Dra. Ana Rey Rico  

Investigador contratado en el programa InTalent UDC-INDITEX (PR-PX-InTLT)

Investigación  Grupo de investigación Grupo de investigación en Terapia Celular y Medicina Regenerativa
Líneas de investigación No figuran en el gestor curricular de la UDC (SUXI).
Contacto Directorio de la UDC

Docencia

Docencia impartida

En este apartado se muestra la docencia impartida en grados, másteres y resto de estudios oficiales en los últimos 6 años.

Asignatura y estudios en la que se imparte Horas totales
Anatomía I e Histología 9
Anatomía y Cinesiología del Movimiento Humano 20
Aplicación de las Técnicas de Investigación en Ciencias de la Salud 6
Técnicas de Cultivo Celular 8,5
Técnicas de Manipulación y Análisis de Ácidos Nucleicos 20
Asignatura y estudios en la que se imparte Horas totales
Aplicación de las Técnicas de Investigación en Ciencias de la Salud
Máster Universitario en Asistencia e Investigación Sanitaria
6
Estancia en un Grupo de Investigación
Máster Universitario en Asistencia e Investigación Sanitaria
3
Seminarios Científicos
Máster Universitario en Asistencia e Investigación Sanitaria
6
Técnicas de Cultivo Celular
Máster Universitario en Asistencia e Investigación Sanitaria
8,5
Técnicas de Manipulación y Análisis de Ácidos Nucleicos
Máster Universitario en Asistencia e Investigación Sanitaria
20

Trabajos de fin de grado y máster

Dirigidos o codirigidos por el/la docente desde el año 2013.

Sistemas de administración de genes basados en péptidos de penetración celular para la transfección efectiva de células madre mesenquimales
Sistemas de administración de genes para la transfección efectiva de células madre mesenquimales

Resultados de investigación

Puede consultar los méritos de investigación seleccionando un tipo de mérito y el año.

Criogeles activados por genes para reparación de cartílago

Entidad financiadora Ministerio de Ciencia, Innovación y Universidades
Investigadores principales Ana Rey Rico
Tipo Proyecto Programas Nacionales
Fechas Desde 01/01/2019 a 31/12/2021

Mechanisms of self-assembly temperature-sensitive polymers for enhanced rAAV-mediated gene transfer into human mesenchymal stem cells

Entidad financiadora DFG ( Deutsche Forschungsgemeinschaft)
Investigadores principales Ana Rey Rico
Tipo Proyecto Programas Nacionales
Fechas Desde 01/01/2016 a 31/12/2017

Homburger Forschungsförderungsprogramm HOMFOR: Mejor proyecto de investigación Facultad de Medicina, Universidad de Saarland

Entidad financiadora Center of Experimental Orthopaedics, Saarland University Medical Center
Investigadores principales Ana Rey Rico, Magali Cucchiarini, Henning Madry
Tipo Proyecto Otros Programas
Fechas Desde 01/01/2015 a 31/12/2015

Current Trends in Viral Gene Therapy for Human Orthopaedic Regenerative Medicine

Autores Jagadeesh Kumar Venkatesan, Rey-Rico, A, Magali Cucchiarini
Revista Tissue Engineering and Regenerative Medicine (págs. 1 a 11)
DOI https://doi.org/10.1007/s13770-019-00179-x

Remodeling of Human Osteochondral Defects via rAAV-Mediated Co-Overexpression of TGF-beta and IGF-I from Implanted Human Bone Marrow-Derived Mesenchymal Stromal Cells.

Autores Morscheid, Stephanie, Venkatesan, Jagadeesh Kumar, Rey-Rico, Ana, Schmitt, Gertrud, Cucchiarini, Magali
Revista Journal of Clinical Medicine Vol. 8 Núm. 9
DOI https://doi.org/10.3390/jcm8091326

Therapeutic Effects of rAAV-Mediated Concomittant Gene Transfer and Overexpression of TGF- and IGF-I on the Chondrogenesis of Human Bone-Marrow-Derived Mesenchymal Stem Cells

Autores Morscheid, S, Rey-Rico, A, Schmitt, G, Madry, H, Cucchiarini, M, Venkatesan, JK
Revista International Journal of Molecular Sciences Vol. 20 Núm. 10
DOI https://doi.org/10.3390/ijms20102591

Supramolecular Cyclodextrin-Based Hydrogels for Controlled Gene Delivery

Autores Rey-Rico, A, Cucchiarini, M
Revista Polymers Vol. 11 Núm. 3
DOI https://doi.org/10.3390/polym11030514

PEO-PPO-PEO Tri-Block Copolymers for Gene Delivery Applications in Human Regenerative Medicine-An Overview

Autores Rey-Rico, A, Cucchiarini, M
Revista International Journal of Molecular Sciences Vol. 19 Núm. 3
DOI https://doi.org/10.3390/ijms19030775

Effective Remodelling of Human Osteoarthritic Cartilage by sox9 Gene Transfer and Overexpression upon Delivery of rAAV Vectors in Polymeric Micelles

Autores Rey-Rico, A, Venkatesan, JK, Schmitt, G, Speicher-Mentges, S, Madry, H, Cucchiarini, M
Revista MOLECULAR PHARMACEUTICS Vol. 15 Núm. 7 (págs. 2816 a 2826)
DOI https://doi.org/10.1021/acs.molpharmaceut.8b00331

Chondrogenic Differentiation Processes in Human Bone-Marrow Aspirates Seeded in Three-Dimensional-Woven Poly(¿-Caprolactone) Scaffolds Enhanced by Recombinant Adeno-Associated Virus-Mediated SOX9 Gene Transfer

Autores Jagadeesh Kumar Venkatesan, FT Moutos, Rey-Rico, A, BT Estes, Janina Fisch, Gertrud Schmitt, Henning Madry, Guilak, F, Magali Cucchiarini
Revista HUMAN GENE THERAPY Vol. 29 Núm. 11 (págs. 1277 a 1286)
DOI https://doi.org/10.1089/hum.2017.165

Improved Chondrogenic Differentiation of rAAV SOX9-Modified Human MSCs Seeded in Fibrin-Polyurethane Scaffolds in a Hydrodynamic Environment

Autores Jagadeesh Kumar Venkatesan, Gardner, O, Rey-Rico, A, David Eglin, Mauro Alini, Martin Stoddart, Magali Cucchiarini, Henning Madry
Revista International Journal of Molecular Sciences
DOI https://doi.org/10.3390/ijms19092635

Antimicrobial Properties and Osteogenicity of Vancomycin-Loaded Synthetic Scaffolds Obtained by Supercritical Foaming

Autores Carlos García Gonzalez, Joana Barros, Rey-Rico, A, Pablo Redondo, Jose Luis Gómez Amoza, Concheiro, A, Carmen Alvarez Lorenzo, Fernando J Monteiro
Revista ACS Applied Materials & Interfaces Vol. 10 (págs. 3349 a 3360)
DOI https://doi.org/10.1021/acsami.7b17375

Sustained spatiotemporal release of TGF-ß1 confers enhanced very early chondrogenic differentiation during osteochondral repair in specific topographic patterns

Autores Ann-Kathrin Asen, Lars Goebel, Rey-Rico, A, Jerome Sohier, Magali Cucchiarini, Henning Madry
Revista FASEB JOURNAL Vol. 32 (págs. 5298 a 5311)
DOI https://doi.org/10.1096/fj.201800105r

rAAV-mediated overexpression of TGF-beta via vector delivery in polymeric micelles stimulates the biological and reparative activities of human articular chondrocytes in vitro and in a human osteochondral defect model

Autores Rey-Rico, A, Venkatesan, JK, Schmitt, G, Concheiro, A, Madry, H, Alvarez-Lorenzo, C, Cucchiarini, M
Revista INTERNATIONAL JOURNAL OF NANOMEDICINE Vol. 12 (págs. 6985 a 6996)
DOI https://doi.org/10.2147/ijn.s144579

Supramolecular polypseudorotaxane gels for controlled delivery of rAAV vectors in human mesenchymal stem cells for regenerative medicine

Autores Rey-Rico, A, Babicz, H, Madry, H, Concheiro, A, Alvarez-Lorenzo, C, Cucchiarini, M
Revista INTERNATIONAL JOURNAL OF PHARMACEUTICS Vol. 531 Núm. 2 (págs. 492 a 503)
DOI https://doi.org/10.1016/j.ijpharm.2017.05.050

Peripheral blood aspirates overexpressing IGF-I via rAAV gene transfer undergo enhanced chondrogenic differentiation processes

Autores Frisch, J, Orth, P, Rey-Rico, A, Venkatesan, JK, Schmitt, G, Madry, H, Kohn, D, Cucchiarini, M
Revista JOURNAL OF CELLULAR AND MOLECULAR MEDICINE Vol. 21 Núm. 11 (págs. 2748 a 2758)
DOI https://doi.org/10.1111/jcmm.13190

Effects of combined rAAV-mediated TGF-beta and sox9 gene transfer and overexpression on the metabolic and chondrogenic activities in human bone marrow aspirates.

Autores Tao, Ke, Rey-Rico, A, Frisch, Janina, Venkatesan, Jagadeesh Kumar, Schmitt, Gertrud, Madry, Henning, Lin, Jianhao, Cucchiarini, Magali
Revista Journal of experimental orthopaedics Vol. 4 Núm. 1
DOI https://doi.org/10.1186/s40634-017-0077-5

Impact of mechanical stimulation on the chondrogenic processes in human bone marrow aspirates modified to overexpress sox9 via rAAV vectors.

Autores Venkatesan, Jagadeesh K, Frisch, Janina, Rey-Rico, A, Schmitt, Gertrud, Madry, Henning, Cucchiarini, Magali
Revista Journal of experimental orthopaedics Vol. 4 Núm. 1
DOI https://doi.org/10.1186/s40634-017-0097-1

Genetic Modification of Human Peripheral BloodAspirates Using Recombinant Adeno-Associated ViralVectors for Articular Cartilage Repair with a Focus onChondrogenic Transforming Growth Factor-bGene Delivery

Autores JANINA FRISCH, PATRIC KORTH, AGADEESH KUMAR VENKATESAN, Rey-Rico, A, GERTRUD SCHMITT, DIETER KOHN, HENNING MADRY,, MAGALI CUCCHIARINI
Revista STEM CELLS TRANSLATIONAL MEDICINE Vol. 6 Núm. 1 (págs. 249 a 260)
DOI https://doi.org/10.5966/sctm.2016-0149

Smart and Controllable rAAV Gene Delivery Carriers in Progenitor Cells for Human Musculoskeletal Regenerative Medicine with a Focus on the Articular Cartilage.

Autores Rey-Rico, A, Magali Cucchiarini
Revista Current Gene Therapy Vol. 17 Núm. 2
DOI https://doi.org/10.2174/1566523217666170510162459

Hydrogels for precision meniscus tissue engineering: a comprehensive review.

Autores Rey-Rico, A, Cucchiarini M, Madry H
Revista CONNECTIVE TISSUE RESEARCH Vol. 58 Núm. 3-4 (págs. 317 a 328)
DOI https://doi.org/10.1080/03008207.2016.1276576.

Effects of rAAV-mediated FGF-2 gene transfer and overexpression upon the chondrogenic differentiation processes in human bone marrow aspirates.

Autores Frisch, Janina, Venkatesan, Jagadeesh K, Rey-Rico, A, Zawada, Adam M, Schmitt, Gertrud, Madry, Henning, Cucchiarini, Magali
Revista Journal of experimental orthopaedics Vol. 3 Núm. 1
DOI https://doi.org/10.1186/s40634-016-0052-6

Biomedical-grade, high mannuronic acid content (BioMVM) alginate enhances the proteoglycan production of primary human meniscal fibrochondrocytes in a 3-D microenvironment

Autores Rey-Rico, A, Klich, A, Cucchiarini, M, Madry, H
Revista Scientific Reports Vol. 6
DOI https://doi.org/10.1038/srep28170

TGF- gene transfer and overexpression via rAAV vectors stimulates chondrogenic events in human bone marrow aspirates

Autores Frisch, J, Rey-Rico, A, Venkatesan, JK, Schmitt, G, Madry, H, Cucchiarini, M
Revista JOURNAL OF CELLULAR AND MOLECULAR MEDICINE Vol. 20 Núm. 3 (págs. 430 a 440)
DOI https://doi.org/10.1111/jcmm.12774

rAAV-mediated combined gene transfer and overexpression of TGF- and SOX9 remodels human osteoarthritic articular cartilage

Autores Tao, K, Rey-Rico, A, Frisch, J, Venkatesan, JK, Schmitt, G, Madry, H, Lin, JH, Cucchiarini, M
Revista JOURNAL OF ORTHOPAEDIC RESEARCH Vol. 34 Núm. 12 (págs. 2181 a 2190)
DOI https://doi.org/10.1002/jor.23228

rAAV-mediated overexpression of sox9, TGF-beta and IGF-I in minipig bone marrow aspirates to enhance the chondrogenic processes for cartilage repair

Autores Frisch, J, Rey-Rico, A, Venkatesan, JK, Schmitt, G, Madry, H, Cucchiarini, M
Revista GENE THERAPY Vol. 23 Núm. 3 (págs. 247 a 255)
DOI https://doi.org/10.1038/gt.2015.106

Co-overexpression of TGF-beta and SOX9 via rAAV gene transfer modulates the metabolic and chondrogenic activities of human bone marrow-derived mesenchymal stem cells

Autores Tao, K, Frisch, J, Rey-Rico, A, Venkatesan, JK, Schmitt, G, Madry, H, Lin, JH, Cucchiarini, M
Revista Stem Cell Research & Therapy Vol. 7
DOI https://doi.org/10.1186/s13287-016-0280-9

Hydrogel-Based Controlled Delivery Systems for Articular Cartilage Repair

Autores Rey-Rico, A, Henning Madry, Magali Cucchiarini
Revista BioMed Research International
DOI https://doi.org/10.1155/2016/1215263

Recent tissue engineering-based advances for effective rAAV-mediated gene transfer in the musculoskeletal system

Autores Magali Cucchiarini, Rey-Rico, A
Revista Bioengineered Vol. 7 Núm. 3
DOI https://doi.org/10.1080/21655979.2016.1187347

Effective genetic modification and differentiation of hMSCs upon controlled release of rAAV vectors using alginate/poloxamer composite systems

Autores Diaz-Rodriguez, P, Rey-Rico, A, Madry, H, Landin, M, Cucchiarini, M
Revista INTERNATIONAL JOURNAL OF PHARMACEUTICS Vol. 496 Núm. 2 (págs. 614 a 626)
DOI https://doi.org/10.1016/j.ijpharm.2015.11.008

PEO-PPO-PEO micelles as effective rAAV-mediated gene delivery systems to target human mesenchymal stem cells without altering their differentiation potency

Autores Rey-Rico, A, Venkatesan, JK, Frisch, J, Rial-Hermida, I, Schmitt, G, Concheiro, A, Madry, H, Alvarez-Lorenzo, C, Cucchiarini, M
Revista ACTA BIOMATERIALIA Vol. 27 (págs. 42 a 52)
DOI https://doi.org/10.1016/j.actbio.2015.08.046

Chondrogenic Differentiation Processes in Human Bone Marrow Aspirates upon rAAV-Mediated Gene Transfer and Overexpression of the Insulin-Like Growth Factor I

Autores Frisch, J, Rey-Rico, A, Venkatesan, JK, Schmitt, G, Madry, H, Cucchiarini, M
Revista TISSUE ENGINEERING PART C-METHODS Vol. 21 (págs. 2460 a 2471)
DOI https://doi.org/10.1089/ten.tea.2014.0679

Effective and durable genetic modification of human mesenchymal stem cells via controlled release of rAAV vectors from self-assembling peptide hydrogels with a maintained differentiation potency

Autores Rey-Rico, A, Venkatesan, JK, Frisch, J, Schmitt, G, Monge-Marcet, A, Lopez-Chicon, P, Mata, A, Semino, C, Madry, H, Cucchiarini, M
Revista ACTA BIOMATERIALIA Vol. 18 (págs. 118 a 127)
DOI https://doi.org/10.1016/j.actbio.2015.02.013

Adapted chondrogenic differentiation of human mesenchymal stem cells via controlled release of TGF-beta 1 from poly(ethylene oxide)-terephtalate/poly(butylene terepthalate) multiblock scaffolds

Autores Rey-Rico, A, Venkatesan, JK, Sohier, J, Moroni, L, Cucchiarini, M, Madry, H
Revista JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A Vol. 103 Núm. 1 (págs. 371 a 383)
DOI https://doi.org/10.1002/jbm.a.35181

Determination of effective rAAV-mediated gene transfer conditions to support chondrogenic differentiation processes in human primary bone marrow aspirates

Autores Rey-Rico, A, Frisch, J, Venkatesan, JK, Schmitt, G, Madry, H, Cucchiarini, M
Revista GENE THERAPY Vol. 22 Núm. 1 (págs. 50 a 57)
DOI https://doi.org/10.1038/gt.2014.90

Supramolecular cyclodextrin-based drug nanocarriers

Autores Simões SM, Rey-Rico, A, Concheiro A, Alvarez-Lorenzo C.
Revista CHEM. COMMUN. Vol. 51 Núm. 29 (págs. 6275 a 6289)
DOI https://doi.org/10.1039/c4cc10388b

Determination of the Chondrogenic Differentiation Processes in Human Bone Marrow-Derived Mesenchymal Stem Cells Genetically Modified to Overexpress Transforming Growth Factor-beta via Recombinant Adeno-Associated Viral Vectors

Autores Frisch, J, Venkatesan, JK, Rey-Rico, A, Schmitt, G, Madry, H, Cucchiarini, M
Revista HUMAN GENE THERAPY Vol. 25 Núm. 12 (págs. 1050 a 1060)
DOI https://doi.org/10.1089/hum.2014.091

Nonviral gene transfer into human meniscal cells. Part II: effect of three-dimensional environment and overexpression of human fibroblast growth factor 2

Autores Lee, HP, Rey-Rico, A, Cucchiarini, M, Madry, H
Revista INTERNATIONAL ORTHOPAEDICS Vol. 38 Núm. 9 (págs. 1931 a 1936)
DOI https://doi.org/10.1007/s00264-014-2405-z

Influence of insulin-like growth factor I overexpression via recombinant adeno-associated vector gene transfer upon the biological activities and differentiation potential of human bone marrow-derived mesenchymal stem cells

Autores Frisch, J, Venkatesan, JK, Rey-Rico, A, Schmitt, G, Madry, H, Cucchiarini, M
Revista Stem Cell Research & Therapy Vol. 5
DOI https://doi.org/10.1186/scrt491

Current progress in stem cell-based gene therapy for articular cartilage repair.

Autores Janina Frisch, Jagadeesh K Venkatesan, Rey-Rico, A, Henning Madry, Magali Cucchiarini
Revista Current Stem Cell Research & Therapy Vol. 10 Núm. 2
DOI https://doi.org/10.2174/1574888x09666140922112326

Transforming growth factor Beta-releasing scaffolds for cartilage tissue engineering.

Autores Madry H, Rey-Rico, A, Venkatesan, JK, Johnstone B, Cucchiarini M.
Revista Tissue Engineering Part B: Reviews Vol. 20 Núm. 2 (págs. 106 a 125)
DOI https://doi.org/10.1089/ten.teb.2013.0271

Current perspectives in stem cell research for knee cartilage repair.

Autores Patrick Orth, Rey-Rico, A, Jagadeesh K Venkatesan, Henning Madry, Magali Cucchiarini
Revista Stem Cells and Cloning Vol. 7 (págs. 1 a 17)
DOI https://doi.org/10.2147/sccaa.s42880

Poly(styrene oxide)-poly(ethylene oxide) block copolymers: From ¿classical¿ chemotherapeutic nanocarriers to active cell-response inducers

Autores A. Cambón, Rey-Rico, A, S. Barbosa, J.F.A. Soltero, S.G. Yeates, J. Brea, M.I. Loza, C. Alvarez-Lorenzo, A. Concheiro, Taboada, P, V. Mosquera
Revista JOURNAL OF CONTROLLED RELEASE Vol. 167 Núm. 1 (págs. 68 a 75)
DOI https://doi.org/10.1016/j.jconrel.2013.01.010

Doxorubicin-loaded micelles of reverse poly(butylene oxide)-poly(ethylene oxide)-poly(butylene oxide) block copolymers as efficient "active" chemotherapeutic agents

Autores Cambon, A, Rey-Rico, A, Mistry, D, Brea, J, Loza, MI, Attwood, D, Barbosa, S, Alvarez-Lorenzo, C, Concheiro, A, Taboada, P, Mosquera, V
Revista INTERNATIONAL JOURNAL OF PHARMACEUTICS Vol. 445 Núm. 1-2 (págs. 47 a 57)
DOI https://doi.org/10.1016/j.ijpharm.2013.01.056

rAAV-mediated overexpression of TGF-beta stably restructures human osteoarthritic articular cartilage in situ

Autores Venkatesan, JK, Rey-Rico, A, Schmitt, G, Wezel, A, Madry, H, Cucchiarini, M
Revista JOURNAL OF TRANSLATIONAL MEDICINE Vol. 11 (págs. 211 a 211)
DOI https://doi.org/10.1186/1479-5876-11-211

Poly(ethylene oxide)-poly(styrene oxide)-poly(ethylene oxide) copolymers: Micellization, drug solubilization, and gelling features

Autores Cambon, A, Barbosa, S, Rey-Rico, A, Figueroa-Ochoa, EB, Soltero, JFA, Yeates, SG, Alvarez-Lorenzo, C, Concheiro, A, Taboada, P, Mosquera, V
Revista JOURNAL OF COLLOID AND INTERFACE SCIENCE Vol. 387 (págs. 275 a 284)
DOI https://doi.org/10.1016/j.jcis.2012.06.090

Hot melt poly-epsilon-caprolactone/poloxamine implantable matrices for sustained delivery of ciprofloxacin

Autores Puga, AM, Rey-Rico, A, Magarinos, B, Alvarez-Lorenzo, C, Concheiro, A
Revista ACTA BIOMATERIALIA Vol. 8 Núm. 4 (págs. 1507 a 1518)
DOI https://doi.org/10.1016/j.actbio.2011.12.020

Wound dressings loaded with an anti-inflammatory jucá (Libidibia ferrea) extract using supercritical carbon dioxide technology

Autores A.M.A.Diasa, Rey-Rico, A, R.A.Oliveiraa, S. Marceneiro, S. Marceneiro, C. Alvarez-Lorenzo, A. Concheiro, R.N.C. Júnior, M.E.M. Braga, H.C. de Sousa
Revista JOURNAL OF SUPERCRITICAL FLUIDS Vol. 74 (págs. 34 a 45)
DOI https://doi.org/10.1016/j.supflu.2012.12.007

OSTEOGENIC EFFICIENCY OF IN SITU GELLING POLOXAMINE SYSTEMS WITH AND WITHOUT BONE MORPHOGENETIC PROTEIN-2

Autores Rey-Rico, A, Silva, M, Couceiro, J, Concheiro, A, Alvarez-Lorenzo, C
Revista EUROPEAN CELL & MATERIALS Vol. 21 (págs. 317 a 340)
DOI https://doi.org/10.22203/ecm.v021a24

Bio-inspired porous SiC ceramics loaded with vancomycin for preventing MRSA infections

Autores Diaz-Rodriguez, P, Landin, M, Rey-Rico, A, Couceiro, J, Coenye, T, Gonzalez, P, Serra, J, Lopez-Alvarez, M, Leon, B
Revista JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE Vol. 22 Núm. 2 (págs. 339 a 347)
DOI https://doi.org/10.1007/s10856-010-4196-0

Inhibition of P-glycoprotein pumps by PEO-PPO amphiphiles: branched versus linear derivatives

Autores Alvarez-Lorenzo, C, Rey-Rico, A, Brea, J, Loza, MI, Concheiro, A, Sosnik, A
Revista NANOMEDICINE Vol. 5 Núm. 9 (págs. 1371 a 1383)
DOI https://doi.org/10.2217/nnm.10.53

N-alkylation of poloxamines modulates micellar assembly and encapsulation and release of the antiretroviral efavirenz

Autores Chiappetta, DA, Alvarez-Lorenzo, C, Rey-Rico, A, Taboada, P, Concheiro, A, Sosnik, A
Revista EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS Vol. 76 Núm. 1 (págs. 24 a 37)
DOI https://doi.org/10.1016/j.ejpb.2010.05.007

Poloxamine-based nanomaterials for drug delivery.

Autores Alvarez-Lorenzo C, Rey-Rico, A, Sosnik A, Taboada, P, Concheiro A
Revista FRONTIERS BIOSCIENCE Vol. 2 (págs. 424 a 440)

Mesenchymal stem cells for cartilage repair in osteoarthritis

Autores Rey-Rico, A. Janina Frisch. Magali Cucchiarini
Libro Frontiers in Stem Cell and Regenerative Medicine Research
Vol. 7 Edita Bentham Science Publishers (BSP) .
ISBN: 978-1-68108-553-1
Páginas De la 1 a la 22

Controlled Gene Delivery Systems for Articular Cartilage Repair

Autores Magali Cucchiarini. Rey-Rico, A
Libro Advances in Biomaterials for Biomedical Applications
Edita Spriger.
ISBN: 1869-8433
Páginas De la 261 a la 300

Carbon dots nanocarriers for the effective rAAV mediated transduction of human osteoarthritic chondrocytes in vitro
2019 World Congress on Osteoarthritis (OARSI)
Internacional

Autores Rey-Rico, A, Venkatesan, JK, Schmitt, G, Pons, F, Lebeau, L, Cucchiarini, M
Organizador Osteoarthritis Research Society International (OARSI)
Lugar Toronto (Canadá)
DOI https://doi.org/10.1016/j.joca.2019.02.224

Chondrogenic differentiation processes in human bone marrow-derived mesenchymal stem cells upon rAAV mediated co-overexpression of TGF-beta and IGF-I
2019 World Congress on Osteoarthritis (OARSI)
Internacional

Autores Morscheid, S, Rey-Rico, A, Schmitt, G, Madry, H, Cucchiarini, M, Venkatesan, JK
Organizador Osteoarthritis Research Society International (OARSI)
Lugar Toronto (Canadá)
DOI https://doi.org/10.1016/j.joca.2019.02.221

Effective genetic modification of human bone marrow-derived mesenchymal stem cells upon control delivery of rAAV vectors via carbon dot nanocarriers
2019 World Congress on Osteoarthritis (OARSI)
Internacional

Autores Rey-Rico, A, Venkatesan, JK, Schmitt, G, Pons, F, Lebeau, L, Cucchiarini, M
Organizador Osteoarthritis Research Society International (OARSI)
Lugar Toronto (Canadá)
DOI https://doi.org/10.1016/j.joca.2019.02.223

rAAV mediated combined gene transfer and overexpression of TGF-beta and IGF-I in human bone marrow-derived mesenchymal stem cells upon implantation in a human osteochondral defect model.
2019 World Congress on Osteoarthritis (OARSI)
Internacional

Autores Morscheid, S, Venkatesan, JK, Rey-Rico, A, Schmitt, G, Madry, H, Cucchiarini, M
Organizador Osteoarthritis Research Society International (OARSI)
Lugar Toronto (Canadá)

Biological Effects of FGF-2 and IGF-I Co-Overexpression in Human Bone Marrow-Derived Mesenchymal Stem Cells via rAAV Vector Administration
21st Annual Meeting of the American-Society-of-Gene-and-Cell-Therapy (ASGCT)
Internacional

Autores Venkatesan, JK, Bohm, T, Rey-Rico, A, Schmitt, G, Madry, H, Cucchiarini, M
Lugar Chicago (Estados Unidos)

Genetic Modification of Human Bone Marrow Aspirates via Delivery of Raav Vectors Coated on Pnass-Grafted Poly(epsilon-Caprolactone) Scaffolds.
21st Annual Meeting of the American-Society-of-Gene-and-Cell-Therapy (ASGCT)
Internacional

Autores Venkatesan, JK, Leroux, A, Baumann, JS, Rey-Rico, A, Falentin-Daudre, C, Frisch, J, Madry, H, Migonney, V, Cucchiarini, M
Lugar Chicago (Estados Unidos)

rAAV SOX9 Gene Transfer Stimulates the Chondrogenic Differentiation Activities in Human Peripheral Blood Aspirates.
21st Annual Meeting of the American-Society-of-Gene-and-Cell-Therapy (ASGCT)
Internacional

Autores Venkatesan, JK, Orth, P, Rey-Rico, A, Schmitt, G, Madry, H, Cucchiarini, M
Lugar Chicago (Estados Unidos)

Dual FGF-2 and SOX9 gene transfer via rAAV vectors: effects on the chondrogenic and metabolic processes in human bone marrow aspirates.
2018 Osteoarthritis Research Society International (OARSI) World Congress
Internacional

Autores Tao, K, Rey-Rico, A, Venkatesan, JK, Schmitt, G, Madry, H, Cucchiarini, M
Lugar Liverpool (Reino Unido)

Controlled delivery of rAAV vectors via supramolecular polypseudorotaxane gels for cartilage tissue engineering approaches
2018 Annual Meeting of the Orthopaedic Research Society (ORS).
Internacional

Autores Rey-Rico, A, Venkatesan, JK, Schmitt, Gertrud, Concheiro, A, Madry, H, Alvarez-Lorenzo, C, Cucchiarini, M
Organizador Orthopaedic Research Society (ORS)
Lugar Nueva Orleans (Estados Unidos)

Influence of FGF-2 and SOX9 Overexpression via Recombinant Adeno-Associated Vector Gene Transfer on Human Bone Marrow-Derived Mesenchymal Stem Cells.
2018 Annual Meeting of the Orthopaedic Research Society (ORS).
Internacional

Autores Lerner, L, Venkatesan, JK, Rey-Rico, A, Schmitt, G, Madry, H, Cucchiarini, M
Organizador Orthopaedic Research Society (ORS)
Lugar Nueva Orleans (Estados Unidos)

PEO-PPO-PEO polymeric micelles as protective systems against inhibitors of rAAV-mediated gene transfer
2018 Annual Meeting of the Orthopaedic Research Society (ORS).
Internacional

Autores Rey-Rico, A, Venkatesan, JK, Schmitt, G, Concheiro, A, Madry, H, Alvarez-Lorenzo, C, Cucchiarini, M
Organizador Orthopaedic Research Society (ORS)
Lugar Nueva Orleans (Estados Unidos)

PEO-PPO-PEO micelles as effective rAAV-mediated delivery systems to overexpress SOX9 in human osteoarthritic articular chondrocytes
2018 Osteoarthritis Research Society International (OARSI) World Congress
Internacional

Autores Rey-Rico, A, Venkatesan, JK, Schmitt, G, Madry, H, Cucchiarini, M
Lugar Liverpool (Reino Unido)

Terapia xénica para a reparación de cartilaxe
XI JORNADA CIÉNTÍFICA EN TERAPIA CELLULAR Y MEDICINA REGENERATIVA
Internacional

Autores Rey-Rico, A
Lugar Coruña, A (España)

Terapia génica para la regeneración de cartílago
Programa de seminarios cientificos del Instituto de Investigación Biomedica de A Coruña (INIBIC)
Local

Autores Rey-Rico, A
Lugar Coruña, A (España)

Effective transduction of human articular chondrocytes in vitro and in a human osteochondral defect model via polymeric micelles.
2017 Deutscher Kongress für Orthopädie und Unfallchirurgie (DKOU)
Nacional

Autores Rey-Rico, A, Frisch, J, Venkatesan, JK, Schmitt, G, Rial-Hermida, I, Taboada, P, Concheiro, A, Madry, H, Alvarez-Lorenzo, C, Cucchiarini, M
Lugar Berlin (Alemania)

Inhibition of rAAV-mediated transduction of human mesenchymal stem cells in the presence of platelet rich plasma.
2017 Deutscher Kongress für Orthopädie und Unfallchirurgie (DKOU)
Nacional

Autores Rey-Rico, A, Venkatesan, JK, Müller, I, Frisch, J, Wildemann, B, Eichler, H, Madry, H, Cucchiarini, M
Lugar Berlin (Alemania)

Polypseudorotaxane gels as viral vectors release platforms for applications in cartilage regeneration
5th European Conference on Cyclodextrins
Internacional

Autores Rey-Rico, A, Babicz, H, Madry, H, Concheiro, A, Cucchiarini, M, Alvarez-Lorenzo, C
Organizador Universidade de Lisboa
Lugar Lisboa (Portugal)

rAAV-mediated modification of human articular chondrocytes via delivery in polymeric PEO-PPO-PEO micelles to overexpress TGF-ß.
Tissue Engineering and Regenerative Medicine International Society TERMIS ¿ EU conference
Internacional

Autores Rey-Rico, A, Frisch, J, Venkatesan, JK, Concheiro, A, Alvarez-Lorenzo, C, Madry, H, Cucchiarini, M
Lugar Davos (Suiza)

PEO-PPO-PEO micelles as effective rAAV-mediated delivery systems to overexpress TGF-ß in human osteoarthritic articular chondrocytes
20th Annual Meeting of the American Society of Gene & Cell Therapy (ASGCT)
Internacional

Autores Rey-Rico, A, Frisch, J, Venkatesan, JK, Concheiro, A, Alvarez-Lorenzo, C, Madry, H, Cucchiarini, M
Lugar Washington (Estados Unidos)

Durable rAAV-mediated gene transfer in human normal and osteoarthritic articular chondrocytes in three-dimensional culture conditions
2017 Annual Meeting of the Orthopaedic Research Society (ORS).
Internacional

Autores Mueller, O, Frisch, J, Rey-Rico, A, Venkatesan, JK, Schmitt, G, Madry, H, Cucchiarini, M
Organizador Orthopaedic Research Society (ORS).
Lugar San Diego (Estados Unidos)

Engineered cartilage tissue analogs based on human chondrocytes and the effects of gene-transfer via rAAV.
2017 Annual Meeting of the Orthopaedic Research Society (ORS).
Internacional

Autores Mueller, O, Frisch, J, Rey-Rico, A, Venkatesan, JK, Schmitt, G, Madry, H, Cucchiarini M.
Organizador Orthopaedic Research Society (ORS).
Lugar San Diego (Estados Unidos)

Genetic Modification of human bone marrow aspirates via delivery of rAAV vectors coated on PNaSS-grafted poly(epsilon-caprolactone) scaffolds
2017 Annual Meeting of the Orthopaedic Research Society (ORS).
Internacional

Autores Venkatesan, JK, Leroux, A, Baumann, A, Rey-Rico, A, Falentin-Daudré, J, Frisch, J, Madry, H, Migonney, V, Cucchiarini, M
Organizador Orthopaedic Research Society (ORS).
Lugar San Diego (Estados Unidos)

Interference of platelet rich plasma with gene transfer via rAAV vectors in human bone marrow-derived mesenchymal stem cells
2017 Annual Meeting of the Orthopaedic Research Society (ORS).
Internacional

Autores Venkatesan, JK, Rey-Rico, A, Müller, I, Frisch, J, Wildemann, B, Eichler, H, Madry, H, Cucchiarini, M
Organizador Orthopaedic Research Society (ORS).
Lugar San Diego (Estados Unidos)

Overexpression of human DKK1 via rAAV stimulates the chondrogenic differentiation processes in human bone marrow-derived mesenchymal stem cells
2017 Annual Meeting of the Orthopaedic Research Society (ORS).
Internacional

Autores Venkatesan, JK, Rey-Rico, A, Frisch, J, Madry, H, Cucchiarini, M
Organizador Orthopaedic Research Society (ORS).
Lugar San Diego (Estados Unidos)

PEO-PPO-PEO Micelles As rAAV Carriers For Effective Transduction Of Human Articular Chondrocytes In Vitro And In A Human Osteochondral Defect Model
2017 Annual Meeting of the Orthopaedic Research Society (ORS).
Internacional

Autores Rey-Rico, A, Frisch, J, Venkatesan, JK, Schmitt, G, Rial-Hermida, I, Taboada, P, Concheiro, A, Madry, H, Alvarez-Lorenzo, C, Cucchiarini, M
Organizador Orthopaedic Research Society (ORS).
Lugar San Diego (Estados Unidos)

Recombinant adeno-associated virus mediated cooverexpression of transforming growth factor beta and SOX9 genes enhace the metabolic and chondrogenic activities in human bone marrow aspirates.
2017 World Congress on Osteoarthritis (OARSI)
Internacional

Autores Ke, T, Rey-Rico, A, Frisch, J, Venkatesan, JK, Schmitt, G, Madry, H, Lin, J, Cucchiarini, M
Organizador 2018 World Congress on Osteoarthritis (OARSI)
Lugar Las Vegas (Estados Unidos)
DOI https://doi.org/10.1016/j.joca.2017.02.733

Evaluation of chondrogenesis in human bone marrow aspirates upon rAAV-mediated FGF-2 gene transfer and overexpression
2016 Deutscher Kongress für Orthopädie und Unfallchirurgie (DKOU)
Nacional

Autores Frisch, J, Rey-Rico, A, Venkatesan, JK, Schmitt, G, Madry, H, Cucchiarini, M
Lugar Berlin (Alemania)

Overexpression of TGF-ß via rAAV gene transfer stimulates the chondrogenic processes in human bone marrow aspirates.
2016 Deutscher Kongress für Orthopädie und Unfallchirurgie (DKOU)
Nacional

Autores Frisch, J, Rey-Rico, A, Venkatesan, JK, Schmitt, G, Madry, H, Cucchiarini, M
Lugar Berlin (Alemania)

PEO-PPO-PEO micelles as effective rAAV-mediated delivery systems to target human mesenchymal stem cells without altering their differentiation potency.
2016 Deutscher Kongress für Orthopädie und Unfallchirurgie (DKOU)
Nacional

Autores Rey-Rico, A, Venkatesan, JK, Frisch, J, Rial-Hermida, I, Concheiro, A, Madry, H, Alvarez-Lorenzo, C, Cucchiarini, M
Lugar Berlin (Alemania)

Remodeling human osteoarthritic articular cartilage rAAV-mediated via combined gene transfer and overexpression of TGF-beta and sox9
2016 Deutscher Kongress für Orthopädie und Unfallchirurgie (DKOU)
Nacional

Autores Ke, T, Frisch, J, Rey-Rico, A, Venkatesan, JK, Schmitt, G, Madry, H, Lin, JH, Cucchiarini, M
Lugar Berlin (Alemania)

rAAV-mediated sox9 overexpression induces chondrogenesis in human bone marrow aspirates seeded in woven poly(¿-caprolactone) scaffolds
2016 Deutscher Kongress für Orthopädie und Unfallchirurgie (DKOU)
Nacional

Autores Venkatesan, JK, Moutos, F, Rey-Rico, A, Frisch, J, Schmitt, G, Guilak, F, Madry, H, Cucchiarini, M
Lugar Berlin (Alemania)

PEO-PPO-PEO micelles as new, effective rAAV-mediated gene delivery systems to modify human mesenchymal stem cells without altering their differentiation potency.
Les Journées Françaises de Biologie des Tissus Minéralisés (JFBTM)
Nacional

Autores Rey-Rico, Ana, Frisch, J, Venkatesan, JK, Rial-Hermida, I, Concheiro, A, Madry, H, Cucchiarini, M
Organizador Universidad de Lorraine
Lugar Nancy (Francia)

Comparative evaluation of the genetic modification of human and murine musculoskeletal cells via rAAV vectors in vitro and ex situ.
2016 Annual Meeting of the Orthopaedic Research Society (ORS).
Internacional

Autores Daamouch, S, Rey-Rico, A, Frisch, J, Venkatesan, JK, Laschke, MW, Madry, H, Reboul, P, Cucchiarini, M
Organizador Orthopaedic Research Society (ORS)
Lugar Orlando (Estados Unidos)

Effective rAAV-mediated Transduction Of Human Articular Chondrocytes Via Polymeric PEO-PPO-PEO Micelles In Vitro And In An Experimental Model Of Osteochondral Defect In Situ
2016 Annual Meeting of the Orthopaedic Research Society (ORS).
Internacional

Autores Rey-Rico, A, Frisch, J, Venkatesan, JK, Concheiro, A, Madry, H, Alvarez-Lorenzo, C, Cucchiarini, M
Organizador Orthopaedic Research Society (ORS)
Lugar Orlando (Estados Unidos)

Enhanced Proteoglycan Production of Primary Human Meniscal Fibrochondrocytes Cultivated in Biomedical-Grade, High Mannuronic Acid Content (BioMVM) Alginate 3-D Hydrogel Culture
2016 Annual Meeting of the Orthopaedic Research Society (ORS).
Internacional

Autores Rey-Rico, A, Klich, A, Cucchiarini, M, Madry, H
Organizador Orthopaedic Research Society (ORS)
Lugar Orlando (Estados Unidos)

Evaluation Of Chondrogenesis In Human Bone Marrow Aspirates Upon rAAV mediated FGF-2 Gene Transfer And Overexpression
2016 Annual Meeting of the Orthopaedic Research Society (ORS).
Internacional

Autores Frisch, J, Rey-Rico, A, Venkatesan, JK, Schmitt, G, Madry, H, Cucchiarini, M
Organizador Orthopaedic Research Society (ORS)
Lugar Orlando (Estados Unidos)

Manipulation Of Peripheral Blood Aspirates Via rAAV To Improve Cartilage Repair
2016 Annual Meeting of the Orthopaedic Research Society (ORS).
Internacional

Autores Frisch, J, Venkatesan, JK, Rey-Rico, A, Orth, P, Schmitt, G, Madry, H, Cucchiarini, M
Organizador Orthopaedic Research Society (ORS)
Lugar Orlando (Estados Unidos)

Overexpression Of TGFß Via rAAV Gene Transfer Stimulates The Chondrogenic Processes In Human Bone Marrow Aspirates
2016 Annual Meeting of the Orthopaedic Research Society (ORS).
Internacional

Autores Frisch, J, Rey-Rico, A, Venkatesan, JK, Schmitt, G, Madry, H, Cucchiarini, M
Organizador Orthopaedic Research Society (ORS)
Lugar Orlando (Estados Unidos)

PEO-PPO-PEO Micelles As Effective rAAV-mediated Delivery Systems To Genetically Modify Human Mesenchymal Stem Cells Without Altering Their Differentiation Potency
2016 Annual Meeting of the Orthopaedic Research Society (ORS).
Internacional

Autores Rey-Rico, A, Venkatesan, JK, Frisch, J, Rial-Hermida, I, Concheiro, A, Madry, H, Alvarez-Lorenzo, C, Cucchiarini, M
Organizador Orthopaedic Research Society (ORS)
Lugar Orlando (Estados Unidos)

rAAV-mediated SOX9 Overexpression Induces Chondrogenesis In Human Bone Marrow Aspirates Seeded In Woven Poly(¿-caprolactone) Scaffolds
2016 Annual Meeting of the Orthopaedic Research Society (ORS).
Internacional

Autores Venkatesan, JK, Moutos, F, Rey-Rico, A, Frisch, J, Schmitt, G, Guilak, F, Madry, H, Cucchiarini, M
Organizador Orthopaedic Research Society (ORS)
Lugar Orlando (Estados Unidos)

Controlled release of adeno-associated viral vectors (rAAV) from self-assembling peptide hydrogels to genetically modify human mesenchymal stem cells
IX Internacional Forum on Advances in Pharmaceutical Technology (CISDEM)
Nacional

Autores Rey-Rico, A, Venkatesan, JK, Frisch, J, Schmitt, G, Mata, A, Semino, C, Madry, H, Cucchiarini, M
Organizador Facultade de Farmacia
Lugar Santiago de Compostela (España)

Chondrogene Differenzierung genetisch modifizierter hMSCs mittels kontrollierter Freisetzung von rAAV-Vektoren aus selbstorganisierenden Peptid-Hydrogelen
2015 Deutscher Kongress für Orthopädie und Unfallchirurgie (DKOU)
Nacional

Autores Rey-Rico, A, Venkatesan, JK, Frisch, J, Monge Marcet, A, Mata, A, Semino, C, Madry, H, Cucchiarini, M
Lugar Berlín (Alemania)

Effekte statischer und dynamischer Kulturbedingungen auf daschondrogene Differenzierungspotential humaner Knochenmarkaspiratenach rAAV-vermittelter Überexpression von sox9.
2015 Deutscher Kongress für Orthopädie und Unfallchirurgie (DKOU)
Nacional

Autores Venkatesan, JK, Rey-Rico, A, Frisch, J, Schmitt, G, Madry, H, Cucchiarini, M
Lugar Berlín (Alemania)

Kontrollierte Freisetzung von rekombinanten adeno-assoziierten viralen (rAAV) Vektoren aus Alginat-Poloxamer Komplexsystemen
2015 Deutscher Kongress für Orthopädie und Unfallchirurgie (DKOU)
Nacional

Autores Rey-Rico, A, Diaz-Rodriguez, P, Madry, H, Landin, M, Cucchiarini, M
Lugar Berlín (Alemania)

Verbesserte chondrogene Differenzierung in Knochenmarkaspiraten von Minischweinen nach rAAV-vermitteltem Gentransfer mit anschließender Überexpression des Transkriptionsfaktors sox9
2015 Deutscher Kongress für Orthopädie und Unfallchirurgie (DKOU)
Nacional

Autores Frisch, J, Rey-Rico, A, Venkatesan, JK, Schmitt, G, Madry, H, Cucchiarini, M
Lugar Berlín (Alemania)

Vorteile der Nutzung von PEO-PPO Copolymeren für effektiven Gentransfer in humane, aus Knochnemark isolierte mesenchymale Stammzellen mittels rAAV-Vektoren
2015 Deutscher Kongress für Orthopädie und Unfallchirurgie (DKOU)
Nacional

Autores Rey-Rico, A, Alvarez-Lorenzo, C, Concheiro, A, Madry, H, Cucchiarini, M
Lugar Berlín (Alemania)

rAAV-basierte genetische Modifikation von humanen Knochenmarkaspiraten, eingebettet in gewebte 3D Poly(Epsilon-Caprolacton) Scaffolds
2015 Deutscher Kongress für Orthopädie und Unfallchirurgie (DKOU)
Nacional

Autores Cucchiarini, M, Frisch, J, Rey-Rico, A, Venkatesan, JK, Schmitt, G, Madry, H, Cucchiarini, M
Lugar Berlín (Alemania)

rAAV-vermittelte Überexpression von IGF-I und ihr Einfluss auf die chondrogene Differenzierung von humanen Knochenmarkaspiraten.
2015 Deutscher Kongress für Orthopädie und Unfallchirurgie (DKOU)
Nacional

Autores Frisch, J, Rey-Rico, A, Venkatesan, JK, Schmitt, G, Madry, H, Cucchiarini, M
Lugar Berlín (Alemania)

Enhanced chondrogenic differentiation of human osteoarthritic bone marrow aspirates modified to overexpress the transcription factor SOX9 via rAAV-mediated gene transfer in dynamic versus static culture conditions
2015 Osteoarthritis Research Society International (OARSI) World Congress
Internacional

Autores Venkatesan, JK, Rey-Rico, A, Frisch, J, Madry, H, Cucchiarini, M
Lugar Seattle (Estados Unidos)
DOI https://doi.org/10.1016/j.joca.2015.02.672

Benefits of biomedical versus nonbiomedical grade alginates for the durable and safe modification of hMSC via rAAV-mediated gene transfer.
2015 Annual Meeting of the Orthopaedic Research Society (ORS).
Internacional

Autores Hunneshagen, C, Rey-Rico, A, Madry, H, Cucchiarini, M
Organizador Orthopaedic Research Society (ORS)
Lugar Las Vegas (Estados Unidos)

Controlled release of rAAV vectors from alginate-poloxamer complex systems
2015 Annual Meeting of the Orthopaedic Research Society (ORS).
Internacional

Autores Diaz-Rodriguez, P, Rey-Rico, A, Madry, H, Landin, M, Cucchiarini, M
Organizador Orthopaedic Research Society (ORS)
Lugar Las Vegas (Estados Unidos)

Benefits of using PEO-PPO copolymers for the effective delivery of rAAV vectors in human bone marrow-derived mesenchymal stem cells
2015 Annual Meeting of the Orthopaedic Research Society (ORS).
Internacional

Autores Rey-Rico, A, Alvarez-Lorenzo, C, Concheiro, A, Madry, H, Cucchiarini, M
Organizador Orthopaedic Research Society (ORS)
Lugar Las Vegas (Estados Unidos)

Chondrogenic differentiation of genetically modified hMSC via controlled release of rAAV vectors from self-assembling peptide hydrogels
2015 Annual Meeting of the Orthopaedic Research Society (ORS).
Internacional

Autores Rey-Rico, A, Venkatesan, JK, Frisch, J, Schmitt, G, Monge Marcet, A, Mata, A, Semino, C, Madry, H, Cucchiarini, M
Organizador Orthopaedic Research Society (ORS)
Lugar Las Vegas (Estados Unidos)

Effects of rAAV Sox9 gene transfer upon the chondrogenic differentiation of hMSCs seeded in polyurethane scaffolds
2015 Annual Meeting of the Orthopaedic Research Society (ORS).
Internacional

Autores Venkatesan, JK, Rey-Rico, A, Gardner, O, Schmitt, G, Alini, M, Stoddart, M, Cucchiarini, M, Madry, H
Organizador Orthopaedic Research Society (ORS)
Lugar Las Vegas (Estados Unidos)

Effects of static versus dynamic culture conditions upon the chondrogenic differentiation potential of human bone marrow aspirates following rAAV-mediated overexpression of Sox9
2015 Annual Meeting of the Orthopaedic Research Society (ORS).
Internacional

Autores Venkatesan, JK, Rey-Rico, A, Frisch, J, Schmitt, G, Madry, H, Cucchiarini, M
Organizador Orthopaedic Research Society (ORS)
Lugar Las Vegas (Estados Unidos)

Enhanced chondrogenic differentiation processes in bone marrow aspirates from minipigs following rAAV-mediated gene transfer and overexpression of the transcription factor Sox9
2015 Annual Meeting of the Orthopaedic Research Society (ORS).
Internacional

Autores Frisch, J, Rey-Rico, A, Venkatesan, JK, Schmitt, G, Cucchiarini, M, Madry, H
Organizador Orthopaedic Research Society (ORS)
Lugar Las Vegas (Estados Unidos)

Improved conditions to enhance the chondrogenic differentiation processes in human primary bone marrow aspirates via rAAV-mediated gene transfer.
2015 Annual Meeting of the Orthopaedic Research Society (ORS).
Internacional

Autores Rey-Rico, A, Frisch, J, Venkatesan, JK, Schmitt, G, Madry, H, Cucchiarini, M
Organizador Orthopaedic Research Society (ORS)
Lugar Las Vegas (Estados Unidos)

Influence of IGF-I overexpression via rAAV gene transfer upon the chondrogenic differentiation potential of human bone marrow aspirates
2015 Annual Meeting of the Orthopaedic Research Society (ORS).
Internacional

Autores Frisch, J, Rey-Rico, A, Venkatesan, JK, Schmitt, G, Cucchiarini, M, Madry, H
Organizador Orthopaedic Research Society (ORS)
Lugar Las Vegas (Estados Unidos)

rAAV-based genetic modification of human bone marrow aspirates seeded in 3D woven poly(epsilon-caprolactone) (PCL) scaffolds.
2015 Annual Meeting of the Orthopaedic Research Society (ORS).
Internacional

Autores Frisch, J, Rey-Rico, A, Venkatesan, JK, Moutos, F, Schmitt, G, Guilak, F, Madry, H, Cucchiarini, M
Organizador Orthopaedic Research Society (ORS)
Lugar Las Vegas (Estados Unidos)

Enhanced Chondrogenic Potential of Human Bone Marrow Aspirates Upon rAAV-Mediated Overexpression of IGF-I
18th Annual Meeting of the American Society (ASGCT)
Internacional

Autores Frisch, J, Rey-Rico, A, Venkatesan, JK, Madry, H, Cucchiarini, M
Lugar Nueva Orleans (Estados Unidos)
DOI https://doi.org/10.1016/s1525-0016(16)34014-x

Effects of IGF-I overexpression on the chondrogenic potential of human bone marrow aspirates modified via rAAV gene transfer
2015 World Congress on Osteoarthritis (OARSI)
Internacional

Autores Frisch, J, Rey-Rico, A, Venkatesan, JK, Madry, H, Cucchiarini, M
Organizador Osteoarthitis Research Society International (OARSI)
Lugar Seattle (Estados Unidos)
DOI https://doi.org/10.1016/j.joca.2015.02.673

Effects of exosomes compared with autologous conditioned serum upon the metabolic activities of human osteoarthritic articular cartilage in situ
2015 World Congress on Osteoarthritis (OARSI)
Internacional

Autores Rey-Rico, A, Reinecke, J, Wehling, P, Cucchiarini, M, Madry, H
Organizador Osteoarthitis Research Society International (OARSI)
Lugar Seattle (Estados Unidos)
DOI https://doi.org/10.1016/j.joca.2015.02.736

TGF-beta1-freisetzende Poly(Ether-Ester)-Multiblock-Scaffolds ermöglichen eine effiziente chondrogene Differenzierung von humanen mesenchymalen Stammzellen.
2014 Deutscher Kongress für Orthopädie und Unfallchirurgie (DKOU)
Nacional

Autores Rey-Rico, A, Venkatesan, JK, Sohier, J, Schmitt, G, Moroni, L, Cucchiarini, M, Madry, H
Lugar Berlín (Alemania)

TGF-beta1-releasing poly(ether-ester) multiblock scaffolds lead to efficient chondrogenic differentiation of human mesenchymal stem cells.
2014 Annual Meeting of the Orthopaedic Research Society (ORS)
Internacional

Autores Rey-Rico, A, Venkatesan, JK, Sohier, J, Moroni, L, Cucchiarini, M, Madry, H
Organizador Orthopaedic Research Society (ORS)
Lugar Nueva Orleans (Estados Unidos)

Efficacy and stability of gene transfer via rAAV in human bone marrow aspirates -a comparative analysis in dynamic versus static culture conditions
2014 Annual Meeting of the Orthopaedic Research Society (ORS)
Internacional

Autores Venkatesan, JK, Rey-Rico, A, Schmitt, G, Madry, H, Cucchiarini, M
Organizador Orthopaedic Research Society (ORS)
Lugar Nueva Orleans (Estados Unidos)

Evaluation of controlled release of rAAV vectors using self-assembling peptide hydrogels.
2014 Annual Meeting of the Orthopaedic Research Society (ORS)
Internacional

Autores Rey-Rico, A, Venkatesan, JK, Schmitt, G, Monge-Marcet, A, Mata, A, Semino, C, Madry, H, Cucchiarini, M
Organizador Orthopaedic Research Society (ORS)
Lugar Nueva Orleans (Estados Unidos)