PhD Juan Antonio Fafián Labora  

Investigador contratado no programa Ramón y Cajal (PR-RC)

Research  Research group Grupo de investigación en Terapia Celular y Medicina Regenerativa
Research lines 1. Role of small extracellular vesicles (sEV) in paracrine senescence and rejuvenation 2. Discovery of new regulators and mechanism in senescence-associated secretory phenotype (SASP) in cellular senescence, ageing and progeria 3. Ferroptosis as a new target metabolic process for the treatment of age-related diseases and cancer
Keywords small extracellular vesicles (sEV), ageing, cellular senescence, senescence-associated secretory phenotype (SASP), progeria (HGPS), ferroptosis, epithelial ovarian cancer
Contacto UDC directory
Orcid id0000-0003-1510-8666 ResearcherIDAAB-4877-2019 Scopus56703476000

Teaching

Subjects taught

This section shows the teaching given in degrees, masters and other officers studies in last 6 years.

Subject and involved studies Distance hours Total hours
Anatomy of the Organs of Hearing and Speech
Degree in Speech Therapy
0 15
Cell Culture Techniques
Master's Degree in Health Care and Research
0 4
Cellular and Tissue Engineering
Master's in Advanced Biotechnology
0 7
Histological Techniques
Master's Degree in Health Care and Research
0 5
Nanotechnology in Medicine
Degree in Nanoscience and Nanotechnology
0 19
Protein Analysis and Handling Techniques
Master's Degree in Health Care and Research
0 3
Stem Cells and Cell Therapy
Master's in Molecular Cellular and Genetic Biology
0 9
Subject and involved studies Distance hours Total hours
Anatomy of the Organs of Hearing and Speech 0 15
Cell Culture Techniques 0 12
Cellular and Tissue Engineering 0 7
Histological Techniques 0 12
Master`s Dissertation: Fundamentals of Biomedical Research 0 4
Master's Dissertation 0 4
Master's Dissertation 0 4
Nanotechnology in Medicine 0 19
Protein Analysis and Handling Techniques 0 8
Stem Cells and Cell Therapy 0 5.5
Subject and involved studies Distance hours Total hours
Anatomy of the Organs of Hearing and Speech
Degree in Speech Therapy
0 15
Cell Culture Techniques
Master's Degree in Health Care and Research
0 12
Cellular and Tissue Engineering
Master's in Advanced Biotechnology
0 7
Histological Techniques
Master's Degree in Health Care and Research
0 12
Master's Dissertation
Master's in Molecular Cellular and Genetic Biology
0 0
Master's Dissertation
Master's in Advanced Biotechnology
0 0
Protein Analysis and Handling Techniques
Master's Degree in Health Care and Research
0 8
Stem Cells and Cell Therapy
Master's in Molecular Cellular and Genetic Biology
0 5.5
Subject and involved studies Distance hours Total hours
Cell Culture Techniques
Master`s Degree in Health Care and Research
Master's Degree in Health Care and Research (Optional)
0 12
Cellular and Tissue Engineering
Master's in Advanced Biotechnology
0 7.5
Histological Techniques
Master`s Degree in Health Care and Research
Master's Degree in Health Care and Research (Optional)
0 12
Master's Dissertation
Master's in Molecular Cellular and Genetic Biology
0 4
Protein Analysis and Handling Techniques
Master`s Degree in Health Care and Research
Master's Degree in Health Care and Research (Optional)
0 4
Stem Cells and Cell Therapy
Master's in Molecular Cellular and Genetic Biology
0 5.5
Subject and involved studies Distance hours Total hours
Cell Culture Techniques
Master`s Degree in Health Care and Research
0 11
Handling and Analysis Techniques for Proteins
Master`s Degree in Health Care and Research
0 12.5
Histological Techniques
Master`s Degree in Health Care and Research
0 9
Subject and involved studies Distance hours Total hours
Cell Culture Techniques
Master`s Degree in Health Care and Research
0 9
Handling and Analysis Techniques for Proteins
Master`s Degree in Health Care and Research
0 11
Histological Techniques
Master`s Degree in Health Care and Research
0 11
Scientific Seminars
Master`s Degree in Health Care and Research
0 3
Work Placement in a Research Group
Master`s Degree in Health Care and Research
0 4

EOG works and final master thesis directed

Directed or codirected by current teacher since 2013 year.

Development of new non-viral systems for genetic modification in senescent cells
Ferroptosis: new therapeutic approach for epithelial ovarian cancer
Non-viral systems based on niosomes as new tools for senescent cells gene transfer
Study of new regulators in inflamm-aging
Effect of miR-21 over-expression on immunology profile of mesenchymal stem cells
New non-viral system development for genetic modification of mesenchymal stem cells
Role of p65/RelA in cellular senescence and inflamation

Research results

Select merit type and year to query research merits.

CONTRATO RAMÒN Y CAJAL

Funding entity Ministerio de Economía y Competitividad (MINECO)
Type Contrato
Dates From 01/01/2023 to 31/01/2028

AYUDA INTALENT-UDC

Funding entity INDITEX-UDC INTALENT PROGRAMA
Type Proyecto Programas Autonomicos
Dates From 01/01/2023 to 01/01/2025

AYUDAS PARA LA CONSOLIDACIÓN Y ESTRUTURACIÓN DE UNIDADES DE INVESTIGACIÓN COMPETITIVAS. GPC 2023

Funding entity Consellería de Cultura, Educación e Ordenación Universitaria
Main researches Silvia María Díaz Prado
Type Proyecto Programas Autonomicos
Dates From 01/01/2023 to 20/11/2025

AXUDAS PARA A CONSOLIDACIÓN E ESTRUTURACIÓN DE UNIDADES DE INVESTIGACIÓN COMPETITIVAS.EXCELENCIA 2023

Funding entity CONSELLERIA DE EDUCACIÓN, UNIVERSIDADE E FORMACIÓN PROFESIONAL
Main researches Juan Antonio Fafián Labora
Type Proyecto Programas Autonomicos
Dates From 01/01/2023 to 20/11/2027

Discovery new therapeutic pathways involved in the paracrine ferrotosis mediated by small extraclelular vesicles in epithelial ovarian cancer

Funding entity Universidade da Coruña (UDC)
Type Proyecto Otros Programas
Dates From 01/11/2021 to 31/10/2022

Plasmalogens, exosomes and autophagy in aging and neurodegeneration

Funding entity Ministerio de Economía y Competitividad (MINECO)
Main researches JOSE ANTONIO RODRÍGUEZ NAVARRO
Type Proyecto Programas Nacionales
Dates From 01/01/2021 to 31/01/2024

AXUDAS A COMPLETAR A ETAPA POSTDOCTORAL POR LA XUNTA DE GALICIA

Funding entity Xunta de Galicia
Type Contrato
Dates From 01/04/2021 to 31/12/2022

Determination of the senescence associated secretory phenotype (SASP) regulated by the extracellular vesicles biogenesis pathway Rab27a

Funding entity ProteoRed ISCIII
Type Proyecto Programas Nacionales
Dates From 30/06/2020 to 30/06/2021

Axudas para a consolidación e estruturación de unidades de investigación competitivas-GPC

Funding entity Consellería de Educación e Ordenación Universitaria
Main researches Díaz Pardo, Silvia
Type Proyecto Programas Autonomicos
Dates From 01/01/2020 to 31/12/2023

Terapia celular con microRNA y vesículas extracelulares para el tratamiento de la inflamación crónica en un modelo OA (Terapia libre de células)

Funding entity Ministerio de Ciencia, Innovación y Universidades
Type Proyecto Programas Nacionales
Dates From 30/07/2020 to 30/07/2023

ZEBRAGING DE LAS Ayudas para proyectos Semilla colaborativos entre grupos de la AE CICA-INIBIC

Funding entity CICA - Centro de Investigaciones Científicas Avanzadas
Main researches MARIA ARUFE
Type Proyecto Programas Autonomicos
Dates From 22/11/2019 to 22/11/2020

Study of antioxidant potential of small extracellular vesicles

Funding entity BARTS CHARITY
Type Proyecto Internacional
Dates From 01/12/2019 to 01/12/2020

Contrato Posdoctoral por la Xunta de Galicia Modalidad A (Juan Antonio Fafián Labora)

Funding entity Consellería de Cultura, Educación e Ordenación Universitaria
Main researches Juan Antonio Fafián Labora
Type Contrato
Dates From 30/06/2017 to 31/12/2020

Study of Ferroptosis Transmission by Small Extracellular Vesicles in Epithelial Ovarian Cancer Cells

Authors Carmen Alarcón-Veleiro, Rocío Mato-Basalo, Sergio Lucio-Gallego, Andrea Vidal-Pampín, María Quindós-Varela, T. Al-Qatarneh, Germán Berrecoso, Ángel Vizoso-Vázquez, M. Arufe, Fafián-Labora J
Journal ANTIOXIDANTS Vol. 12 (pages 183 to 183)
DOI https://doi.org/10.3390/antiox12010183

Development of new non-viral systems for genetic modification of senescent cells

Authors López-Seijas, Junquera, Miranda-Balbuena, Diego, Iglesias-Fente, Alba, Sacristán-Santos, Marta, Carballo-Pedrares, Natalia, M. Arufe, Rey-Rico, A, Fafián-Labora J
Journal MOLECULAR THERAPY-NUCLEIC ACIDS
DOI https://doi.org/10.1016/j.omtn.2023.03.010

Therapy free of cells vs human mesenchymal stem cells from umbilical cord stroma to treat the inflammation in OA.

Authors Rocío Mato-Basalo, Sergio Lucio-Gallego, Lucía Silva-Fernández, Alba González-Rodríguez, Fco. Javier de Toro, Juan Antonio Fafián Labora, María C Arufe
Journal CELLULAR AND MOLECULAR LIFE SCIENCES
DOI https://doi.org/10.1007/s00018-022-04580-z

Genome wide CRISPR/Cas9 screen identifies the coagulation factor IX (F9) as a regulator of senescence

Authors Carpintero-Fernández Paula, Borghesan Michela, Eleftheriadou Olga, Fafián-Labora Juan, Mitchell Tom P, Yuste Alejandro, Ogrunc Mugue, Nightingale Thomas D, Mayán MD, OLoghlen Ana
Journal Cell Death & Disease
DOI https://doi.org/10.1038/s41419-022-04569-3

Therapeutic potential for regulation of the nuclear factor kappa-B Transcription Factor p65 to prevent cellular senescence and activation of pro-inflammatory in mesenchymal stem cells

Authors Rocío Mato-Basalo, M Morente-López, Onno J. Arntz, Fons A. J. van de Loo, Fafián-Labora J, M.C. Arufe
Journal International Journal of Molecular Sciences
DOI https://doi.org/10.3390/ijms22073367

High-Throughput Screen Detects Calcium Signaling Dysfunction in Hutchinson-Gilford Progeria Syndrome

Authors Juan A Fafián-Labora, Miriam Morente-López, Fco Javier de Toro, María C Arufe
Journal International Journal of Molecular Sciences Vol. 22 Num. 14
DOI https://doi.org/10.3390/ijms22147327

Mesenchymal Stem Cell-Derived Extracellular Vesicle Isolation and Their Protein Cargo Characterization

Authors Morente-López M, Fafián-Labora J, Carrera M, de Toro FJ, Gil C, Mateos J, M. Arufe
Journal Methods Mol Biol Vol. 2259 (pages 3 to 12)
DOI https://doi.org/10.1007/978-1-0716-1178-4_1

NF-¿B/IKK activation by small extracellular vesicles within the SASP

Authors Fafián-Labora Juan, OLoghlen Ana
Journal Aging Cell
DOI https://doi.org/10.1111/acel.13426

Influence of mesenchymal stem cell-derived extracellular vesicles in vitro and their role in ageing

Authors Juan Fafián-Labora, M. Morente-López, MJ Sánchez-Dopico, O. J. Arntz, F. A. J. van de Loo, de Toro FJ, M. Arufe
Journal Stem Cell Research & Therapy Vol. 11 Num. 3
DOI https://doi.org/10.1186/s13287-019-1534-0.

Small Extracellular Vesicles Have GST Activity and Ameliorate Senescence-Related Tissue Damage

Authors Fafián-Labora J, Rodríguez-Navarro JA
Journal CELL METABOLISM (pages 71 to 86)
DOI https://doi.org/10.1016/j.cmet.2020.06.004

Small Extracellular Vesicles Are Key Regulators of Non-cell Autonomous Intercellular Communication in Senescence via the Interferon Protein IFITM3.

Authors Juan Fafián-Labora
Journal Cell Reports
DOI https://doi.org/10.1016/j.celrep.2019.05.095

FASN activity is important for the initial stages of the induction of senescence

Authors Juan Fafián-Labora, Paula Carpintero-Fernández, Samuel JD Jordan, Tamanna Shikh-Bahae, Sana Mohammad Abdullah, Midusa Mahenthiran, José Antonio Rodríguez-Navarro, Maria Victoria Niklison-Chirou
Journal Cell Death & Disease
DOI https://doi.org/10.1038/s41419-019-1550-0

Next-Generation Sequencing and Quantitative Proteomics of Hutchinson-Gilford progeria syndrome-derived cells point to a role of nucleotide metabolism in premature aging

Authors Mateos J, Juan Fafián-Labora, Morente-López M, Lesende-Rodríguez IA, L. Monserrat, Ódena MA, E. de Oliveira, de Toro FJ, MC Arufe
Journal PLOS ONE
DOI https://doi.org/10.1371/journal.pone.0205878

Effect of age on pro-inflammatory miRNAs contained in mesenchymal stem cells-derivaded extracellular vesicles

Authors J Fafián-Labora, I. Rodríguez-Lesende, P. Fernández-Pernas, S. Sangiao-Alvarellos, L. Monserrat, O. Arntz, F. Vand de Loo, J Mateos, M.C. Arufe
Journal SCIENTIFIC REPORTS Vol. 7
DOI https://doi.org/10.1038/srep43923.

BIODISTRIBUTION AND IMMUNOGENICITY OF ALLOGENEIC MESENCHYMAL STEM CELLS IN A RAT MODEL OF INTRAARTICULAR CHONDROCYTE XENOTRANSPLANTATION

Authors Maribel Marquina, Javier A. Collado, Magdiel Pérez-Cruz, Pablo Fernández-Pernas, Juan Fafián-Labora, Fco. Blanco, Rafael Mañez, María C. Arufe, Cristina Costa
Journal FRONTIERS IN IMMUNOLOGY
DOI https://doi.org/10.3389/fimmu.2017.01465

Technical Advances to Study Extracellular Vesicles.

Authors Fafián-Labora J, Carpintero-Fernández P
Journal Frontiers in Cell and Developmental Biology

3, 3',5-Triiodo-L-Thyronine Increases In Vitro Chondrogenesis of Mesenchymal Stem Cells from Human Umbilical Cord Stroma Through SRC2

Authors P Fernández-Pernas, J Fafián-Labora, I. Lesende-Rodriguez, J. Mateos, A de la Fuente, I. Fuentes, F.J. De Toro Santos, Fco. Blanco, MC Arufe
Journal Journal of Cellular Biochemistry Vol. 117 Num. 9 (pages 2097 to 2108)
DOI https://doi.org/10.1002/jcb.25515

iTRAQ-based analysis of progerin expression reveals mitochondrial dysfunction, reactive oxygen species accumulation and altered proteostasis

Authors J Mateos, A. Landeira-Abia, JA Fafián-Labora, P Fernández-Pernas, I Lesende-Rodríguez, P Fernández-Puente, M Fernández-Moreno, A Delmiro, MA Martín, Fco Blanco, MC Arufe
Journal Stem Cell Research & Therapy Vol. 6 Num. 1
DOI https://doi.org/10.1186/s13287-015-0110-5

Influence of age on rat bone marrow mesenchymal stem cells potential

Authors J Fafián-Labora, P. Fernández-Pernas, I. Fuentes, N Oreiro, Fco. J. De Toro, S. Sangiao-Alvarellos, J. Mateos, MC Arufe
Journal SCIENTIFIC REPORTS
DOI https://doi.org/10.1038/srep16765

Development of new non-viral systems for genetic modification of senescent cells
Cellular Aging and Metabolism Symposium (CAMS) 2022
International

Authors Miranda- Balbuena, D, López-Seijas, J, Sacristan-Santos, M, Carballo-Pedrares, N, MC Arufe, Rey-Rico, A, Fafián-Labora J
Place Coruña, A (España)

Development of new non-viral systems for genetic modification of senescent cells
European Society of Gene and Cell Therapy (ESGCT) & British Society of Gene and Cell Therapy (BSGCT)
International

Authors Miranda-Balbuena, D, Lopez-Seijas, J, Sacristan-Santos, M, Carballo-Pedrares, N, MC Arufe, Fafián-Labora J, Rey-Rico, A
Place Edimburgo (Reino Unido)

Production of knockout models in two established cell line for the study of ferroptosis in ovarian cancer
44º SEBBM
National

Authors T. Al-Qatarneh, Cora Rey-Souto, Rocío Mato-Basalo, M. Arufe, Juan Fafián-Labora, Ángel Vizoso-Vázquez
Place Málaga (España)

Study of ferroptosis transmission by small extracellular vesicles in epithelial ovarian cancer cells
18th ASEICA INTERNATIONAL CONGRESS
International

Authors Alarcón-Veleiro C, Mato-Basalo Rocío, Lucio-Gallego Sergio, Vidal-Pampín Andrea, Quindos-Varela María, Al-Qatarneh Thamer, Vizoso-Vázquez Ángel, M. Arufe, Fafián-Labora Juan
Place Santiago de Compostela (España)

Role of miR-21 in Therapy free of cells vs mesenchymal stem cells to treat the inflammation in OA model
Cellular Aging and Metabolism Symposium (CAMS) 2022
International

Authors Morente-López Miriam, Mato-Basalo Rocío, Lucio-Gallego Sergio, Silva Lucía, García Sánchez Alba, De Toro Francisco Javier, Fafián-Labora Juan, M. Arufe
Place Coruña, A (España)

STUDY OF FERROPTOSIS TRANSMISSION BY SMALL EXTRACELLULAR VESICLES IN EPITHELIAL OVARIAN CANCER CELLS
CIMUS SYMPOSIUM 1ST EDITION
Autonomous

Authors Alarcón-Veleiro Carmen, Mato-Basalo Rocío, Lucio-Gallego Sergio, Quindos-Varela María, Al-Qatarneh Thamer, Ángel Vizoso-Vázquez, M. Arufe, Fafián-Labora Juan
Place Santiago de Compostela (España)

Senescence based on the purine metabolism, new target to treat age-related diseases
CIMUS SYMPOSIUM 1ST EDITION
Autonomous

Authors Mato-Basalo Rocío, Lucio-Gallego Sergio, Alarcón-Veleiro Carmen, Fafián-Labora Juan, M. Arufe
Place Santiago de Compostela (España)

New regulators of senescence-associated secretory phenotype mediated by small extracellular vesicles as senomorphics targets to treat age-related disease
CIMUS SYMPOSIUM 1ST EDITION
Autonomous

Authors Lucio-Gallego Sergio, Mato-Basalo Rocío, Alarcón-Veleiro Carmen, Carrera Mónica, Gil Concha, Mateos Jesús, M. Arufe, Fafián-Labora Juan
Place Santiago de Compostela (España)

Undiscovered of regulators of senescence-associated secretory phenotype mediated by small extracellular vesicles
MOLECULAR, CELLULAR AND ORGANISMAL DRIVERS OF AGING
International

Authors Lucio-Gallego Sergio, Mato-Basalo Rocío, Alarcón-Veleiro Carmen, Carrera Mónica, Gutiérrez Lola, Gil Concha, Mateos Jesús, M. Arufe, Fafián-Labora Juan
Place Madrid (España)

Therapy free of cells vs human mesenchymal stem cells from umbilical cord stroma to treat the inflammation in OA
European Society of Gene and Cell Therapy (ESGCT) & British Society of Gene and Cell Therapy (BSGCT)
International

Authors Morente-López Miriam, Mato-Basalo Rocío, Lucio-Gallego Sergio, Silva Lucía, García-Sánchez Alba, de Toro FJ, Fafián-Labora Juan, M. Arufe
Place Edimburgo (Reino Unido)

Effect of miR-21 into mesenchymal stem cells -derived extracellular vesicles behaviour on inflamm-aging
6th GEIVEX SYMPOSIUM
National

Authors Morente-López M, Mato-Basalo Rocío, Carrera Mónica, Gil Concha, Mateos Jesús, Fafián-Labora Juan, M. Arufe
Place Santiago de Compostela (España)

Effect of miR-21 into mesenchymal stem cells -derived extracellular vesicles behaviour on inflammaging
6th GEIVEX SYMPOSIUM
National

Authors Morente-López Miriam, Mato-Basalo Rocío, Gil Concha, Carrera Mónica, Fafián-Labora Juan, Mateos Jesús, M. Arufe
Place Santiago de Compostela (España)

Ferroptosis transmission by small extracellular vesicles in epithelial ovarian cancer cells
6th GEIVEX SYMPOSIUM
National

Authors Alarcón-Veleiro Carmen, Mato-Basalo Rocío, Lucio-Gallego Sergio, Quindos-Varela María, Al-Qatarneh Thamer, Vizoso-Vázquez Ángel, M. Arufe, Fafián-Labora Juan
Place Santiago de Compostela (España)

STUDY OF FERROPTOSISTRANSMISSION BY SMALL EXTRACELLULARVESICLES IN EPITHELIAL OVARIAN CANCERCELLS
VIII EDITION BIOMEDICAL CANCER RESEARCH CONFERENCE
Autonomous

Authors Alarcón-Veleiro Carmen, Mato-Basalo Rocío, Lucio-Gallego Sergio, Quindos-Varela María, Al-Qatarneh Thamer, Vizoso-Vázquez Ángel, M. Arufe, Fafián-Labora Juan
Place Coruña, A (España)

Roleof miR-21 onMSC-derived EV and their paracrine effect
ISEV 2022
International

Authors Morente-López Miriam, Mato-Basalo Rocío, Miranda Quintana María del Pilar, Lucio-Gallego Sergio, Fafián-Labora Juan, M. Arufe
Place Lyon (Francia)

Development of senomorphics based on intercellular communication through sEV to rejuvenate senescent mesenchymal stem cells
ISEV 2022
International

Authors Mato-Basalo Rocío, Lucio-Gallego Sergio, Sacristán-Santos Marta, Miranda Quintana María del Pilar, Morente-López Miriam, M. Arufe, Fafián-Labora Juan
Place Lyon (Francia)

Undiscovery of regulators of senescence-associated secretory phenotype mediated by small extracellular vesicles
PROTEO VILAMOURA 2022
International

Authors Fafián-Labora Juan
Place Vilamoura (Portugal)

Study of ferroptosis transmission by small extracellular vesicles in epithelial ovarian cancer cells
SEBBM 2022
National

Authors Alarcón-Veleiro Carmen, Mato-Basalo Rocío, Lucio-Gallego Sergio, Quindos-Varela María, Al-Qatarneh Thamer, Vizoso-Vázquez Ángel, M. Arufe, Fafián-Labora Juan
Place Málaga (España)

Senescence based on the purine metabolism, new target to treat age-related diseases
SEBBM 2022
National

Authors Mato-Basalo Rocío, Lucio-Gallego Sergio, Alarcón-Veleiro Carmen, M. Arufe, Fafián-Labora Juan
Place Málaga (España)

Effect of miR-21 into mesenchymal stem cells - derived extracellular vesicles on inflamm-aging
SEBBM 2022
National

Authors Morente-López Miriam, Mato-Basalo Rocío, Gil Concha, Carrera Mónica, Fafián-Labora Juan, Mateos Jesús, M. Arufe
Place Málaga (España)

New regulators of senescence-associated secretory phenotype mediated by small extracellular vesicles as senomorphic targets to treat age-related disease
SEBBM 2022
National

Authors Lucio-Gallego Sergio, Mato-Basalo Rocío, Alarcón-Veleiro Carmen, Carrera Mónica, Gutiérrez Lola, Gil Concha, Mateos Jesús, M. Arufe, Fafián-Labora Juan
Place Málaga (España)

Study of ferroptosis transmission by small extracellular vesicles in epithelial ovarian cancer cells
SETGYC 11th BIENNIAL CONGRESS
National

Authors Alarcón-Veleiro Carmen, Mato-Basalo Rocío, Lucio-Gallego Sergio, Quindos-Varela María, Al-Qatarneh Thamer, Vizoso-Vázquez Ángel, M. Arufe, Fafián-Labora Juan
Place Sevilla (España)

Therapy free of cells vs human mesenchymal stem cells from umbilical cord stroma to treat the inflammation in OA
SETGYC 11th BIENNIAL CONGRESS
National

Authors Morente-López Miriam, Mato-Basalo Rocío, Lucio-Gallego Sergio, Silva Lucía, García Sánchez Alba, de Toro FJ, Fafián-Labora Juan, M. Arufe
Place Sevilla (España)

ROLE OF SMALL EXTRACELLULAR VESICLES IN AGEING AND CELLULAR SENESCENCE
UKEV FORUM 2020
International

Authors Fafián-Labora Juan
Place LONDRÉS (Reino Unido)

EL PAPEL DE LAS VESÍCULAS EXTRACELULARES EN ENVEJECIMIENTO Y REJUVENECIMIENTO
AGING AND AGE-RELATED DISEASES: FROM MECHANISMS TO ADVANCED THERAPIES
Autonomous

Authors Fafián-Labora Juan
Place Coruña, A (España)

Development of senomorphics based on intercellular communication to treat agerelated disease
GEIVEX/TeNTaCLES 2021 MINISYMPOSIUM
National

Authors Fafián-Labora Juan, Mato-Basalo Rocío, Lucio-Gallego Sergio, Sacristán-Santos Marta, Miranda Quintana María del Pilar, López-Morente Miriam, M. Arufe
Place Madrid (España)

Development of senomorphics based on intercellular communication to treat age-related disease
6th International Cell Senescence Association (ICSA) Conference
International

Authors Mato-Basalo Rocío, Lucio-Gallego Sergio, Sacristán-Santos Marta, Miranda-Quintana María del Pilar, Morente-López Miriam, M. Arufe, Fafián-Labora Juan
Place Osaka (Japón)

Role of Purine metabolism in cellular senescence and ageing
SEBBM 2021
National

Authors Fafián-Labora Juan, Mato-Basalo Rocío, Miranda Quintana María del Pilar, Sacristán-Santos Marta, VAN DE LOO FONS, ARNTZ ONNO, M. Arufe
Place Barcelona (España)

Role of small extracellular vesicles in ageing and cellularsenescence
YOUNG ICSA SEMINAR 2021
International

Authors Fafián-Labora Juan
Place Londrés (Reino Unido)

Proteomic study of mesenchymal stem cells derived esoxomes modified using miR.
Annual Meeting ISEV 2020
International

Authors Miriam Morente-López, Juan A. Fafián-Labora, Jesús Mateos, Mónica Carrera, María Arufe
Organization International Society for Extracellular Vesicles
Place Coruña, A (España)

Purine-metabolism: new regulator of senescence associated secretory phenotype mediated by exosome-like particles
MINISIMPOSIUM GEIVEX-TENTACLES-UFV 2020
National

Authors Juan Fafián-Labora, Mato Basalo R, Miriam Morente-López, Arntz O, Van de Loo FJ, María C Arufe
Organization GEIVEX
Place Madrid (España)

Proteomic study of mesenchymal stem cells derived exosomes
PROTEOVIEDO 2020
Autonomous

Authors Morente-López Miriam, Fafián-Labora Juan, Mateos Jesús, Gutiérrez Lola, HERMÁEZ LUISA, Gil Concha, Carrera Mónica, M. Arufe
Place Oviedo (España)

¿Small extracellular vesicles in cellular senescence and ageing¿
GENOMICS AND CHILD HEALTH VIRTUAL RESEARCH SEMINAR
International

Authors Fafián-Labora Juan
Place Londrés (Reino Unido)

El papel de las vesículas extracelulares en envejecimiento celular
HAPPY HOUR CICA-INIBIC 2020
Autonomous

Authors Fafián-Labora Juan
Place Coruña, A (España)

Novel regulators of senescence: in disease and health
International Cellular Senescence Association Conference 2019
International

Authors Fafián-Labora J
Place Atenas (Grecia)

TERAPIA CELULAR CON MICRO-ARN E EXOSOMAS PARA O TRATAMENTO DA INFLAMACIÓN CRÓNICA NUN MODELO DE ARTROSE
BIOINTEGRASAÙDE 2019
Autonomous

Authors Morente-López Miriam, Fafián-Labora Juan, M. Arufe
Place Santiago de Compostela (España)

Small Extracellular Vesicles in senescence and ageing
EXTRACELLULAR VESICLES SYMPOSIUM
International

Authors Fafián-Labora Juan
Place Londrés (Reino Unido)

Role of small extracellular vesicles in ageing
ISEV 2019
International

Authors Fafián-Labora Juan, OLoghlen Ana, Carpintero-Fernández Paula, Eleftheriadou Olga
Place KYOTO (Japón)

Interferon protein 3 mediates paracrine senescence in human primary fibroblasts
SEBC 2019
National

Authors OLoghlen Ana, Fafián-Labora Juan, Borghesan Michela, Eleftheriadou Olga, Carpintero-Fernández Paula
Place Badajoz (España)

SMALL EXTRACELLULAR VESICLES ARE JEY REGULATORS OF NON-CELL AUTONOMOUS INTERCELLULAR COMMUNICATION IN SENESCENT VIA THE INTERFERON PROTEIN, IFITM3
SEMINARIO HOSPITAL RAMÓN Y CAJAL IRYCIS
National

Authors Fafián-Labora Juan
Place Madrid (España)

Functionality of bone marrow mesenchymal stem cell-derived extracellular vesicles on self-renewal
Annual Meeting International Society for Extracelular vesicles ISEV2018
International

Authors Juan Fafián-Labora, M. MOrente-López, P. Diaz-Barreiro, p. Fernández-Pernas, M.C.Arufe
Place Barcelona (España)
DOI https://doi.org/10.1080/20013078.2018.1461450

Quantitative proteomics and whole transcriptomics sequencing of Progeria- derived cells point to a key role of nucleotide metabolism in premature aging
EUPA 2018
International

Authors Jesús Mateos, Miriam Morente-López, Juan Fafián Labora, Iván Lesende-Rodríguez, María A. Òdena, Eliandre De Oliveira, Lorenzo Monserrat, Javier De Toro, MC Arufe
Organization Sociedad Española de Proteómica
Place Santiago de Compostela (España)

The bystander effect of exosomes in ageing
ISEV 2018
International

Authors Borghesan Michela, Fafián-Labora Juan, Carpintero-Fernández Paula, OLoghlen Ana
Place Barcelona (España)

FASN activity is important for the initial stages of senescence induction in cells
IX REUNIÓN DE JÓVENES INVESTIGADORES EN EL EXTRANJERO 2018
International

Authors Fafián-Labora Juan
Place Coruña, A (España)

ROLE OF SMALL EXTRACELLULAR VESICLES IN AGEING
I JORNADA DE VESÍCULAS EXTRACELULARES
Autonomous

Authors Fafián-Labora Juan
Place Coruña, A (España)

ROLE OF FASN IN CELLULAR SENESCENCE
2018 William Harvey Day
International

Authors Fafián-Labora Juan
Place Londrés (Reino Unido)

Effect of ageing on pro-inflammatory micro-RNAs contained in MSC-derived extracellular vesicles
ISEV 2016
International

Authors J Fafián-Labora, P. Fernández-Pernas, Onno J. Arntz, Miranda Bennink, Fons A.J Van de Loo, María C. Arufe
Organization International Society for Extracellular Vesicles
Place Rotterdam (Países Bajos)

Quantitative Proteomics and Whole Transcriptomics Sequencing of Progeria-derived Cells Point to a Key Role of IGF Signaling Pathway in Premature Aging
15th Human Proteome Organization Congress
International

Authors J Fafián-Labora, I. Lesende-Rodriguez, L. Monserrat, A. Odena, E. de Oliveira, MC Arufe, J. Mateos
Organization HUPO
Place Taipei (Taiwán)

Proteome and Transcriptome analysis in rat bone marrow mesenchymal stem cells at different ages
6th Congress of Spanish Proteomics Society
National

Authors JA Fafian-Labora, Iván Lesende Rodríguez, P. Fernández Pernas, S Sangiao-Alvarellos, L Monserrat, Mateos J, MC Arufe
Organization Sociedad Española de Proteómica
Place Cádiz (España)

EFFECT OF AGEING ON PRO-INFLAMMATORY MICRO-RNAS CONTAINED IN MSC-DERIVED EXTRACELLULAR VESICLES
SEMINARIO INIBIC 2016
Autonomous

Authors Fafián-Labora Juan
Place Coruña, A (España)

Estudio del efecto del envejecimiento sobre el proteoma de las células madre mesenquimales mediante iTRAQ
IV Jornadas Bienales de Jóvenes Investigadores en Proteómica
National

Authors J Fafián-Labora, J Mateos, P Fernández, S Sangiao, MC Arufe
Organization Sociedad Española de Proteómica (SEProt)
Place Bilbao (España)

Role of ageing in mesenchymal stem cells behaviour
World Conference on Regenerative Medicine 2015
International

Authors J Fafián-Labora, P. Fernández-Pernas, J. Mateos, S. Sangiao-Alvarellos, MC Arufe
Organization Fraunhofer Institute for cell therapy and immunology
Place Leipzig (Alemania)

Protemic analyis of proteome from mesenchymal stem cells at several ages
Late Summer Austrian Proteomics Seminar 2015
International

Authors Fafián-Labora Juan
Place Viena (Austria)

Estudio del efecto del envejecimiento sobre el proteoma de las células madre mesenquimales mediante iTRAQ
XII BIOINTEGRASAÙDE 2015
Autonomous

Authors Fafián-Labora Juan, Mateos, Jesús, Fernández-Pernas, Pablo, Susana Sangiao Alvarellos, M. Arufe
Place Vigo (España)

Influencia del envejecimiento en el perfil pro-inflamatorio de micro-RNAs contenidos en los exosomas procedentes de células madre mesenquimales
VI REUNIÓN JÓVENES INVESTIGADORES EN EL EXTRANJERO
International

Authors Fafián-Labora Juan
Place Coruña, A (España)

PROTEOMIC STUDY OF MESENCHYMAL STEM CELLS DURING AGEING BY iTRAQ
XXXV REUNIÓN BIENAL RSEQ 2015
Autonomous

Authors Fafián-Labora Juan
Place Coruña, A (España)

the age-related differences in the microRNA content of the extracellular vesicles and these consequences for their therapeutic potential
Seminar Radboud University medical center in Nijmegen
International

Authors Fafián-Labora Juan
Place Nijmegen (Países Bajos)

Quantitative proteomic analysis of rat mesenchymal stem cells at different ages
13th Human Proteome Organization World Congress (HUPO).
International

Authors Juan Fafián, J. Mateos, P. Fernández, S. Sangiao-Alvarellos, I Fuentes, J de Toro, F.J. Blanco, MC Arufe
Organization HUPO
Place Madrid (España)

Study of the long term stability of an industrial polyamide from a contemporary artwork
The International Congress on Science and Technology for the Conservation of Culture
International

Authors Juan Fafián-Labora, Thais López-Morán, Arturo López-Quintela, M Lazzari
Place Santiago de Compostela (España)

Positions

Academic or management positions held by teacher.

Consello do Departamento Fisioterapia, Medicina e Ciencias Biomédicas

PDI (Membros Natos)

From 16/03/2023.

Consello do Departamento Fisioterapia, Medicina e Ciencias Biomédicas

PDI (Membros Natos)