Organization Orthopaedic Research Society (ORS).
Place San Diego (Estados Unidos)

Engineered cartilage tissue analogs based on human chondrocytes and the effects of gene-transfer via rAAV.
2017 Annual Meeting of the Orthopaedic Research Society (ORS).
International

Authors Mueller, O, Frisch, J, Rey-Rico, A, Venkatesan, JK, Schmitt, G, Madry, H, Cucchiarini M.
Organization Orthopaedic Research Society (ORS).
Place San Diego (Estados Unidos)

Genetic Modification of human bone marrow aspirates via delivery of rAAV vectors coated on PNaSS-grafted poly(epsilon-caprolactone) scaffolds
2017 Annual Meeting of the Orthopaedic Research Society (ORS).
International

Authors Venkatesan, JK, Leroux, A, Baumann, A, Rey-Rico, A, Falentin-Daudré, J, Frisch, J, Madry, H, Migonney, V, Cucchiarini, M
Organization Orthopaedic Research Society (ORS).
Place San Diego (Estados Unidos)

Interference of platelet rich plasma with gene transfer via rAAV vectors in human bone marrow-derived mesenchymal stem cells
2017 Annual Meeting of the Orthopaedic Research Society (ORS).
International

Authors Venkatesan, JK, Rey-Rico, A, Müller, I, Frisch, J, Wildemann, B, Eichler, H, Madry, H, Cucchiarini, M
Organization Orthopaedic Research Society (ORS).
Place San Diego (Estados Unidos)

Overexpression of human DKK1 via rAAV stimulates the chondrogenic differentiation processes in human bone marrow-derived mesenchymal stem cells
2017 Annual Meeting of the Orthopaedic Research Society (ORS).
International

Authors Venkatesan, JK, Rey-Rico, A, Frisch, J, Madry, H, Cucchiarini, M
Organization Orthopaedic Research Society (ORS).
Place San Diego (Estados Unidos)

PEO-PPO-PEO Micelles As rAAV Carriers For Effective Transduction Of Human Articular Chondrocytes In Vitro And In A Human Osteochondral Defect Model
2017 Annual Meeting of the Orthopaedic Research Society (ORS).
International

Authors Rey-Rico, A, Frisch, J, Venkatesan, JK, Schmitt, G, Rial-Hermida, I, Taboada, P, Concheiro, A, Madry, H, Alvarez-Lorenzo, C, Cucchiarini, M
Organization Orthopaedic Research Society (ORS).
Place San Diego (Estados Unidos)

Recombinant adeno-associated virus mediated cooverexpression of transforming growth factor beta and SOX9 genes enhace the metabolic and chondrogenic activities in human bone marrow aspirates.
2017 World Congress on Osteoarthritis (OARSI)
International

Authors Ke, T, Rey-Rico, A, Frisch, J, Venkatesan, JK, Schmitt, G, Madry, H, Lin, J, Cucchiarini, M
Organization 2018 World Congress on Osteoarthritis (OARSI)
Place Las Vegas (Estados Unidos)
DOI https://doi.org/10.1016/j.joca.2017.02.733

Evaluation of chondrogenesis in human bone marrow aspirates upon rAAV-mediated FGF-2 gene transfer and overexpression
2016 Deutscher Kongress für Orthopädie und Unfallchirurgie (DKOU)
National

Authors Frisch, J, Rey-Rico, A, Venkatesan, JK, Schmitt, G, Madry, H, Cucchiarini, M
Place Berlin (Alemania)

Overexpression of TGF-ß via rAAV gene transfer stimulates the chondrogenic processes in human bone marrow aspirates.
2016 Deutscher Kongress für Orthopädie und Unfallchirurgie (DKOU)
National

Authors Frisch, J, Rey-Rico, A, Venkatesan, JK, Schmitt, G, Madry, H, Cucchiarini, M
Place Berlin (Alemania)

PEO-PPO-PEO micelles as effective rAAV-mediated delivery systems to target human mesenchymal stem cells without altering their differentiation potency.
2016 Deutscher Kongress für Orthopädie und Unfallchirurgie (DKOU)
National

Authors Rey-Rico, A, Venkatesan, JK, Frisch, J, Rial-Hermida, I, Concheiro, A, Madry, H, Alvarez-Lorenzo, C, Cucchiarini, M
Place Berlin (Alemania)

Remodeling human osteoarthritic articular cartilage rAAV-mediated via combined gene transfer and overexpression of TGF-beta and sox9
2016 Deutscher Kongress für Orthopädie und Unfallchirurgie (DKOU)
National

Authors Ke, T, Frisch, J, Rey-Rico, A, Venkatesan, JK, Schmitt, G, Madry, H, Lin, JH, Cucchiarini, M
Place Berlin (Alemania)

rAAV-mediated sox9 overexpression induces chondrogenesis in human bone marrow aspirates seeded in woven poly(¿-caprolactone) scaffolds
2016 Deutscher Kongress für Orthopädie und Unfallchirurgie (DKOU)
National

Authors Venkatesan, JK, Moutos, F, Rey-Rico, A, Frisch, J, Schmitt, G, Guilak, F, Madry, H, Cucchiarini, M
Place Berlin (Alemania)

PEO-PPO-PEO micelles as new, effective rAAV-mediated gene delivery systems to modify human mesenchymal stem cells without altering their differentiation potency.
Les Journées Françaises de Biologie des Tissus Minéralisés (JFBTM)
National

Authors Rey-Rico, Ana, Frisch, J, Venkatesan, JK, Rial-Hermida, I, Concheiro, A, Madry, H, Cucchiarini, M
Organization Universidad de Lorraine
Place Nancy (Francia)

Comparative evaluation of the genetic modification of human and murine musculoskeletal cells via rAAV vectors in vitro and ex situ.
2016 Annual Meeting of the Orthopaedic Research Society (ORS).
International

Authors Daamouch, S, Rey-Rico, A, Frisch, J, Venkatesan, JK, Laschke, MW, Madry, H, Reboul, P, Cucchiarini, M
Organization Orthopaedic Research Society (ORS)
Place Orlando (Estados Unidos)

Effective rAAV-mediated Transduction Of Human Articular Chondrocytes Via Polymeric PEO-PPO-PEO Micelles In Vitro And In An Experimental Model Of Osteochondral Defect In Situ
2016 Annual Meeting of the Orthopaedic Research Society (ORS).
International

Authors Rey-Rico, A, Frisch, J, Venkatesan, JK, Concheiro, A, Madry, H, Alvarez-Lorenzo, C, Cucchiarini, M
Organization Orthopaedic Research Society (ORS)
Place Orlando (Estados Unidos)

Enhanced Proteoglycan Production of Primary Human Meniscal Fibrochondrocytes Cultivated in Biomedical-Grade, High Mannuronic Acid Content (BioMVM) Alginate 3-D Hydrogel Culture
2016 Annual Meeting of the Orthopaedic Research Society (ORS).
International

Authors Rey-Rico, A, Klich, A, Cucchiarini, M, Madry, H
Organization Orthopaedic Research Society (ORS)
Place Orlando (Estados Unidos)

Evaluation Of Chondrogenesis In Human Bone Marrow Aspirates Upon rAAV mediated FGF-2 Gene Transfer And Overexpression
2016 Annual Meeting of the Orthopaedic Research Society (ORS).
International

Authors Frisch, J, Rey-Rico, A, Venkatesan, JK, Schmitt, G, Madry, H, Cucchiarini, M
Organization Orthopaedic Research Society (ORS)
Place Orlando (Estados Unidos)

Manipulation Of Peripheral Blood Aspirates Via rAAV To Improve Cartilage Repair
2016 Annual Meeting of the Orthopaedic Research Society (ORS).
International

Authors Frisch, J, Venkatesan, JK, Rey-Rico, A, Orth, P, Schmitt, G, Madry, H, Cucchiarini, M
Organization Orthopaedic Research Society (ORS)
Place Orlando (Estados Unidos)

Overexpression Of TGFß Via rAAV Gene Transfer Stimulates The Chondrogenic Processes In Human Bone Marrow Aspirates
2016 Annual Meeting of the Orthopaedic Research Society (ORS).
International

Authors Frisch, J, Rey-Rico, A, Venkatesan, JK, Schmitt, G, Madry, H, Cucchiarini, M
Organization Orthopaedic Research Society (ORS)
Place Orlando (Estados Unidos)

PEO-PPO-PEO Micelles As Effective rAAV-mediated Delivery Systems To Genetically Modify Human Mesenchymal Stem Cells Without Altering Their Differentiation Potency
2016 Annual Meeting of the Orthopaedic Research Society (ORS).
International

Authors Rey-Rico, A, Venkatesan, JK, Frisch, J, Rial-Hermida, I, Concheiro, A, Madry, H, Alvarez-Lorenzo, C, Cucchiarini, M
Organization Orthopaedic Research Society (ORS)
Place Orlando (Estados Unidos)

rAAV-mediated SOX9 Overexpression Induces Chondrogenesis In Human Bone Marrow Aspirates Seeded In Woven Poly(¿-caprolactone) Scaffolds
2016 Annual Meeting of the Orthopaedic Research Society (ORS).
International

Authors Venkatesan, JK, Moutos, F, Rey-Rico, A, Frisch, J, Schmitt, G, Guilak, F, Madry, H, Cucchiarini, M
Organization Orthopaedic Research Society (ORS)
Place Orlando (Estados Unidos)

Controlled release of adeno-associated viral vectors (rAAV) from self-assembling peptide hydrogels to genetically modify human mesenchymal stem cells
IX Internacional Forum on Advances in Pharmaceutical Technology (CISDEM)
National

Authors Rey-Rico, A, Venkatesan, JK, Frisch, J, Schmitt, G, Mata, A, Semino, C, Madry, H, Cucchiarini, M
Organization Facultade de Farmacia
Place Santiago de Compostela (España)

Chondrogene Differenzierung genetisch modifizierter hMSCs mittels kontrollierter Freisetzung von rAAV-Vektoren aus selbstorganisierenden Peptid-Hydrogelen
2015 Deutscher Kongress für Orthopädie und Unfallchirurgie (DKOU)
National

Authors Rey-Rico, A, Venkatesan, JK, Frisch, J, Monge Marcet, A, Mata, A, Semino, C, Madry, H, Cucchiarini, M
Place Berlín (Alemania)

Effekte statischer und dynamischer Kulturbedingungen auf daschondrogene Differenzierungspotential humaner Knochenmarkaspiratenach rAAV-vermittelter Überexpression von sox9.
2015 Deutscher Kongress für Orthopädie und Unfallchirurgie (DKOU)
National

Authors Venkatesan, JK, Rey-Rico, A, Frisch, J, Schmitt, G, Madry, H, Cucchiarini, M
Place Berlín (Alemania)

Kontrollierte Freisetzung von rekombinanten adeno-assoziierten viralen (rAAV) Vektoren aus Alginat-Poloxamer Komplexsystemen
2015 Deutscher Kongress für Orthopädie und Unfallchirurgie (DKOU)
National

Authors Rey-Rico, A, Diaz-Rodriguez, P, Madry, H, Landin, M, Cucchiarini, M
Place Berlín (Alemania)

Verbesserte chondrogene Differenzierung in Knochenmarkaspiraten von Minischweinen nach rAAV-vermitteltem Gentransfer mit anschließender Überexpression des Transkriptionsfaktors sox9
2015 Deutscher Kongress für Orthopädie und Unfallchirurgie (DKOU)
National

Authors Frisch, J, Rey-Rico, A, Venkatesan, JK, Schmitt, G, Madry, H, Cucchiarini, M
Place Berlín (Alemania)

Vorteile der Nutzung von PEO-PPO Copolymeren für effektiven Gentransfer in humane, aus Knochnemark isolierte mesenchymale Stammzellen mittels rAAV-Vektoren
2015 Deutscher Kongress für Orthopädie und Unfallchirurgie (DKOU)
National

Authors Rey-Rico, A, Alvarez-Lorenzo, C, Concheiro, A, Madry, H, Cucchiarini, M
Place Berlín (Alemania)

rAAV-basierte genetische Modifikation von humanen Knochenmarkaspiraten, eingebettet in gewebte 3D Poly(Epsilon-Caprolacton) Scaffolds
2015 Deutscher Kongress für Orthopädie und Unfallchirurgie (DKOU)
National

Authors Cucchiarini, M, Frisch, J, Rey-Rico, A, Venkatesan, JK, Schmitt, G, Madry, H, Cucchiarini, M
Place Berlín (Alemania)

rAAV-vermittelte Überexpression von IGF-I und ihr Einfluss auf die chondrogene Differenzierung von humanen Knochenmarkaspiraten.
2015 Deutscher Kongress für Orthopädie und Unfallchirurgie (DKOU)
National

Authors Frisch, J, Rey-Rico, A, Venkatesan, JK, Schmitt, G, Madry, H, Cucchiarini, M
Place Berlín (Alemania)

Enhanced chondrogenic differentiation of human osteoarthritic bone marrow aspirates modified to overexpress the transcription factor SOX9 via rAAV-mediated gene transfer in dynamic versus static culture conditions
2015 Osteoarthritis Research Society International (OARSI) World Congress
International

Authors Venkatesan, JK, Rey-Rico, A, Frisch, J, Madry, H, Cucchiarini, M
Place Seattle (Estados Unidos)
DOI https://doi.org/10.1016/j.joca.2015.02.672

Benefits of biomedical versus nonbiomedical grade alginates for the durable and safe modification of hMSC via rAAV-mediated gene transfer.
2015 Annual Meeting of the Orthopaedic Research Society (ORS).
International

Authors Hunneshagen, C, Rey-Rico, A, Madry, H, Cucchiarini, M
Organization Orthopaedic Research Society (ORS)
Place Las Vegas (Estados Unidos)

Controlled release of rAAV vectors from alginate-poloxamer complex systems
2015 Annual Meeting of the Orthopaedic Research Society (ORS).
International

Authors Diaz-Rodriguez, P, Rey-Rico, A, Madry, H, Landin, M, Cucchiarini, M
Organization Orthopaedic Research Society (ORS)
Place Las Vegas (Estados Unidos)

Benefits of using PEO-PPO copolymers for the effective delivery of rAAV vectors in human bone marrow-derived mesenchymal stem cells
2015 Annual Meeting of the Orthopaedic Research Society (ORS).
International

Authors Rey-Rico, A, Alvarez-Lorenzo, C, Concheiro, A, Madry, H, Cucchiarini, M
Organization Orthopaedic Research Society (ORS)
Place Las Vegas (Estados Unidos)

Chondrogenic differentiation of genetically modified hMSC via controlled release of rAAV vectors from self-assembling peptide hydrogels
2015 Annual Meeting of the Orthopaedic Research Society (ORS).
International

Authors Rey-Rico, A, Venkatesan, JK, Frisch, J, Schmitt, G, Monge Marcet, A, Mata, A, Semino, C, Madry, H, Cucchiarini, M
Organization Orthopaedic Research Society (ORS)
Place Las Vegas (Estados Unidos)

Effects of rAAV Sox9 gene transfer upon the chondrogenic differentiation of hMSCs seeded in polyurethane scaffolds
2015 Annual Meeting of the Orthopaedic Research Society (ORS).
International

Authors Venkatesan, JK, Rey-Rico, A, Gardner, O, Schmitt, G, Alini, M, Stoddart, M, Cucchiarini, M, Madry, H
Organization Orthopaedic Research Society (ORS)
Place Las Vegas (Estados Unidos)

Effects of static versus dynamic culture conditions upon the chondrogenic differentiation potential of human bone marrow aspirates following rAAV-mediated overexpression of Sox9
2015 Annual Meeting of the Orthopaedic Research Society (ORS).
International

Authors Venkatesan, JK, Rey-Rico, A, Frisch, J, Schmitt, G, Madry, H, Cucchiarini, M
Organization Orthopaedic Research Society (ORS)
Place Las Vegas (Estados Unidos)

Enhanced chondrogenic differentiation processes in bone marrow aspirates from minipigs following rAAV-mediated gene transfer and overexpression of the transcription factor Sox9
2015 Annual Meeting of the Orthopaedic Research Society (ORS).
International

Authors Frisch, J, Rey-Rico, A, Venkatesan, JK, Schmitt, G, Cucchiarini, M, Madry, H
Organization Orthopaedic Research Society (ORS)
Place Las Vegas (Estados Unidos)

Improved conditions to enhance the chondrogenic differentiation processes in human primary bone marrow aspirates via rAAV-mediated gene transfer.
2015 Annual Meeting of the Orthopaedic Research Society (ORS).
International

Authors Rey-Rico, A, Frisch, J, Venkatesan, JK, Schmitt, G, Madry, H, Cucchiarini, M
Organization Orthopaedic Research Society (ORS)
Place Las Vegas (Estados Unidos)

Influence of IGF-I overexpression via rAAV gene transfer upon the chondrogenic differentiation potential of human bone marrow aspirates
2015 Annual Meeting of the Orthopaedic Research Society (ORS).
International

Authors Frisch, J, Rey-Rico, A, Venkatesan, JK, Schmitt, G, Cucchiarini, M, Madry, H
Organization Orthopaedic Research Society (ORS)
Place Las Vegas (Estados Unidos)

rAAV-based genetic modification of human bone marrow aspirates seeded in 3D woven poly(epsilon-caprolactone) (PCL) scaffolds.
2015 Annual Meeting of the Orthopaedic Research Society (ORS).
International

Authors Frisch, J, Rey-Rico, A, Venkatesan, JK, Moutos, F, Schmitt, G, Guilak, F, Madry, H, Cucchiarini, M
Organization Orthopaedic Research Society (ORS)
Place Las Vegas (Estados Unidos)

Enhanced Chondrogenic Potential of Human Bone Marrow Aspirates Upon rAAV-Mediated Overexpression of IGF-I
18th Annual Meeting of the American Society (ASGCT)
International

Authors Frisch, J, Rey-Rico, A, Venkatesan, JK, Madry, H, Cucchiarini, M
Place Nueva Orleans (Estados Unidos)
DOI https://doi.org/10.1016/s1525-0016(16)34014-x

Effects of IGF-I overexpression on the chondrogenic potential of human bone marrow aspirates modified via rAAV gene transfer
2015 World Congress on Osteoarthritis (OARSI)
International

Authors Frisch, J, Rey-Rico, A, Venkatesan, JK, Madry, H, Cucchiarini, M
Organization Osteoarthitis Research Society International (OARSI)
Place Seattle (Estados Unidos)
DOI https://doi.org/10.1016/j.joca.2015.02.673

Effects of exosomes compared with autologous conditioned serum upon the metabolic activities of human osteoarthritic articular cartilage in situ
2015 World Congress on Osteoarthritis (OARSI)
International

Authors Rey-Rico, A, Reinecke, J, Wehling, P, Cucchiarini, M, Madry, H
Organization Osteoarthitis Research Society International (OARSI)
Place Seattle (Estados Unidos)
DOI https://doi.org/10.1016/j.joca.2015.02.736

TGF-beta1-freisetzende Poly(Ether-Ester)-Multiblock-Scaffolds ermöglichen eine effiziente chondrogene Differenzierung von humanen mesenchymalen Stammzellen.
2014 Deutscher Kongress für Orthopädie und Unfallchirurgie (DKOU)
National

Authors Rey-Rico, A, Venkatesan, JK, Sohier, J, Schmitt, G, Moroni, L, Cucchiarini, M, Madry, H
Place Berlín (Alemania)

TGF-beta1-releasing poly(ether-ester) multiblock scaffolds lead to efficient chondrogenic differentiation of human mesenchymal stem cells.
2014 Annual Meeting of the Orthopaedic Research Society (ORS)
International

Authors Rey-Rico, A, Venkatesan, JK, Sohier, J, Moroni, L, Cucchiarini, M, Madry, H
Organization Orthopaedic Research Society (ORS)
Place Nueva Orleans (Estados Unidos)

Efficacy and stability of gene transfer via rAAV in human bone marrow aspirates -a comparative analysis in dynamic versus static culture conditions
2014 Annual Meeting of the Orthopaedic Research Society (ORS)
International

Authors Venkatesan, JK, Rey-Rico, A, Schmitt, G, Madry, H, Cucchiarini, M
Organization Orthopaedic Research Society (ORS)
Place Nueva Orleans (Estados Unidos)

Evaluation of controlled release of rAAV vectors using self-assembling peptide hydrogels.
2014 Annual Meeting of the Orthopaedic Research Society (ORS)
International

Authors Rey-Rico, A, Venkatesan, JK, Schmitt, G, Monge-Marcet, A, Mata, A, Semino, C, Madry, H, Cucchiarini, M
Organization Orthopaedic Research Society (ORS)
Place Nueva Orleans (Estados Unidos)

Positions

Academic or management positions held by teacher.

Consello do Departamento Bioloxía

PDI (Membros Natos)

From 15/03/2023.

Comisión Académica M.U. en Biología Molecular, Celular y Genética (2021)

Vocal PDI

From 20/04/2022 to 29/05/2023.

Consello do Departamento Bioloxía

PDI (Membros Natos)