| Department | Biology |
| Knowledgment area | Biochemistry and Molecular Biology |
| Research | Research group Grupo de Investigación en Nanotoxicoloxía e Toxicoloxía Xenética |
| Research lines | Nanotoxicology, Genotoxicity, Citotoxicty, Inmunotoxicology, Environmental Health, Ocupational Health, Biomarkers |
| Contacto | UDC directory |
| Orcid id0000-0001-7537-3977 ResearcherIDH-3039-2018 Scopus56563087900 | |
This section shows the teaching given in degrees, masters and other officers studies in last 6 years.
| Subject and involved studies | Type | Distance hours | Total hours |
|---|---|---|---|
| Biochemistry II | Core | 0 | 30 |
| Biophysics and Biochemistry | Core | 0 | 26 |
| Introduction to Molecular Biology | Optional | 0 | 4 |
| Molecular and Metabolic Biochemistry | Compulsory | 0 | 30 |
Directed or codirected by current teacher since 2013 year.
| Analysis of zinc oxide nanoparticles effects on human glial cell viability |
| Cytotoxicity study of cerium dioxide nanoparticles in human neuronal and glial cells |
Select merit type and year to query research merits.
Evaluación del efecto de la quiralidad en la TOXIcidad de los NANOmateriales (TOXI-NANO)
| Funding entity | CICA - Centro de Investigaciones Científicas Avanzadas |
| Main researches | Blanca Laffon Lage, Jesús Mosquera Mosquera |
| Type | Proyecto Otros Programas |
| Dates | From 01/10/2021 to 30/10/2022 |
Neurotoxicidad de las nanopartículas de óxido de zinc: efectos celulares, moleculares y comportamentales (NeuroiNPact)
| Funding entity | CICA - Centro de Investigaciones Científicas Avanzadas |
| Main researches | Vanessa Valdiglesias García y Mónica Folgueira Otero |
| Type | Proyecto Otros Programas |
| Dates | From 01/10/2021 to 30/10/2022 |
AXUDAS PARA A CONSOLIDACIÓN E ESTRUTURACIÓN DE UNIDADES DE INVESTIGACIÓN COMPETITIVAS. GPC
| Funding entity | CONSELLERÍA DE EDUCACIÓN, UNIVERSIDADE E FORMACIÓN PROFESIONAL |
| Main researches | EDUARDO JOSÉ PÁSARO MÉNDEZ |
| Type | Proyecto Programas Autonomicos |
| Dates | From 01/01/2019 to 20/11/2021 |
Toxicological assessment of silica-coated iron oxide nanoparticles in human astrocytes
| Authors | Fernández-Bertólez, N., Costa, C., Brandao, F., Kiliç, G., Duarte, J.A., Teixeira, J.P., Pásaro, E., Valdiglesias, V., Laffon, B. |
| Journal | FOOD AND CHEMICAL TOXICOLOGY Vol. 118 (pages 13 to 23) |
| DOI | https://doi.org/10.1016/j.fct.2018.04.058 |
Neurotoxicity assessment of oleic acid-coated iron oxide nanoparticles in SH-SY5Y cells
| Authors | Fernández-Bertólez, N., Costa, C., Brandao, F., Kiliç, G., Teixeira, J.P., Pásaro, E., Laffon, B., Valdiglesias, V. |
| Journal | TOXICOLOGY Vol. 406-407 (pages 81 to 91) |
| DOI | https://doi.org/10.1016/j.tox.2018.06.003 |
Comparative study of human neuronal and glial cell sensitivity for in vitro neurogenotoxicity testing
| Authors | Laffon, Blanca, Fernandez-Bertolez, Natalia, Costa, Carla, Pásaro, E., Valdiglesias, Vanessa |
| Journal | FOOD AND CHEMICAL TOXICOLOGY Vol. 102 (pages 120 to 128) |
| DOI | https://doi.org/10.1016/j.fct.2017.02.005 |
In vitro toxicity evaluation of silica-coated iron oxide nanoparticles in human SHSY5Y neuronal cells
| Authors | Kiliç, G., Costa, C., Natalia Fernández-Bertólez, Pásaro, E., Teixeira, J.P., Laffon, B., Valdiglesias, V. |
| Journal | Toxicology Research (pages 235 to 247) |
| DOI | https://doi.org/10.1039/c5tx00206k |
Efectos celulares y moleculares de nanopartículas de magnetita en células neuronales humanas
| Authors | Fernández-Bertólez, N., Gözde Kiliç, Carla Costa, Fátima Brandao, Pásaro, E., Joao Paulo Teixeira, Laffon, B., Valdiglesias, V. |
| Journal | REVISTA DE LA REAL ACADEMIA GALLEGA DE CIENCIAS Vol. XXXV (pages 65 to 104) |
Effects of Iron Oxide Nanoparticles: Cytotoxicity, Genotoxicity, Developmental Toxicity, and Neurotoxicity
| Authors | Valdiglesias, V., Kiliç, G., Costa, C., Natalia Fernández-Bertólez, Pásaro, E., Teixeira, J.P., Laffon, B. |
| Journal | ENVIRONMENTAL AND MOLECULAR MUTAGENESIS Vol. 56 (pages 125 to 148) |
In vitro cytotoxicity of superparamagnetic iron oxide nanoparticles on neuronal and glial cells. Evaluation of nanoparticle interference with viability tests
| Authors | Costa, C., Brandâo, F., Bessa, M.J., Costa, S., Valdiglesias, V., Kiliç, G., Natalia Fernández-Bertólez, Pedro Quaresma, Eulália Pereira, Pásaro, E., Laffon, B., Teixeira, J.P. |
| Journal | JOURNAL OF APPLIED TOXICOLOGY (pages 361 to 372) |
AvaliaÇao in vitro da neurotoxicidade de nanopartículas de magnetite revestidas por sílica
| Authors | Costa, C., Brandâo, F., Kiliç, G., Natalia Fernández-Bertólez, Bessa, M.J., Costa, S., Valdiglesias, V., Laffon, B., Teixeira, J.P. |
| Journal | ObservaÇoes-Boletím Epidemiológico Vol. 4 Num. 2 (pages 42 to 44) |
Cellular and Molecular Toxicity of Iron Oxide Nanoparticles.
| Authors | Laffon, B.. Fernández-Bertólez, N.. Costa, C.. Brandâo, F.. Teixeira, J.P.. Pasaro,E.. Valdiglesias, V. |
| Book |
Cellular and Molecular Toxicology of Nanoparticles Vol. 1048 Publishing: Springer. ISBN: 978-3-319-72040-1 |
| Pages | From 199 to 213 |
The application, neurotoxicity and related mechanism of iron oxide nanoparticles
| Authors | Kiliç, G.. Natalia Fernández-Bertólez. Costa, C.. Brandâo, F.. Joao Paulo Teixeira. Eduarado Pásaro. Laffon, B.. Valdiglesias, V. |
| Book |
Neurotoxicity of Nanomaterials and Nanomedicine Publishing: Elsevier. ISBN: 978-0-12-804598-5 |
| Pages | From 127 to 150 |
Síntese e caracterización de hidrazonas e dos seus complexos de vandio, e estudo das súas posibles aplicacións farmacolóxicas
| Autor | Antía Sar Rañó |
| Director/s | Fernando Francisco Avecilla Porto; Natalia Fernández Bertólez |
| Scope | Facultad de Ciencias |
| Qualification | Sobresaliente Cum Laude |
Toxoplasma IgG serointensity is positively associated with cognitive impairment in older adults even after adjustment for depression
40th International Winter-Workshop on Clinical, Chemical and Biochemical Aspects of Pteridines and Related Topics
International
| Authors | Dagdag, A., Kunwar, J., Mohyuddin, H., Pásaro, E., Constantine, N., Ortmeyer, H., Tizenberg, B., Afram, L., Marano, C., Lowry, C.A., Hoisington, A.J., RachBeisel, J.A., Lema-Arranz, C., Wences-Chirino, T., Fernández-Bertólez, N., Maseda, A., Millán-Calenti, J.C., Kovacs, E.J., Brenner, L.A., Lorenzo-López, L., Valdiglesias, V., Laffon, B., Postolache, T. |
| Organization | International Society of Pteridinology |
| Place | Innsbruck (Austria) |
Analysis of cytotoxicity and genotoxicity of differently charged gold nanoparticles in human SH-SY5Y neuronal cells
51st Meeting of the European Environmental Mutagenesis and Genomics Society (EEMGS 2023)
International
| Authors | Fernández-Bertólez, N., Paz, M., Touzani, A., Baúlde, S., Mosquera J, Criado, A., Pásaro, E., Laffon, B., Valdiglesias, V. |
| Organization | European Environmental Mutagenesis and Genomics Society |
| Place | Málaga (España) |
Influence of surface charge on biological behaviour of gold nanoparticles in human SH-SY5Y neuronal cells
4th International Online Conference on Nanomaterials
International
| Authors | Valdiglesias, V., Paz, M., Touzani, A., Baúlde, S., Mosquera J, Criado, A., Pásaro, E., Méndez, J., Laffon, B., Fernández-Bertólez, N. |
| Place | Online (Otros Organismos Internacionales) |
| DOI | https://doi.org/10.3390/iocn2023-14516 |
Neuron and glial cells exposed to cerium dioxide nanoparticles: results from MTT and yH2AX assays
4th International Online Conference on Nanomaterials
International
| Authors | Fernández-Bertólez, N., Touzani, A., Martínez L., Méndez, J., Reis, A.T., Fraga, S., Teixeira, J.P., Pásaro, E., Laffon, B., Valdiglesias, V. |
| Place | Online (Otros Organismos Internacionales) |
| DOI | https://doi.org/10.3390/iocn2023-14517 |
Cytotoxic effects of zinc oxide nanoparticles on human glial cells
4th International Online Conference on Nanomaterials
International
| Authors | Valdiglesias, V., Touzani, A., Alba-González, A., Folgueira, M., Moreda-Piñeiro, J., Méndez, J., Pásaro, E., Fernández-Bertólez, N., Laffon, B. |
| Place | Online (Otros Organismos Internacionales) |
| DOI | https://doi.org/10.3390/iocn2023-14509 |
Genotoxocity assessment of iron oxide nanoparticles on human astrocytes
Society of Toxicology 57th annual meeting
International
| Authors | Fernández-Bertólez, N., Costa, C., Brandao, F., Fraga, S., Pásaro, E., Laffon, B., Valdiglesias, V., Teixeira, J.P. |
| Place | San Antonio (Texas) (Estados Unidos) |
Genotoxicity evaluation of nanomaterials: What is the most suitable option of in vitro cytokinesis-block micronucleus cytome assay?
56th Annual Meeting Society of Toxicology
International
| Authors | Brandao, F., Costa, C., Valdiglesias, V., Fernández-Bertólez, N., Pásaro, E., Laffon, B., Teixeira, J.P. |
| Place | Baltimore (Maryland) (Estados Unidos) |
Human astrocytes DNA repair competence: influence of iron oxide nanoparticle surface coating
XXIII Reunión Científica de la Sociedad Española de Mutagénesis Ambiental
National
| Authors | Fernández-Bertólez, N., Costa, C., Brandao, F., Fraga, S., Teixeira, J.P., Pásaro, E., Laffon, B., Valdiglesias, V. |
| Place | Oviedo (España) |
Effects of two types of iron oxide nanoparticles on DNA repair competence in human astrocytes
12th International Comet Assay Workshop (ICAW 2017)
International
| Authors | Fernández-Bertólez, N., Costa, C., Brandao, F., Teixeira, J.P., Pásaro, E., Valdiglesias, V., Laffon, B. |
| Place | Pamplona/Iruña (España) |
| DOI | https://doi.org/10.1093/mutage/gex037 |
Toxicity assessment of iron oxide nanoparticles for biomedical applications
2nd International Conference DiMoPEx working groups meeting: Pollution in living and working environments and health
International
| Authors | Fernández-Bertólez, N., Costa, C., Brandao, F., Fraga, S., Teixeira, J.P., Pásaro, E., Laffon, B., Valdiglesias, V. |
| Place | Bentivoglio (Italia) |
| DOI | https://doi.org/10.5696/2156-9614.8.17.1 |
Revisión sistemática de la asociación del estado de fragilidad en la vejez con biomarcadores de estrés oxidativo, daño genómico y reparación celular
59º Congreso de la Sociedad Española de Geriatría y Gerontología - 29º Congreso da Sociedade Galega de Xerontoloxía e Xeriatría
International
| Authors | Joselyn Cortés-Cortés, María Sánchez-Flores, Marcos-Pérez, D., Fernández-Bertólez, N., Ana Maseda, Stefano Bonassi, Vanessa Valdiglesias |
| Organization | Sociedad Española de Geriatría y Gerontología (SEGG) - Sociedade Galega de Xerontoloxía e Xeriatría (SGXX) |
| Place | Coruña, A (España) |
Considering cell type for in vitro neurogenotoxicity testing: Neuronal vs. glial cell sensitivity
Ibero-American Meeting on Toxicology and Environmental Health (IBAMTOX 2016)
International
| Authors | Laffon, B., Fernández-Bertólez, N., J. Méndez, E. Pásaro, Vanessa Valdiglesias 3 |
| Place | Porto (Portugal) |
Analysis of cellular damage induced by silica-coated iron oxide nanoparticles on neuronal cells
3rd International Conference on Occupational & Environmental Toxicology/ 3rd Ibero American Meeting on Toxicology and Environmental Health
International
| Authors | Laffon, B., Kiliç, G., Fernández-Bertólez, N., Costa, C., Costa, S., Teixeira, J.P., Pásaro, E., Valdiglesias, V. |
| Place | Porto (Portugal) |
Genotoxic potential of nanomaterials: in vitro evaluation of iron oxide nanoparticles
44th Annual Meeting European Environmental Mutagenesis and Genomics Society(EEMGS 2015)
International
| Authors | Valdiglesias, V., Fernández-Bertólez, N., Kiliç, G., Costa, C., Costa, S., Teixeira, J.P., Pásaro, E., Laffon, B. |
| Place | Praga (República Checa) |
Micronucleus and H2AX phosphorylation assessment of silica-coated iron oxide nanoparticles in human neuronal cells
44th Annual Meeting European Environmental Mutagenesis and Genomics Society(EEMGS 2015)
International
| Authors | Sánchez-Flores, M., Valdiglesias, V., Kiliç, G., Costa, C., Fernández-Bertólez, N., Costa, S., Teixeira, J.P., Pásaro, E., Laffon, B. |
| Place | Praga (República Checa) |
Comet assay assessment of oleic acid-coated magnetite nanoparticles on human SHSY5Y neuronal cells
11th International Comet Assay Workshop (ICAW 2015)
International
| Authors | Teixeira, J.P., Laffon, B., Kiliç, G., Fernández-Bertólez, N., Costa, C., Costa, S., Pásaro, E., Valdiglesias, V. |
| Place | Amberes (Bélgica) |
| DOI | https://doi.org/10.3389/conf.fgene.2015.01.00026 |
Silica-coated iron oxide nanoparticles do not induce DNA double strand breaks or aneugenicity in SHSY5Y neuronal cells
51st Congress of the European Societies of Toxicology (EUROTOX 2015)
International
| Authors | Sánchez-Flores, M., Kiliç, G., Costa, C., Fernández-Bertólez, N., Costa, S., Teixeira, J.P., Pásaro, E., Valdiglesias, V., Laffon, B. |
| Place | Oporto (Portugal) |
| DOI | https://doi.org/10.1016/j.toxlet.2015.08.593 |
Oxidative stress induced by silica-coated iron oxide nanoparticles in SHSY5Y neuronal cells
51st Congress of the European Societies of Toxicology (EUROTOX 2015)
International
| Authors | Kiliç, G., Costa, C., Fernández-Bertólez, N., Costa, S., Teixeira, J.P., Pásaro, E., Laffon, B., Vdz Park, M., Valdiglesias, V. |
| Place | Oporto (Portugal) |
| DOI | https://doi.org/10.1016/j.toxlet.2015.08.601 |
In vitro toxicity screening of silica-coated superparamagnetic iron oxide nanoparticles in glial cells
51st Congress of the European Societies of Toxicology (EUROTOX 2015)
International
| Authors | Costa, C., Brandao, F., Bessa, M.J., Costa, S., Valdiglesias, V., Kiliç, G., Fernández-Bertólez, N., Pásaro, E., Laffon, B., Teixeira, J.P. |
| Place | Oporto (Portugal) |
| DOI | https://doi.org/10.1016/j.toxlet.2015.08.638 |
Toxic effects of silica coated iron oxide nanoparticles on human neuronal cells
11th Congress of the International Society for Trace Element Research in Humans (ISTERH 2015)
International
| Authors | Kiliç, G., Fernández-Bertólez, N., Costa, C., Costa, S., Teixeira, J.P., Pásaro, E., Laffon, B., Valdiglesias, V. |
| Place | Dubrovnik (Croacia) |
| DOI | https://doi.org/10.1016/j.jtemb.2015.08.001 |
Neuronal DNA damage induced by silica-coated iron oxide nanoparticles
11th International Comet Assay Workshop (ICAW 2015)
International
| Authors | Laffon, B., Kiliç, G., Fernández-Bertólez, N., Costa, C., Costa, S., Teixeira, JP, Pasaro,E., Valdiglesias, V. |
| Place | Amberes (Bélgica) |
Toxicity of silica coated iron oxide nanoparticles on SHSY5Y neuronal cells
6th International Conference on Nanomaterials - Research & Application (NANOCON2014)
International
| Authors | Kiliç, G., Fernández-Bertólez, N., Costa, C., Costa, S., Teixeira, J.P., Pásaro, E., Laffon, B., Valdiglesias, V. |
| Place | Brno (República Checa) |