CONTRATO RAMÒN Y CAJAL
| Funding entity | Ministerio de Economía y Competitividad (MINECO) |
| Type | Contrato |
| Dates | From 01/01/2023 to 31/01/2028 |
| Research | Research group Grupo de investigación en Terapia Celular y Medicina Regenerativa |
| Research lines | 1. Role of small extracellular vesicles (sEV) in paracrine senescence and rejuvenation 2. Discovery of new regulators and mechanism in senescence-associated secretory phenotype (SASP) in cellular senescence, ageing and progeria 3. Ferroptosis as a new target metabolic process for the treatment of age-related diseases and cancer |
| Keywords | small extracellular vesicles (sEV), ageing, cellular senescence, senescence-associated secretory phenotype (SASP), progeria (HGPS), ferroptosis, epithelial ovarian cancer |
| Contacto | UDC directory |
| Orcid id0000-0003-1510-8666 ResearcherIDAAB-4877-2019 Scopus56703476000 | |
This section shows the teaching given in degrees, masters and other officers studies in last 6 years.
| Subject and involved studies | Type | Distance hours | Total hours |
|---|---|---|---|
| Anatomy of the Organs of Hearing and Speech | Core | 0 | 15 |
| Cell Culture Techniques | Optional | 0 | 10 |
| Cellular and Tissue Engineering | Compulsory | 0 | 7 |
| Histological Techniques | Optional | 0 | 9 |
| Nanotechnology in Medicine | Optional | 0 | 15.5 |
| Protein Analysis and Handling Techniques | Optional | 0 | 7 |
| Stem Cells and Cell Therapy | Optional | 0 | 9 |
| Subject and involved studies | Type | Distance hours | Total hours |
|---|---|---|---|
|
Anatomy of the Organs of Hearing and Speech
Degree in Speech Therapy
|
Core | 0 | 15 |
|
Cell Culture Techniques
Master's Degree in Health Care and Research
|
Optional | 0 | 12 |
|
Cellular and Tissue Engineering
Master's in Advanced Biotechnology
|
Compulsory | 0 | 7 |
|
Histological Techniques
Master's Degree in Health Care and Research
|
Optional | 0 | 12 |
|
Master`s Dissertation: Fundamentals of Biomedical Research
Master's Degree in Health Care and Research
|
Compulsory | 0 | 4 |
|
Master's Dissertation
Master's in Molecular Cellular and Genetic Biology
|
Compulsory | 0 | 4 |
|
Master's Dissertation
Master's in Advanced Biotechnology
|
Compulsory | 0 | 4 |
|
Nanotechnology in Medicine
Degree in Nanoscience and Nanotechnology
|
Optional | 0 | 19 |
|
Protein Analysis and Handling Techniques
Master's Degree in Health Care and Research
|
Optional | 0 | 8 |
|
Stem Cells and Cell Therapy
Master's in Molecular Cellular and Genetic Biology
|
Optional | 0 | 5.5 |
| Subject and involved studies | Type | Distance hours | Total hours |
|---|---|---|---|
|
Anatomy of the Organs of Hearing and Speech
Degree in Speech Therapy
|
Core | 0 | 15 |
|
Cell Culture Techniques
Master's Degree in Health Care and Research
|
Optional | 0 | 12 |
|
Cellular and Tissue Engineering
Master's in Advanced Biotechnology
|
Compulsory | 0 | 7 |
|
Histological Techniques
Master's Degree in Health Care and Research
|
Optional | 0 | 12 |
|
Master's Dissertation
Master's in Molecular Cellular and Genetic Biology
|
Compulsory | 0 | 0 |
|
Master's Dissertation
Master's in Advanced Biotechnology
|
Compulsory | 0 | 0 |
|
Protein Analysis and Handling Techniques
Master's Degree in Health Care and Research
|
Optional | 0 | 8 |
|
Stem Cells and Cell Therapy
Master's in Molecular Cellular and Genetic Biology
|
Optional | 0 | 5.5 |
| Subject and involved studies | Type | Distance hours | Total hours |
|---|---|---|---|
|
Cell Culture Techniques
Master`s Degree in Health Care and Research
Master's Degree in Health Care and Research
(Optional)
|
Compulsory | 0 | 12 |
|
Cellular and Tissue Engineering
Master's in Advanced Biotechnology
|
Compulsory | 0 | 7.5 |
|
Histological Techniques
Master`s Degree in Health Care and Research
Master's Degree in Health Care and Research
(Optional)
|
Compulsory | 0 | 12 |
|
Master's Dissertation
Master's in Molecular Cellular and Genetic Biology
|
Compulsory | 0 | 4 |
|
Protein Analysis and Handling Techniques
Master`s Degree in Health Care and Research
Master's Degree in Health Care and Research
(Optional)
|
Compulsory | 0 | 4 |
|
Stem Cells and Cell Therapy
Master's in Molecular Cellular and Genetic Biology
|
Optional | 0 | 5.5 |
| Subject and involved studies | Type | Distance hours | Total hours |
|---|---|---|---|
|
Cell Culture Techniques
Master`s Degree in Health Care and Research
|
Compulsory | 0 | 11 |
|
Handling and Analysis Techniques for Proteins
Master`s Degree in Health Care and Research
|
Compulsory | 0 | 12.5 |
|
Histological Techniques
Master`s Degree in Health Care and Research
|
Compulsory | 0 | 9 |
| Subject and involved studies | Type | Distance hours | Total hours |
|---|---|---|---|
|
Cell Culture Techniques
Master`s Degree in Health Care and Research
|
Compulsory | 0 | 9 |
|
Handling and Analysis Techniques for Proteins
Master`s Degree in Health Care and Research
|
Compulsory | 0 | 11 |
|
Histological Techniques
Master`s Degree in Health Care and Research
|
Compulsory | 0 | 11 |
|
Scientific Seminars
Master`s Degree in Health Care and Research
|
Compulsory | 0 | 3 |
|
Work Placement in a Research Group
Master`s Degree in Health Care and Research
|
Compulsory | 0 | 4 |
Directed or codirected by current teacher since 2013 year.
| Development of new non-viral systems for genetic modification in senescent cells |
| Ferroptosis: new therapeutic approach for epithelial ovarian cancer |
| Non-viral systems based on niosomes as new tools for senescent cells gene transfer |
| Study of new regulators in inflamm-aging |
| Effect of miR-21 over-expression on immunology profile of mesenchymal stem cells |
| New non-viral system development for genetic modification of mesenchymal stem cells |
| Role of p65/RelA in cellular senescence and inflamation |
Select merit type and year to query research merits.
CONTRATO RAMÒN Y CAJAL
| Funding entity | Ministerio de Economía y Competitividad (MINECO) |
| Type | Contrato |
| Dates | From 01/01/2023 to 31/01/2028 |
AYUDA INTALENT-UDC
| Funding entity | INDITEX-UDC INTALENT PROGRAMA |
| Type | Proyecto Programas Autonomicos |
| Dates | From 01/01/2023 to 01/01/2025 |
AYUDAS PARA LA CONSOLIDACIÓN Y ESTRUTURACIÓN DE UNIDADES DE INVESTIGACIÓN COMPETITIVAS. GPC 2023
| Funding entity | Consellería de Cultura, Educación e Ordenación Universitaria |
| Main researches | Silvia María Díaz Prado |
| Type | Proyecto Programas Autonomicos |
| Dates | From 01/01/2023 to 20/11/2025 |
ESTUDO DE NOVOS MECANISMOS MOLECULARES E CELULARES DA RESISTENCIA Á FERROPTOSE NAS CÉLULAS SENESCENTES PARA O TRATAMENTO DE ENFERMIDADES ASOCIADAS Á IDADE E PROXERIA.(Proxecto Excelencia 2023)
| Funding entity | CONSELLERIA DE EDUCACIÓN, UNIVERSIDADE E FORMACIÓN PROFESIONAL |
| Main researches | Juan Antonio Fafián Labora |
| Type | Proyecto Programas Autonomicos |
| Dates | From 01/01/2023 to 20/11/2027 |
Discovery new therapeutic pathways involved in the paracrine ferrotosis mediated by small extraclelular vesicles in epithelial ovarian cancer
| Funding entity | Universidade da Coruña (UDC) |
| Type | Proyecto Otros Programas |
| Dates | From 01/11/2021 to 31/10/2022 |
Plasmalogens, exosomes and autophagy in aging and neurodegeneration
| Funding entity | Ministerio de Economía y Competitividad (MINECO) |
| Main researches | JOSE ANTONIO RODRÍGUEZ NAVARRO |
| Type | Proyecto Programas Nacionales |
| Dates | From 01/01/2021 to 31/01/2024 |
AXUDAS A COMPLETAR A ETAPA POSTDOCTORAL POR LA XUNTA DE GALICIA
| Funding entity | Xunta de Galicia |
| Type | Contrato |
| Dates | From 01/04/2021 to 31/12/2022 |
Determination of the senescence associated secretory phenotype (SASP) regulated by the extracellular vesicles biogenesis pathway Rab27a
| Funding entity | ProteoRed ISCIII |
| Type | Proyecto Programas Nacionales |
| Dates | From 30/06/2020 to 30/06/2021 |
Axudas para a consolidación e estruturación de unidades de investigación competitivas-GPC
| Funding entity | Consellería de Educación e Ordenación Universitaria |
| Main researches | Díaz Pardo, Silvia |
| Type | Proyecto Programas Autonomicos |
| Dates | From 01/01/2020 to 31/12/2023 |
Terapia celular con microRNA y vesículas extracelulares para el tratamiento de la inflamación crónica en un modelo OA (Terapia libre de células)
| Funding entity | Ministerio de Ciencia, Innovación y Universidades |
| Type | Proyecto Programas Nacionales |
| Dates | From 30/07/2020 to 30/07/2023 |
ZEBRAGING DE LAS Ayudas para proyectos Semilla colaborativos entre grupos de la AE CICA-INIBIC
| Funding entity | CICA - Centro de Investigaciones Científicas Avanzadas |
| Main researches | MARIA ARUFE |
| Type | Proyecto Programas Autonomicos |
| Dates | From 22/11/2019 to 22/11/2020 |
Study of antioxidant potential of small extracellular vesicles
| Funding entity | BARTS CHARITY |
| Type | Proyecto Internacional |
| Dates | From 01/12/2019 to 01/12/2020 |
Contrato Posdoctoral por la Xunta de Galicia Modalidad A (Juan Antonio Fafián Labora)
| Funding entity | Consellería de Cultura, Educación e Ordenación Universitaria |
| Main researches | Juan Antonio Fafián Labora |
| Type | Contrato |
| Dates | From 30/06/2017 to 31/12/2020 |
Study of Ferroptosis Transmission by Small Extracellular Vesicles in Epithelial Ovarian Cancer Cells
| Authors | Carmen Alarcón-Veleiro, Rocío Mato-Basalo, Sergio Lucio-Gallego, Andrea Vidal-Pampín, María Quindós-Varela, T. Al-Qatarneh, Germán Berrecoso, Ángel Vizoso-Vázquez, M. Arufe, Fafián-Labora J |
| Journal | ANTIOXIDANTS Vol. 12 (pages 183 to 183) |
| DOI | https://doi.org/10.3390/antiox12010183 |
Development of new non-viral systems for genetic modification of senescent cells
| Authors | López-Seijas, Junquera, Miranda-Balbuena, Diego, Iglesias-Fente, Alba, Sacristán-Santos, Marta, Carballo-Pedrares, Natalia, M. Arufe, Rey-Rico, A, Fafián-Labora J |
| Journal | MOLECULAR THERAPY-NUCLEIC ACIDS |
| DOI | https://doi.org/10.1016/j.omtn.2023.03.010 |
Therapy free of cells vs human mesenchymal stem cells from umbilical cord stroma to treat the inflammation in OA.
| Authors | Rocío Mato-Basalo, Sergio Lucio-Gallego, Lucía Silva-Fernández, Alba González-Rodríguez, Fco. Javier de Toro, Juan Antonio Fafián Labora, María C Arufe |
| Journal | CELLULAR AND MOLECULAR LIFE SCIENCES |
| DOI | https://doi.org/10.1007/s00018-022-04580-z |
Genome wide CRISPR/Cas9 screen identifies the coagulation factor IX (F9) as a regulator of senescence
| Authors | Carpintero-Fernández Paula, Borghesan Michela, Eleftheriadou Olga, Fafián-Labora Juan, Mitchell Tom P, Yuste Alejandro, Ogrunc Mugue, Nightingale Thomas D, Mayán MD, OLoghlen Ana |
| Journal | Cell Death & Disease |
| DOI | https://doi.org/10.1038/s41419-022-04569-3 |
Therapeutic potential for regulation of the nuclear factor kappa-B Transcription Factor p65 to prevent cellular senescence and activation of pro-inflammatory in mesenchymal stem cells
| Authors | Rocío Mato-Basalo, M Morente-López, Onno J. Arntz, Fons A. J. van de Loo, Fafián-Labora J, M.C. Arufe |
| Journal | International Journal of Molecular Sciences |
| DOI | https://doi.org/10.3390/ijms22073367 |
High-Throughput Screen Detects Calcium Signaling Dysfunction in Hutchinson-Gilford Progeria Syndrome
| Authors | Juan A Fafián-Labora, Miriam Morente-López, Fco Javier de Toro, María C Arufe |
| Journal | International Journal of Molecular Sciences Vol. 22 Num. 14 |
| DOI | https://doi.org/10.3390/ijms22147327 |
Mesenchymal Stem Cell-Derived Extracellular Vesicle Isolation and Their Protein Cargo Characterization
| Authors | Morente-López M, Fafián-Labora J, Carrera M, de Toro-Santos, F.J., Gil C, Mateos J, M. Arufe |
| Journal | Methods Mol Biol Vol. 2259 (pages 3 to 12) |
| DOI | https://doi.org/10.1007/978-1-0716-1178-4_1 |
NF-¿B/IKK activation by small extracellular vesicles within the SASP
| Authors | Fafián-Labora Juan, OLoghlen Ana |
| Journal | Aging Cell |
| DOI | https://doi.org/10.1111/acel.13426 |
Influence of mesenchymal stem cell-derived extracellular vesicles in vitro and their role in ageing
| Authors | Juan Fafián-Labora, M. Morente-López, MJ Sánchez-Dopico, O. J. Arntz, F. A. J. van de Loo, de Toro-Santos, F.J., M. Arufe |
| Journal | Stem Cell Research & Therapy Vol. 11 Num. 3 |
| DOI | https://doi.org/10.1186/s13287-019-1534-0. |
Small Extracellular Vesicles Have GST Activity and Ameliorate Senescence-Related Tissue Damage
| Authors | Fafián-Labora J, Rodríguez-Navarro JA |
| Journal | CELL METABOLISM (pages 71 to 86) |
| DOI | https://doi.org/10.1016/j.cmet.2020.06.004 |
Classical and Nonclassical Intercellular Communication in Senescence and Ageing
| Authors | Fafián-Labora J |
| Journal | TRENDS IN CELL BIOLOGY (pages 628 to 639) |
| DOI | https://doi.org/10.1016/j.tcb.2020.05.003 |
Extracellular vesicles as potential tools for regenerative therapy
| Authors | Rodríguez-Navarro JA |
| Journal | Molecular & Cellular Oncology |
| DOI | https://doi.org/10.1080/23723556.2020.1809958 |
Effect of aging on behaviour of mesenchymal stem cells
| Authors | Fafián-Labora JA, Morente-López M, MC Arufe |
| Journal | World J Stem Cells |
| DOI | https://doi.org/10.4252/wjsc.v11.i6.337 |
Small Extracellular Vesicles Are Key Regulators of Non-cell Autonomous Intercellular Communication in Senescence via the Interferon Protein IFITM3.
| Authors | Juan Fafián-Labora |
| Journal | Cell Reports |
| DOI | https://doi.org/10.1016/j.celrep.2019.05.095 |
FASN activity is important for the initial stages of the induction of senescence
| Authors | Juan Fafián-Labora, Paula Carpintero-Fernández, Samuel JD Jordan, Tamanna Shikh-Bahae, Sana Mohammad Abdullah, Midusa Mahenthiran, José Antonio Rodríguez-Navarro, Maria Victoria Niklison-Chirou |
| Journal | Cell Death & Disease |
| DOI | https://doi.org/10.1038/s41419-019-1550-0 |
Next-Generation Sequencing and Quantitative Proteomics of Hutchinson-Gilford progeria syndrome-derived cells point to a role of nucleotide metabolism in premature aging
| Authors | Mateos J, Juan Fafián-Labora, Morente-López M, Lesende-Rodríguez IA, L. Monserrat, Ódena MA, E. de Oliveira, de Toro-Santos, F.J., MC Arufe |
| Journal | PLOS ONE |
| DOI | https://doi.org/10.1371/journal.pone.0205878 |
Effect of age on pro-inflammatory miRNAs contained in mesenchymal stem cells-derivaded extracellular vesicles
| Authors | J Fafián-Labora, I. Rodríguez-Lesende, P. Fernández-Pernas, S. Sangiao-Alvarellos, L. Monserrat, O. Arntz, F. Vand de Loo, J Mateos, M.C. Arufe |
| Journal | SCIENTIFIC REPORTS Vol. 7 |
| DOI | https://doi.org/10.1038/srep43923. |
BIODISTRIBUTION AND IMMUNOGENICITY OF ALLOGENEIC MESENCHYMAL STEM CELLS IN A RAT MODEL OF INTRAARTICULAR CHONDROCYTE XENOTRANSPLANTATION
| Authors | Maribel Marquina, Javier A. Collado, Magdiel Pérez-Cruz, Pablo Fernández-Pernas, Juan Fafián-Labora, Fco. Blanco, Rafael Mañez, María C. Arufe, Cristina Costa |
| Journal | FRONTIERS IN IMMUNOLOGY |
| DOI | https://doi.org/10.3389/fimmu.2017.01465 |
Technical Advances to Study Extracellular Vesicles.
| Authors | Fafián-Labora J, Carpintero-Fernández P |
| Journal | Frontiers in Cell and Developmental Biology |
3, 3',5-Triiodo-L-Thyronine Increases In Vitro Chondrogenesis of Mesenchymal Stem Cells from Human Umbilical Cord Stroma Through SRC2
| Authors | P Fernández-Pernas, J Fafián-Labora, I. Lesende-Rodriguez, J. Mateos, A de la Fuente, I. Fuentes, F.J. De Toro Santos, Fco. Blanco, MC Arufe |
| Journal | Journal of Cellular Biochemistry Vol. 117 Num. 9 (pages 2097 to 2108) |
| DOI | https://doi.org/10.1002/jcb.25515 |
iTRAQ-based analysis of progerin expression reveals mitochondrial dysfunction, reactive oxygen species accumulation and altered proteostasis
| Authors | J Mateos, A. Landeira-Abia, JA Fafián-Labora, P Fernández-Pernas, I Lesende-Rodríguez, P Fernández-Puente, M Fernández-Moreno, A Delmiro, MA Martín, Fco Blanco, MC Arufe |
| Journal | Stem Cell Research & Therapy Vol. 6 Num. 1 |
| DOI | https://doi.org/10.1186/s13287-015-0110-5 |
Influence of age on rat bone marrow mesenchymal stem cells potential
| Authors | J Fafián-Labora, P. Fernández-Pernas, I. Fuentes, N Oreiro, Fco. J. De Toro, S. Sangiao-Alvarellos, J. Mateos, MC Arufe |
| Journal | SCIENTIFIC REPORTS |
| DOI | https://doi.org/10.1038/srep16765 |
Development of new non-viral systems for genetic modification of senescent cells
Cellular Aging and Metabolism Symposium (CAMS) 2022
International
| Authors | Miranda- Balbuena, D, López-Seijas, J, Sacristan-Santos, M, Carballo-Pedrares, N, MC Arufe, Rey-Rico, A, Fafián-Labora J |
| Place | Coruña, A (España) |
Development of new non-viral systems for genetic modification of senescent cells
European Society of Gene and Cell Therapy (ESGCT) & British Society of Gene and Cell Therapy (BSGCT)
International
| Authors | Miranda-Balbuena, D, Lopez-Seijas, J, Sacristan-Santos, M, Carballo-Pedrares, N, MC Arufe, Fafián-Labora J, Rey-Rico, A |
| Place | Edimburgo (Reino Unido) |
Production of knockout models in two established cell line for the study of ferroptosis in ovarian cancer
44º SEBBM
National
| Authors | T. Al-Qatarneh, Cora Rey-Souto, Rocío Mato-Basalo, M. Arufe, Juan Fafián-Labora, Ángel Vizoso-Vázquez |
| Place | Málaga (España) |
Study of ferroptosis transmission by small extracellular vesicles in epithelial ovarian cancer cells
18th ASEICA INTERNATIONAL CONGRESS
International
| Authors | Alarcón-Veleiro C, Mato-Basalo Rocío, Lucio-Gallego Sergio, Vidal-Pampín Andrea, Quindos-Varela María, Al-Qatarneh Thamer, Vizoso-Vázquez Ángel, M. Arufe, Fafián-Labora Juan |
| Place | Santiago de Compostela (España) |
Role of miR-21 in Therapy free of cells vs mesenchymal stem cells to treat the inflammation in OA model
Cellular Aging and Metabolism Symposium (CAMS) 2022
International
| Authors | Morente-López Miriam, Mato-Basalo Rocío, Lucio-Gallego Sergio, Silva Lucía, García Sánchez Alba, De Toro Francisco Javier, Fafián-Labora Juan, M. Arufe |
| Place | Coruña, A (España) |
STUDY OF FERROPTOSIS TRANSMISSION BY SMALL EXTRACELLULAR VESICLES IN EPITHELIAL OVARIAN CANCER CELLS
CIMUS SYMPOSIUM 1ST EDITION
Autonomous
| Authors | Alarcón-Veleiro Carmen, Mato-Basalo Rocío, Lucio-Gallego Sergio, Quindos-Varela María, Al-Qatarneh Thamer, Ángel Vizoso-Vázquez, M. Arufe, Fafián-Labora Juan |
| Place | Santiago de Compostela (España) |
Senescence based on the purine metabolism, new target to treat age-related diseases
CIMUS SYMPOSIUM 1ST EDITION
Autonomous
| Authors | Mato-Basalo Rocío, Lucio-Gallego Sergio, Alarcón-Veleiro Carmen, Fafián-Labora Juan, M. Arufe |
| Place | Santiago de Compostela (España) |
New regulators of senescence-associated secretory phenotype mediated by small extracellular vesicles as senomorphics targets to treat age-related disease
CIMUS SYMPOSIUM 1ST EDITION
Autonomous
| Authors | Lucio-Gallego Sergio, Mato-Basalo Rocío, Alarcón-Veleiro Carmen, Carrera Mónica, Gil Concha, Mateos Jesús, M. Arufe, Fafián-Labora Juan |
| Place | Santiago de Compostela (España) |
Undiscovered of regulators of senescence-associated secretory phenotype mediated by small extracellular vesicles
MOLECULAR, CELLULAR AND ORGANISMAL DRIVERS OF AGING
International
| Authors | Lucio-Gallego Sergio, Mato-Basalo Rocío, Alarcón-Veleiro Carmen, Carrera Mónica, Gutiérrez Lola, Gil Concha, Mateos Jesús, M. Arufe, Fafián-Labora Juan |
| Place | Madrid (España) |
Therapy free of cells vs human mesenchymal stem cells from umbilical cord stroma to treat the inflammation in OA
European Society of Gene and Cell Therapy (ESGCT) & British Society of Gene and Cell Therapy (BSGCT)
International
| Authors | Morente-López Miriam, Mato-Basalo Rocío, Lucio-Gallego Sergio, Silva Lucía, García-Sánchez Alba, de Toro-Santos, F.J., Fafián-Labora Juan, M. Arufe |
| Place | Edimburgo (Reino Unido) |
Effect of miR-21 into mesenchymal stem cells -derived extracellular vesicles behaviour on inflamm-aging
6th GEIVEX SYMPOSIUM
National
| Authors | Morente-López M, Mato-Basalo Rocío, Carrera Mónica, Gil Concha, Mateos Jesús, Fafián-Labora Juan, M. Arufe |
| Place | Santiago de Compostela (España) |
Effect of miR-21 into mesenchymal stem cells -derived extracellular vesicles behaviour on inflammaging
6th GEIVEX SYMPOSIUM
National
| Authors | Morente-López Miriam, Mato-Basalo Rocío, Gil Concha, Carrera Mónica, Fafián-Labora Juan, Mateos Jesús, M. Arufe |
| Place | Santiago de Compostela (España) |
Ferroptosis transmission by small extracellular vesicles in epithelial ovarian cancer cells
6th GEIVEX SYMPOSIUM
National
| Authors | Alarcón-Veleiro Carmen, Mato-Basalo Rocío, Lucio-Gallego Sergio, Quindos-Varela María, Al-Qatarneh Thamer, Vizoso-Vázquez Ángel, M. Arufe, Fafián-Labora Juan |
| Place | Santiago de Compostela (España) |
STUDY OF FERROPTOSISTRANSMISSION BY SMALL EXTRACELLULARVESICLES IN EPITHELIAL OVARIAN CANCERCELLS
VIII EDITION BIOMEDICAL CANCER RESEARCH CONFERENCE
Autonomous
| Authors | Alarcón-Veleiro Carmen, Mato-Basalo Rocío, Lucio-Gallego Sergio, Quindos-Varela María, Al-Qatarneh Thamer, Vizoso-Vázquez Ángel, M. Arufe, Fafián-Labora Juan |
| Place | Coruña, A (España) |
Roleof miR-21 onMSC-derived EV and their paracrine effect
ISEV 2022
International
| Authors | Morente-López Miriam, Mato-Basalo Rocío, Miranda Quintana María del Pilar, Lucio-Gallego Sergio, Fafián-Labora Juan, M. Arufe |
| Place | Lyon (Francia) |
Development of senomorphics based on intercellular communication through sEV to rejuvenate senescent mesenchymal stem cells
ISEV 2022
International
| Authors | Mato-Basalo Rocío, Lucio-Gallego Sergio, Sacristán-Santos Marta, Miranda Quintana María del Pilar, Morente-López Miriam, M. Arufe, Fafián-Labora Juan |
| Place | Lyon (Francia) |
Undiscovery of regulators of senescence-associated secretory phenotype mediated by small extracellular vesicles
PROTEO VILAMOURA 2022
International
| Authors | Fafián-Labora Juan |
| Place | Vilamoura (Portugal) |
Study of ferroptosis transmission by small extracellular vesicles in epithelial ovarian cancer cells
SEBBM 2022
National
| Authors | Alarcón-Veleiro Carmen, Mato-Basalo Rocío, Lucio-Gallego Sergio, Quindos-Varela María, Al-Qatarneh Thamer, Vizoso-Vázquez Ángel, M. Arufe, Fafián-Labora Juan |
| Place | Málaga (España) |
Senescence based on the purine metabolism, new target to treat age-related diseases
SEBBM 2022
National
| Authors | Mato-Basalo Rocío, Lucio-Gallego Sergio, Alarcón-Veleiro Carmen, M. Arufe, Fafián-Labora Juan |
| Place | Málaga (España) |
Effect of miR-21 into mesenchymal stem cells - derived extracellular vesicles on inflamm-aging
SEBBM 2022
National
| Authors | Morente-López Miriam, Mato-Basalo Rocío, Gil Concha, Carrera Mónica, Fafián-Labora Juan, Mateos Jesús, M. Arufe |
| Place | Málaga (España) |
New regulators of senescence-associated secretory phenotype mediated by small extracellular vesicles as senomorphic targets to treat age-related disease
SEBBM 2022
National
| Authors | Lucio-Gallego Sergio, Mato-Basalo Rocío, Alarcón-Veleiro Carmen, Carrera Mónica, Gutiérrez Lola, Gil Concha, Mateos Jesús, M. Arufe, Fafián-Labora Juan |
| Place | Málaga (España) |
Study of ferroptosis transmission by small extracellular vesicles in epithelial ovarian cancer cells
SETGYC 11th BIENNIAL CONGRESS
National
| Authors | Alarcón-Veleiro Carmen, Mato-Basalo Rocío, Lucio-Gallego Sergio, Quindos-Varela María, Al-Qatarneh Thamer, Vizoso-Vázquez Ángel, M. Arufe, Fafián-Labora Juan |
| Place | Sevilla (España) |
Therapy free of cells vs human mesenchymal stem cells from umbilical cord stroma to treat the inflammation in OA
SETGYC 11th BIENNIAL CONGRESS
National
| Authors | Morente-López Miriam, Mato-Basalo Rocío, Lucio-Gallego Sergio, Silva Lucía, García Sánchez Alba, de Toro-Santos, F.J., Fafián-Labora Juan, M. Arufe |
| Place | Sevilla (España) |
ROLE OF SMALL EXTRACELLULAR VESICLES IN AGEING AND CELLULAR SENESCENCE
UKEV FORUM 2020
International
| Authors | Fafián-Labora Juan |
| Place | LONDRÉS (Reino Unido) |
EL PAPEL DE LAS VESÍCULAS EXTRACELULARES EN ENVEJECIMIENTO Y REJUVENECIMIENTO
AGING AND AGE-RELATED DISEASES: FROM MECHANISMS TO ADVANCED THERAPIES
Autonomous
| Authors | Fafián-Labora Juan |
| Place | Coruña, A (España) |
Development of senomorphics based on intercellular communication to treat agerelated disease
GEIVEX/TeNTaCLES 2021 MINISYMPOSIUM
National
| Authors | Fafián-Labora Juan, Mato-Basalo Rocío, Lucio-Gallego Sergio, Sacristán-Santos Marta, Miranda Quintana María del Pilar, López-Morente Miriam, M. Arufe |
| Place | Madrid (España) |
Development of senomorphics based on intercellular communication to treat age-related disease
6th International Cell Senescence Association (ICSA) Conference
International
| Authors | Mato-Basalo Rocío, Lucio-Gallego Sergio, Sacristán-Santos Marta, Miranda-Quintana María del Pilar, Morente-López Miriam, M. Arufe, Fafián-Labora Juan |
| Place | Osaka (Japón) |
Role of Purine metabolism in cellular senescence and ageing
SEBBM 2021
National
| Authors | Fafián-Labora Juan, Mato-Basalo Rocío, Miranda Quintana María del Pilar, Sacristán-Santos Marta, VAN DE LOO FONS, ARNTZ ONNO, M. Arufe |
| Place | Barcelona (España) |
Role of small extracellular vesicles in ageing and cellularsenescence
YOUNG ICSA SEMINAR 2021
International
| Authors | Fafián-Labora Juan |
| Place | Londrés (Reino Unido) |
Proteomic study of mesenchymal stem cells derived esoxomes modified using miR.
Annual Meeting ISEV 2020
International
| Authors | Miriam Morente-López, Juan A. Fafián-Labora, Jesús Mateos, Mónica Carrera, María Arufe |
| Organization | International Society for Extracellular Vesicles |
| Place | Coruña, A (España) |
Purine-metabolism: new regulator of senescence associated secretory phenotype mediated by exosome-like particles
MINISIMPOSIUM GEIVEX-TENTACLES-UFV 2020
National
| Authors | Juan Fafián-Labora, Mato Basalo R, Miriam Morente-López, Arntz O, Van de Loo FJ, María C Arufe |
| Organization | GEIVEX |
| Place | Madrid (España) |
Proteomic study of mesenchymal stem cells derived exosomes
PROTEOVIEDO 2020
Autonomous
| Authors | Morente-López Miriam, Fafián-Labora Juan, Mateos Jesús, Gutiérrez Lola, HERMÁEZ LUISA, Gil Concha, Carrera Mónica, M. Arufe |
| Place | Oviedo (España) |
¿Small extracellular vesicles in cellular senescence and ageing¿
GENOMICS AND CHILD HEALTH VIRTUAL RESEARCH SEMINAR
International
| Authors | Fafián-Labora Juan |
| Place | Londrés (Reino Unido) |
El papel de las vesículas extracelulares en envejecimiento celular
HAPPY HOUR CICA-INIBIC 2020
Autonomous
| Authors | Fafián-Labora Juan |
| Place | Coruña, A (España) |
Novel regulators of senescence: in disease and health
International Cellular Senescence Association Conference 2019
International
| Authors | Fafián-Labora J |
| Place | Atenas (Grecia) |
TERAPIA CELULAR CON MICRO-ARN E EXOSOMAS PARA O TRATAMENTO DA INFLAMACIÓN CRÓNICA NUN MODELO DE ARTROSE
BIOINTEGRASAÙDE 2019
Autonomous
| Authors | Morente-López Miriam, Fafián-Labora Juan, M. Arufe |
| Place | Santiago de Compostela (España) |
Small Extracellular Vesicles in senescence and ageing
EXTRACELLULAR VESICLES SYMPOSIUM
International
| Authors | Fafián-Labora Juan |
| Place | Londrés (Reino Unido) |
Role of small extracellular vesicles in ageing
ISEV 2019
International
| Authors | Fafián-Labora Juan, OLoghlen Ana, Carpintero-Fernández Paula, Eleftheriadou Olga |
| Place | KYOTO (Japón) |
Interferon protein 3 mediates paracrine senescence in human primary fibroblasts
SEBC 2019
National
| Authors | OLoghlen Ana, Fafián-Labora Juan, Borghesan Michela, Eleftheriadou Olga, Carpintero-Fernández Paula |
| Place | Badajoz (España) |
SMALL EXTRACELLULAR VESICLES ARE JEY REGULATORS OF NON-CELL AUTONOMOUS INTERCELLULAR COMMUNICATION IN SENESCENT VIA THE INTERFERON PROTEIN, IFITM3
SEMINARIO HOSPITAL RAMÓN Y CAJAL IRYCIS
National
| Authors | Fafián-Labora Juan |
| Place | Madrid (España) |
Functionality of bone marrow mesenchymal stem cell-derived extracellular vesicles on self-renewal
Annual Meeting International Society for Extracelular vesicles ISEV2018
International
| Authors | Juan Fafián-Labora, M. MOrente-López, P. Diaz-Barreiro, p. Fernández-Pernas, M.C.Arufe |
| Place | Barcelona (España) |
| DOI | https://doi.org/10.1080/20013078.2018.1461450 |
Quantitative proteomics and whole transcriptomics sequencing of Progeria- derived cells point to a key role of nucleotide metabolism in premature aging
EUPA 2018
International
| Authors | Jesús Mateos, Miriam Morente-López, Juan Fafián Labora, Iván Lesende-Rodríguez, María A. Òdena, Eliandre De Oliveira, Lorenzo Monserrat, Javier De Toro, MC Arufe |
| Organization | Sociedad Española de Proteómica |
| Place | Santiago de Compostela (España) |
The bystander effect of exosomes in ageing
ISEV 2018
International
| Authors | Borghesan Michela, Fafián-Labora Juan, Carpintero-Fernández Paula, OLoghlen Ana |
| Place | Barcelona (España) |
FASN activity is important for the initial stages of senescence induction in cells
IX REUNIÓN DE JÓVENES INVESTIGADORES EN EL EXTRANJERO 2018
International
| Authors | Fafián-Labora Juan |
| Place | Coruña, A (España) |
ROLE OF SMALL EXTRACELLULAR VESICLES IN AGEING
I JORNADA DE VESÍCULAS EXTRACELULARES
Autonomous
| Authors | Fafián-Labora Juan |
| Place | Coruña, A (España) |
ROLE OF FASN IN CELLULAR SENESCENCE
2018 William Harvey Day
International
| Authors | Fafián-Labora Juan |
| Place | Londrés (Reino Unido) |
Effect of ageing on pro-inflammatory micro-RNAs contained in MSC-derived extracellular vesicles
ISEV 2016
International
| Authors | J Fafián-Labora, P. Fernández-Pernas, Onno J. Arntz, Miranda Bennink, Fons A.J Van de Loo, María C. Arufe |
| Organization | International Society for Extracellular Vesicles |
| Place | Rotterdam (Países Bajos) |
Quantitative Proteomics and Whole Transcriptomics Sequencing of Progeria-derived Cells Point to a Key Role of IGF Signaling Pathway in Premature Aging
15th Human Proteome Organization Congress
International
| Authors | J Fafián-Labora, I. Lesende-Rodriguez, L. Monserrat, A. Odena, E. de Oliveira, MC Arufe, J. Mateos |
| Organization | HUPO |
| Place | Taipei (Taiwán) |
Proteome and Transcriptome analysis in rat bone marrow mesenchymal stem cells at different ages
6th Congress of Spanish Proteomics Society
National
| Authors | JA Fafian-Labora, Iván Lesende Rodríguez, P. Fernández Pernas, S Sangiao-Alvarellos, L Monserrat, Mateos J, MC Arufe |
| Organization | Sociedad Española de Proteómica |
| Place | Cádiz (España) |
EFFECT OF AGEING ON PRO-INFLAMMATORY MICRO-RNAS CONTAINED IN MSC-DERIVED EXTRACELLULAR VESICLES
SEMINARIO INIBIC 2016
Autonomous
| Authors | Fafián-Labora Juan |
| Place | Coruña, A (España) |
Estudio del efecto del envejecimiento sobre el proteoma de las células madre mesenquimales mediante iTRAQ
IV Jornadas Bienales de Jóvenes Investigadores en Proteómica
National
| Authors | J Fafián-Labora, J Mateos, P Fernández, S Sangiao, MC Arufe |
| Organization | Sociedad Española de Proteómica (SEProt) |
| Place | Bilbao (España) |
Role of ageing in mesenchymal stem cells behaviour
World Conference on Regenerative Medicine 2015
International
| Authors | J Fafián-Labora, P. Fernández-Pernas, J. Mateos, S. Sangiao-Alvarellos, MC Arufe |
| Organization | Fraunhofer Institute for cell therapy and immunology |
| Place | Leipzig (Alemania) |
Protemic analyis of proteome from mesenchymal stem cells at several ages
Late Summer Austrian Proteomics Seminar 2015
International
| Authors | Fafián-Labora Juan |
| Place | Viena (Austria) |
Estudio del efecto del envejecimiento sobre el proteoma de las células madre mesenquimales mediante iTRAQ
XII BIOINTEGRASAÙDE 2015
Autonomous
| Authors | Fafián-Labora Juan, Mateos, Jesús, Fernández-Pernas, Pablo, Susana Sangiao Alvarellos, M. Arufe |
| Place | Vigo (España) |
Influencia del envejecimiento en el perfil pro-inflamatorio de micro-RNAs contenidos en los exosomas procedentes de células madre mesenquimales
VI REUNIÓN JÓVENES INVESTIGADORES EN EL EXTRANJERO
International
| Authors | Fafián-Labora Juan |
| Place | Coruña, A (España) |
PROTEOMIC STUDY OF MESENCHYMAL STEM CELLS DURING AGEING BY iTRAQ
XXXV REUNIÓN BIENAL RSEQ 2015
Autonomous
| Authors | Fafián-Labora Juan |
| Place | Coruña, A (España) |
the age-related differences in the microRNA content of the extracellular vesicles and these consequences for their therapeutic potential
Seminar Radboud University medical center in Nijmegen
International
| Authors | Fafián-Labora Juan |
| Place | Nijmegen (Países Bajos) |
Quantitative proteomic analysis of rat mesenchymal stem cells at different ages
13th Human Proteome Organization World Congress (HUPO).
International
| Authors | Juan Fafián, J. Mateos, P. Fernández, S. Sangiao-Alvarellos, I Fuentes, J de Toro, F.J. Blanco, MC Arufe |
| Organization | HUPO |
| Place | Madrid (España) |
Study of the long term stability of an industrial polyamide from a contemporary artwork
The International Congress on Science and Technology for the Conservation of Culture
International
| Authors | Juan Fafián-Labora, Thais López-Morán, Arturo López-Quintela, M Lazzari |
| Place | Santiago de Compostela (España) |
Academic or management positions held by teacher.