PhD Miguel Ángel Maestro Saavedra  

Design, Synthesis, Evaluation and Structure of Allenic 1¿,25-Dihydroxyvitamin D3 Analogs with Locked Mobility at C-17

Innovative three-step microwave-promoted synthesis of N-propargyltetrahydroquinoline and 1,2,3-triazole derivatives as a potential factor Xa (FXa) inhibitors: drug design, synthesis and biological evaluation

Microwave-mediated synthesis of N-allyl/propargyl derivatives: enzymatic analysis as a potential factor Xa (FXa) inhibitor, theoretical and computational molecular docking

Vitamin D and Its Synthetic Analogs

Mechanistic insights for the transprotection of tertiary amines with Boc2O via charged carbamates: access to both enantiomers of 2-azanorbornane-3-exo-carboxylic acids

Stereoselective synthesis of 25S,26-dihydroxyvitamin D3

Stereoselective Palladium¿Catalyzed Approach to Vitamin D3 Derivatives in Protic Medium

Synthesis of Side-Chain Locked Analogs of 1¿,25-Dihydroxyvitamin D3 Bearing a C17 Methyl Group

Aromatic-Based Design of Highly Active and Noncalcemic Vitamin D Receptor Agonists

Total synthesis of 1¿,25-dihydroxyvitamin D3 analogs modified at the side chain and D-ring

Total synthesis of 1¿,25-dihydroxyvitamin D3 (calcitriol) through a Si-assisted allylic substitution

A new approach to 19-nor-A-ring phosphine oxide for the convergent synthesis of 19-nor-calcitriol

1ß,25-Dihydroxyvitamin D3: A new vitamin D metabolite in human serum.

Stereoselective synthesis of 1ß,25-Dihydroxyvitamin D3 and its 26,27-hexadeuterated derivative.

Carborane-based design of a potent vitamin Dreceptor agonist

Vitamin D receptor 2016: novel ligands and structural insights.

Quantitative analytical method to evaluate the metabolism of vitamin D

Pit-1 inhibits BRCA1 and sensitizes human breast tumors to cisplatin and vitamin D treatment

Synthesis of nonadeuterated 1a,25-dihydroxyvitamin D2

A Chiral N(H)-tBu and N(H)-Ad NiII Complexes of Glycine Schiff Bases:Deduction of a Mode of Kinetic Diastereoselectivity

Clinical utility of simultaneous quantitation of 25-hydroxyvitamin D and 24,25-dihydroxyvitamin D by LC-MS/MS involving derivatization with DMEQ-TAD

Synthesis, crystal structures, antimicrobial activities, and DFT calculations of two new azido nickel(II) complexes

Endo-benzonorbornen-2-ol as an efficient non-natural chiral auxiliary in the asymmetric aza-Diels-Alder reactions between cyclopentadiene and (1-phenylethyl)iminoacetates

An Efficient Convergent Synthesis of 1a,25-dihydroxy-3-epi-vitamin D2

Chiral N(H)-tBu and N(H)-Ad NiII complexes of Glycine Schiff Bases: Deduction of a Mode of Kinetic Diastereoselectivity

Gold catalyzed stereoselective tandem hydroamination¿formal aza-Diels¿Alder reaction of propargylic amino esters

Gold-Catalyzed Intramolecular Hydroamination of o-Alkynylbenzyl Carbamates: A Route to Chiral Fluorinated Isoindoline and Isoquinoline Derivatives

A efficient synthesis of 1a,25-dihydroxy-20-epi-vitamin D3

Base-Dependent Stereodivergent Intramolecular Aza-Michael Reaction: Asymmetric Synthesis of 1,3-Disubstituted Isoindolines

An Approach to 2,4-Substituted Pyrazolo[1,5-a|pyridines and Pyrazolo[1,5-a|azepines by Ring-Closing Metathesis

A novel VIVO-pyrimidinone complex: synthesis, solution speciation and human serum protein binding

Design, Synthesis, Evaluation, and Structure of Vitamin D Analogues with Furan Side Chains

Dinuclear MnIII Compounds [{Mn(bpy)(H2O)}2(¿-4-RC6H4COO)2(¿-O)](NO3)2 (R = Me, F, CF3, MeO, tBu): Effect of the R Group on the Magnetic Properties and the Catalase Activity

Aliphatic Dicarboxylate Ligands Assemble Weakly Coupled Molecular Pairs of [MnIII]2 Units

Synthesis and Biological Evaluation of 1¿,25-Dihydroxyvitamin D3 Analogues with a Long Side Chain at C12 and Short C17 Side Chain

Enantio- and Diastereoselective Organocatalytic ¿-Alkylation of Aldehydes with 3-Substituted 2-(Bromomethyl)acrylates

Synthesis of (1a)-1,25-Dihydroxyvitamin D3 with a ß-Positioned Seven-Carbon Side Chain at C(12)

Synthesis, Structure, and Biological Activity of des-Side Chain Analogues of 1 alpha,25-Dihydroxyvitamin D-3 with Substituents at C18

Synthesis and characterization of metallodendritic palladium-biscarbene complexes derived from 1,1 ¿-methylenebis(1,2,4-triazole)

Intramolecular Michael Reaction of tert-Butylsulfinyl Ketimines: Asymmetric Synthesis of 3-Substituted Indanones

Synthesis, crystal structure and magnetic properties of new dinuclear Mn(III) compounds with 4-ClC6H4COO and 4-BrC6H4COO bridges

Enantio- and Diastereoselective Organocatalytic ¿-Alkylation of Aldehydes with 3-Substituted 2-(Bromomethyl)acrylates

A 4-Hydroxypyrrolidine-Catalyzed Mannich Reaction of Aldehydes: Control of anti-Selectivity by Hydrogen Bonding Assisted by Bronsted Acids

A short practical approach to 24R,25-dihydroxyvitamin D3

Better Performance of Monodentate P-Stereogenic Phosphanes Compared to Bidentate Analogues in Pd-Catalyzed Asymmetric Allylic Alkylations

X-ray Diffraction, Solution Structure, and Computational Studies on Derivatives of (3-sec-Butyl-2,3-dihydro-1H-isoquinolin-4-ylidene)acetic Acid: Compounds with Activity as Calpain Inhibitors

(1,3,4-Oxadiazole)copper(II) Compounds: Dimensionality, Magnetism and Nuclease Activity

Conjugate Addition of Nitroalkanes to an Acrylate Equivalent. Activation Stereocontrol at C-a of the Nitro Group through Double Catalytic Nuclease Activity

Highly Enantioselective Conjugate Additions of Aldehydes to Vinyl Sulfones

Synthesis and characterization of Ru(arene) complexes of bispyrazolylazines: Catalytic hydrogen transfer of ketones

Self-assembly of Ligands Designed for the Building of a New Type of [2 x 2] Metallic Grid. Anion Encapsulation and Diffusion NMR Spectroscopy

Structure, magnetic properties and nuclease activity of pyridine-2- carbaldehydethiosemicarbazonecopper(II) complexes

(Arene)ruthenium(II) complexes containing substituted bis(pyrazolyl)methane ligands - catalytic behaviour in transfer hydrogenation of ketones

Highly condensed cyclic carbohydrates derived from a common precursor

New dinuclear MnIII compounds with 2-MeC6H4COO and 2- FC6H4COO bridges - effect of terminal monodentate ligands (H2O, ClO4- and NO3-) on the magnetic properties

PuPHOS and CamPHOS Ligands in the Intermolecular Catalytic Pauson-Khand Reaction

Synthesis and catalytic applications of C1 symmetric group 4 ansa- metallocene complexes

Synthesis of two carboxylic haptens for raising antibodies to 25-Hydroxyvitamin D3 and 1á,25-Dihydroxyvitamin D3

Synthesis, Crystal Structure, and Magnetic Studies of Oxo-Centered Trinuclear Chromium(III) Complexes: [Cr3(u3-O)(u2- PhCOO)6(H2O)3]NO3·4H2O·2CH3OH, a Case of Spin-Frustrated System, and ...

Boron Trifluoride-Induced, New Stereospecific Rearrangements of Chiral Epoxy Ethers. Ready Access to Enanatiopure 4-(Diarylmethyl)-1,3-dioxolanes and 4,5-Disubstituted Tetrahydrobenzo[c]oxepin-4-ols

C-H...O Hydrogen bond-directed ligand exchange reaction: Diastereoselective synthesis of P,S-Bridged (-alkyne) Co2 (CO)4 Complexes

Combined Effects of Diamines and Carboxylate Bridges on Structural and Magnetic Properties of a Series of Polynuclear Copper(II) Complexes with 1,1-Cyclobutanedicarboxylic Acid

Gold-ruthenium compounds containing bridging phospideor thiolate groups: Crystal structures of the intermediate spacies [Ru3(CO)8L_3-n2,.n4,n3-{Me3SiCC(C2Fc)SC(Fc)CSC=CSiMe

One Dimensional 3d-4f Heterometallic Compounds: Synthesis, Structure and Magentic Properties

Synthesis, Crystal Structure and Magnetic Studies of One-Dimensional Cyano-Bridged Ln3+-Cr3+ Complexes with bpy as a Blocking Ligand

Allylic Alkylations Catalyzed by Palladium Systems Containing Modular Chiral Dithioethers. A Structural Study of the Allylic Intermediates

Allylpalladium Complexes with P-Stereogenic Monodentate Phosphines. Application in the Asymmetric Hydrovinylation of Styrene

Magnetic Properties of Cyano-Bridged Ln3+-M3+ Complexes. Part I: Trinuclear Complexes (Ln3+ = La, Ce, Pr, Nd, Sm; M3+ = FeLS, Co) with bpy as Blocking Ligand

Magnetism of Cyano-Bridged Ln3+-M3+ Complexes. Part II: One-Dimensional Complexes (Ln3+ = Eu, Tb, Dy, Ho, Er, Tm; M3+ Fe or Co) with bpy as Blocking Ligand

Oxazoline-mediated interannular cyclopalladation of ferrocene: Chiral palladium(II) catalysts for the enantioselective aza-Claisen rearrangement

Pd-Catalyzed Carbocyclization-Neghishi Croos-Coupling Cascade: A Novel Approach to 1?,25-Dihydroxyvitamin D3 and Analogues

Phosphine-Substrate Recognition through the C-H...O Hydrogen Bond: Application to the Asymmetric Pauson-Khand Reaction

Ruthenium complexes containing chiral N-donor ligands as catalysts in acetophenone hydrogen transfer - new amino effect on enantioselectivity

Synthesis and reactivity of iron carbonyl clusters containing alkynethiolate ligands

Synthesis, hydrosilylation reactivity and catalytic properties of group 4 ansa-metallocene complexes

Unexpected behaviour of pyridine-2-carbaldehyde thiosemicarbazonatocopper(II) entities in aqueous basic medium - partial transformation of thioamide into nitrile

8-Aryl substituted boron-dipyrromethene dyes: crystal structures and computational studies

An Unprecedented Hybrid Scorpionate/Cyclopentandienyl Ligand

Crystallization-induced dynamic resolution and analysis of the non-covalent interactions in the crystal packing of peptide-biphenyl hybrids

Diastereo- and enantioselective synthesis of novel beta-lactam-containing 1,4-benzodiazepines through a ketene-imine cycloaddition reaction

Dioxomolybdenum(VI) thionates: molecular structure of dioxobis(pyridine-2-thiolate-N,S)molybdenum(VI).

Exo- and Endocyclic Oxazolinyl-Phosphane Palladium Complexes: Catalytic Behavior in Allylic Alkylation Processes

New Synthon in the Design of ansa-Cyclopentadienyl Ligands with Variable Substitution at the Bridging Atom

PuPHOS: A Synthetically Useful Chiral Bidentate Ligand for the Intermolecular Pauson-Khand Reaction

Ruthenium Arene Derivative with PN Hemilabile Ligands, P-C Cleaveage and Phosphine to Phosphite Transformation

Stereoselectivity in the intermolecular Pauson-Khand reaction of electron-deficient terminal alkynes

Structural studies of mono- and dimetallic MoVI complexes - a new mechanistic contribution in catalytic olefin epoxidation provided by oxazoline ligands

Synthesis and structure of new (polyphosphane)ruthenium complexes with the hemilabile ligand 2-(diphenylphosphanyl)-1-methyl-1H-imidazole - An unexpected rearrangement of [RuCl2(PN)(PPh3)2]

Heck-mediated synthesis and photochemically induced cyclization of [2-(2-styrylphenyl)ethyl]carbamic acid ethyl esters and 2-styrylbenzoic acid methyl esters: total synthesis of naphtho[2,1f]isoquinol

New 1,3,4-oxadiazolecopper(II) derivatives obtained from thiosemicarbazone complexes

Equilibria between Metallosupramolecular Squares and Triangles with the New Rigid Linker 1,4-Bis(4-pyridyl)tetrafluorobenzene. Experimental and Theoretical Study of the Structural Dependence of NMR Da

Magnetism of Cyano-Bridged Hetero-One-Dimensional Ln3+-M3+ Complexes (Ln3+ = Sm, Gd, Yb; M3+ = FeLS, Co)

Coordination modes in a (thiosemicarbazone)copper(II)/oxalato system - structures of [{Cu(L)}2(ox)]2H2O, [Cu(HL)(ox)(H2O)], [{Cu(HL)}2(ox)][Cu(ox)2]2H2O and [{Cu(HL)}2(ox)](NO3)2 - Ferro- vs. antiferr

Iron carbonyl complexes of heterocyclic -diimines: systematic synthesis, crystal structures of [Fe(CO)3(L)] and [Fe2(CO)7(L)] (L = 2,2-bipyridine and 1,10-phenanthroline), and their AIM analysis

Synthesis of polyhydroxylated -nitrocyclohexane carboxylic acids derived from D-glucose: a striking case of racemization

Oxamato-Bridged Trinuclear NiIICuIINiII Complexes: A New (NiIICuIINiII)2 Hexanuclear Complex and Supramolecular Structures. Characterization and Magnetic Properties

First end-to-end thiocyanato chain containing 5-coordinate copper(II) ions

Design of New Hemilabile (P,S) Ligands for the Highly Diastereoselective Coordination to Alkyne Dicobalt Complexes: Application to the Asymmetric Intermolecular Pauson-Khand Reaction

Synthesis and Characterization of Heterodinuclear Ln3+-Fe3+ and Ln3+-Co3+ Complexes, Bridged by Cyanide Ligand (Ln3+ = Lanthanide Ions). Nature of the Magnetic Interaction in the Ln3+-Fe3+ Complexes

Synthesis of polyhydroxylated alfa-nitrocyclohexane carboxylic acids derived from D-glucose: a striking case of racemization.

Uranyl polyhalides, molecular structure of [UO2(OAsPh3)4](Br3)2 and [UO2(OPPh3)4](I3)2

Variety in the coordination models of the ligand hexakis (Pyrazol-1-yl) bencene (Hpzb) to Pd(II) and Cu(I) centres

Determination of total and dissolved phosphorus in agricultural runoff samples by inductively coupled plasma mass spectrometry

New Oxamidato-Bridged cull-nill complexed: supramolecular structures with thiocyanate ligands and hidrogen bonds. Magnetostructural studies: DFT Calculations.

Assessment of four inter-comparison exercises in inorganic elemental analysis

Syntesis, crystal structure and spectroscopic propierties of copper (II) complexes derivved from 2-methylamino-5-pyridin-2-yl-1,3,4-oxadiazole.

New oxamato-bridged Trinuclear cull-cull-cull complexes with hydrogen-bond supramolecular structures: syntesis and magneto-structural studies.

Polynuclear Mnll complexes with choroacetate bridge-sinthesis, estructure and magnetic properties.

Influence of quadrupolar interactions on the crystal packing of organic compaunds: the pentafluorophenyl ester of a tricyclic a,b-unsaturated-y-amino acid

Addition compounds of MoO2Br2 from MoO2Br2(H2O)2. Molecular Structure of MoO2Br2{COP[N(CH3)2]3}2 and MoO2BR2{CH2[P(O)(C6H5)2]2}

Synthesis, characterización, and magnetic properties of new complexes based on sefl-assembled homotrinuclear units cull-cull-cull

Reversing the stereoselectivity of the intermolecular Pauson Khand reaction: formation of endo-fused norbornadiene adducts

Evidence of desulfurization in the oxidative cyclization of thiosemicabazones. Conversion to 1,3,4-oxadiazole derivatives

Synthesis and characterization of [Cu(Me2oxpn)Ni(NO2)(tmen)](ClO4): a single ferrimagnetic dinuclear cull-Nill complex acting as weak molecule-based magnet

Bis(oxazoline) ligands containing four and five spacer atoms: palladium organometallic behavior

B-ferrocenyl-b-amino alcohols: a new class of central chiral forecene derivatives

Outer-spere addition compounds of MoO2Br2(H2O)2 with ethers. Molecular structure of MoO2Br2(H2O)2L (L=2,5,8-troxanonane, 2,5,8,11,14-pentaoxapentadecane)

Synthesis of novel optically pure quinolyl-b-amino-amino alcohol derivatives from oxidative cleavage to N-Boc quinolyl carboxamides

NMR study on the coordination of dibenzylideneacetone to chiral palladium(0) units. Fluxional behaviour including an intramolecular double bond exchange

Structure and magnetism of the first cyano-bridged hetero-one-dimensional GdIII-CrIII complexes

Studies on aromatic compounds. Part 2. Crystal structure and molecular modeling of 1,3-di-(9-anthracenecarbonyloxy)-2-methylpropane

Synthesis, Characterization, and Magnetic Properties of Self-assembled Compounds Based on Discrete Homotrinuclear Complexes of Cu(II)

Alkynoates as a Source of Reactive Alkylinides for Aldehyde Addition Reactions

Palladium complexes containing bis(oxazolines): stoichiometric versus catalytic allylic alkylation

Nickelacycles with anionic C-N-N' terdentate ligands containing (5,5), (5,6), (5,7) and (6,5) membered fused rings. Reaction with ethylene

Chiral S, S-donor ligands in palladium-catalysed allylic alkylation

Regioncontolled one-step synthesis of 3,3¿-disubtituted 2,2¿-bipyridine ligands by cobalt (i)-catayzed cyclotrimerization

Chorophyl c2 monogalactosyldiacylglyceride ester (ch c2-MGDG). A novel marker pigment for chrysochromulina species (Haptophyta)

Syntesis and molecular structure of the all-trans and the thans.cis.[UOBr2(H2O)2L (L=2,5,8,-trioxanonane; 2,5,8,11,14-pentaoxapentadecane)

N,N'-bis-( 2-tosylaminobenzylidene)-1,3-ethanediamine

Crystallization sovent influence in the crystal structure of Mn( II) and Ni( II) complexes with 2,6-bis( 1- salycilhydrazonoethyl) pyriddine, H4 deps

N,N'-bis-( 2-tosylaminobenzylidene)-1,2-ethanediamine

Algal carotenoids. Part 64. Structura and chemistry of 4-keto-19'-hexanoyloxyfucoxanthin with a novel carotenoid end group

X-Ray analysis of volubilide, a new dedacyclic diels-alder C20-C30 adduct from Hyppocratea volubilis

The main non-polar chlorophyll c from Emiliania huxleyi( Prymnesiophyceae) is a chlorophyll c2-monogalactosyldiacylglyceride ester: A mass spectrometry study

Tris( pyrrolyl)phosphine-substitued acetylene-diCobaltcarbonyl complexes: syntheses, structural characterization and reactivity studies

A new chiral bidentate( P,S) ligand for the asymmetric intermolecular Pauson-Kahnd reaction

Reaction between Hydrazines and chiral a-acetylenic Ketones: synthesis of novel enantiomerically pure Pyrazolyl-b-amino alcohols

Addition compounds of UO2Br2 with O-donor ligands. Molecular structure of cis- and trans-UO2Br2(OAsPh3)2

Reaction between hydrazines and chiral a-acetylenic ketones: synthesis of novel enantiomerically pure pyrazolyl-b-amino alcohols

First Nickel-catalyzed 1,4-conjugate additions to a,b-Unsaturated Systems Using Triorganoindium Compounds

Condensation of 5-aminothienol (2,3-c)pyridazine-6-carboxaldehyde with aliphatic primary amines.Synthesis of New Heterocyclic 2,6,9-Triazabicyclo (3,3,1)nonane Derivatives.