Dr. Francisco Javier Blanco García  

The addition of albumin improves Schwann cells viability in nerve cryopreservation

INDUCED PLURIPOTENT STEM CELL FOR CARTILAGE REPAIR: CURRENT STATUS AND FUTURE PERSPECTIVES

Meta-analysis of Immunochip data of four autoimmune diseases reveals novel single-disease and cross-phenotype associations

Incident hand OA is strongly associated with reduced peripheral blood leukocyte telomere length

In vitro comprehensive analysis of VA692 a new chemical entity for the treatment of osteoarthritis

Mitochondrial DNA haplogroups associated with MRI-detected structural damage in early knee osteoarthritis

Efficacy of tocilizumab monotherapy after response to combined tocilizumab and methotrexate in patients with rheumatoid arthritis: the randomised JUST-ACT study

Clinical, Patient-Reported, and Ultrasound Outcomes from an Open-Label, 12-week Observational Study of Certolizumab Pegol in Spanish Patients with Rheumatoid Arthritis with or without Prior Anti-TNF Exposure

Osteoarthritis and atherosclerosis in joint disease

Expert Recommendations on the Interleukin 6 Blockade in Patients with Rheumatoid Arthritis

Mitochondria and mitophagy: biosensors for cartilage degradation and osteoarthritis

Intraneural IFG-1 in Cryopreserved Nerve Isografts Increase Neural Regeneration and Functional Recovery in the Rat Sciatic Nerve

Mitochondrial DNA variation and the pathogenesis of osteoarthritis phenotypes

Validation study of genetic biomarkers of response to TNF inhibitors in rheumatoid arthritis

Early and sustained efficacy with apremilast monotherapy in biological-naïve patients with psoriatic arthritis: a phase IIIB, randomised controlled trial (ACTIVE).

Recommendations for the use of parenteral methotrexate in rheumatic diseases

What did we learn from 'omics' studies in osteoarthritis

Ovine Mesenchymal Stromal Cells: Morphologic, Phenotypic and Functional Characterization for Osteochondral Tissue Engineering

Human amniotic mesenchymal stromal cells as favourable source for cartilage repair.

Hydrogen Sulfide and Inflammatory Joint Diseases

Human cartilage engineering in an in vitro repair model using collagen scaffolds and mesenchymal stromal cells

The mitocondrial inhibitor oligomycin induces an inflammatory response in the rat knee Joint

Mitochondrial DNA haplogroups influence the risk of incident knee osteoarthritis in OAI and CHECK cohorts. A meta-analysis and functional study.

A replication study and meta-analysis of mitochondrial DNA variants in the radiographic progression of knee osteoarthritis

Long-term effects of hydrogen sulfide on the anabolic-catabolic balance of articular cartilage in vitro

BIODISTRIBUTION AND IMMUNOGENICITY OF ALLOGENEIC MESENCHYMAL STEM CELLS IN A RAT MODEL OF INTRAARTICULAR CHONDROCYTE XENOTRANSPLANTATION

CD105+ mesenchymal stem cells migrate into osteoarthritis joint: an animal model.

Improved control over MSCs behavior within 3D matrices by using different cell loads in both in vitro and in vivo environments

The role of osmolarity adjusting agents in the regulation of encapsulated cell behavior to provide a safer and more predictable delivery of therapeutics

Plasma mitochondrial DNA levels are inversely associated with HIV-RNA levels and directly with CD4 counts: potential role as a biomarker of HIV replication

An MIF Promoter Polymorphism Is Associated with Susceptibility to Pulmonary Arterial Hypertension in Diffuse Cutaneous Systemic Sclerosis

MALDI mass spectrometry imaging in rheumatic diseases. Biochim Biophys Acta Proteins Proteom.

Hif-1¿ Knockdown Reduces Glycolytic Metabolism and Induces Cell Death of Human Synovial Fibroblasts Under Normoxic Conditions

Hyperlipidemic microenvironment conditionates damage mechanisms in human chondrocytes by oxidative stress

Cardiovascular disease in immune-mediated inflammatory diseases: A cross-sectional analysis of 6 cohorts

Secukinumab in Active Rheumatoid Arthritis: A Phase III Randomized, Double-Blind, Active Comparator- and Placebo-Controlled Study

Screening and Validation of Novel Biomarkers in Osteoarticular Pathologies by Comprehensive Combination of Protein Array Technologies.

Defining the proteomic landscape of rheumatoid arthritis: progress and prospective clinical applications

Recommendations by the Spanish Society of Rheumatology for the management of patients diagnosed with rheumatoid arthritis who cannot be treated with methotrexate

Lipoprotein(a) concentrations in rheumatoid arthritis on biologic therapy: Results from the CARdiovascular in rheuMAtology study project.

Discovery of circulating proteins associated to knee radiographic osteoarthritis

Hybrid Alginate¿Protein-Coated Graphene Oxide Microcapsules Enhance the Functionality of Erythropoietin Secreting C2C12 Myoblasts

A multicentric study to evaluate the use of relative retention times in targeted proteomics

Multiplexed mass spectrometry monitoring of biomarker candidates for osteoarthritis

Combined Treatment With Chondroitin Sulfate and Glucosamine Sulfate Shows No Superiority Over Placebo for Reduction of Joint Pain and Functional Impairment in Patients With Knee Osteoarthritis: A Six-Month Multicenter, Randomized, Double-Blind, Placebo-Controlled Clinical Trial

Mass spectrometry imaging: a novel technology in rheumatology

Intravenous administration of expanded allogeneic adipose-derived mesenchymal stem cells in refractory rheumatoid arthritis (Cx611): results of a multicentre, dose escalation, randomised, single-blind, placebo-controlled phase Ib/IIa clinical trial

3, 3',5-Triiodo-L-Thyronine Increases In Vitro Chondrogenesis of Mesenchymal Stem Cells from Human Umbilical Cord Stroma Through SRC2

Differentiation of human mesenchymal stromal cells cultured on collagen sponges for cartilage repair

Resveratrol lowers synovial hyperplasia, inflammatory markers, and oxidative damage in an acute antigen-induced arthritis model

Brief Report: European Mitochondrial Haplogroups Impact on Liver Fibrosis Progression Among HCV and HIV/HCV-Coinfected Patients From Northwest Spain

Diabetes-accelerated experimental osteoarthritis is prevented by autophagy activation

Generating Rho-0 Cells Using Mesenchymal Stem Cell Lines

A functional variant of TLR10 modifies the activity of NFkB and may help predict a worse prognosis in patients with rheumatoid arthritis

Specific premature epigenetic aging of cartilage in osteoarthritis

Urine metabolome profiling of immune-mediated inflammatory diseases

Brief Report: IRF4 Newly Identified as a Common Susceptibility Locus for Systemic Sclerosis and Rheumatoid Arthritis in a Cross-Disease Meta-Analysis of Genome-Wide Association Studies

A Single Nucleotide Polymorphism in the Il17ra Promoter Is Associated with Functional Severity of Ankylosing Spondylitis

A genome-wide association study identifies SLC8A3 as a susceptibility locus for ACPA-positive rheumatoid arthritis

Apremilast, an oral phosphodiesterase 4 inhibitor, in patients with psoriatic arthritis and current skin involvement: a phase III, randomised, controlled trial (PALACE 3)

Identification of IRX1 as a Risk Locus for Rheumatoid Factor Positivity in Rheumatoid Arthritis in a Genome-Wide Association Study

Effectiveness of Tapentadol Prolonged Release (PR) Compared with Oxycodone/Naloxone PR for the Management of Severe Chronic Low Back Pain with a Neuropathic Component: A Randomized, Controlled, Open-Label, Phase 3b/4 Study

Secretome analysis of human articular chondrocytes unravels catabolic effects of nicotine on the joint

Translation of clinical problems in osteoarthritis into pathophysiological research goals

A methodological approach based on gold-nanoparticles followed by matrix assisted laser desorption ionization time of flight mass spectrometry for the analysis of urine profiling of knee osteoarthritis

Insulin decreases autophagy and leads to cartilage degradation

A genome-wide association study identifies a new locus associated with the response to anti-TNF therapy in rheumatoid arthritis

Replication of PTPRC as genetic biomarker of response to TNF inhibitors in patients with rheumatoid arthritis

Gla-rich protein is involved in the cross-talk between calcification and inflammation in osteoarthritis

Combined chondroitin sulfate and glucosamine for painful knee osteoarthritis: a multicentre, randomised, double-blind, non-inferiority trial versus celecoxib

Alternative protocols to induce chondrogenic differentiation: Transforming Growth Factor-ß superfamily

iTRAQ-based analysis of progerin expression reveals mitochondrial dysfunction, reactive oxygen species accumulation and altered proteostasis

Mitochondrial DNA haplogroups modulate the radiographic progression of Spanish patients with osteoarthritis

Secukinumab, an Interleukin-17A Inhibitor, in Ankylosing Spondylitis

Long-term safety, efficacy, and quality of life in patients with juvenile idiopathic arthritis treated with intravenous abatacept for up to seven years

The Spanish biology/disease initiative within the human proteome project: Application to rheumatic diseases

Variation at interleukin-6 receptor gene is associated to joint damage in rheumatoid arthritis

Lessons from the proteomic study of osteoarthritis

Call for standardized definitions of osteoarthritis and risk stratification for clinical trials and clinical use

Proteomic Analysis of Connexin 43 Reveals Novel Interactors Related to Osteoarthritis

Improved prediction of knee osteoarthritis progression by genetic polymorphisms: the Arthrotest Study

Major histocompatibility complex associations of ankylosing spondylitis are complex and involve further epistasis with ERAP1

OARSI Clinical Trials Recommendations: Soluble biomarker assessments in clinical trials in osteoarthritis

Autophagy activation and protection from mitochondrial dysfunction in human chondrocytes

Rheumatoid arthritis response to treatment across IgG1 allotype - anti-TNF incompatibility: a case-only study

Protein classification and distribution in osteoarthritic human synovial tissue by matrix-assisted laser desorption ionization mass spectrometry imaging

Characterization of lipidic markers of chondrogenic differentiation using mass spectrometry imaging

Effect of the physicochemical properties of pure or chitosan-coated poly(L-lactic acid)scaffolds on the chondrogenic differentiation of mesenchymal stem cells from osteoarthritic patients

Integrating medical and research information: a big data approach

Articular chondrocyte network mediated by gap junctions: role in metabolic cartilage homeostasis

Influence of flap prefabrication on seeding of subcutaneously injected mesenchymal stem cells in microvascular beds in rats

Effect of hydrogen sulfide sources on inflammation and catabolic markers on interleukin 1ß-stimulated human articular chondrocytes.

Mitochondrial dysfunction promotes and aggravates the inflammatory response in normal human synoviocytes

Individual telomere length decay in patients with spondyloarthritis

Quantitative proteomic profiling of human articular cartilage degradation in osteoarthritis

A meta-analysis of genome-wide association studies identifies novel variants associated with osteoarthritis of the hip

Osteoarthritis year in review 2014: we need more biochemical biomarkers in qualification phase

Mitochondrial DNA (mtDNA) haplogroups influence the progression of knee osteoarthritis Data from the Osteoarthritis Initiative (OAI)

Analysis of autoantibody profiles in osteoarthritis using comprehensive protein array concepts

Genotypic tropism testing in proviral DNA to guide maraviroc initiation in aviremic subjects: 48-week analysis of the PROTEST study

Multifunctional hydrogel-based scaffold for improving the functionality of encapsulated therapeutic cells and reducing inflammatory response

Lack of replication of interactions between polymorphisms in rheumatoid arthritis susceptibility: case-control study

Editorial: Is it time for epigenetics in osteoarthritis?

Sequential depletion coupled to C18 sequential extraction as a rapid tool for human serum multiple profiling

Lack of replication of higher genetic risk load in men than in women with systemic lupus erythematosus

A pharmacoproteomic study confirms the synergistic effect of chondroitin sulfate and glucosamine

Cryoconservation of peptide extracts from trypsin digestion of proteins for proteomic analysis in a hospital biobank facility

Genome-wide DNA methylation analysis of articular chondrocytes reveals a cluster of osteoarthritic patients

Assessment of osteoarthritis candidate genes in a meta-analysis of nine genome-wide association studies

Biochemical evidence for gap junctions and Cx43 expression in immortalized human chondrocyte cell line: a potential model in the study of cell communication in human chondrocytes

mtDNA haplogroups and osteoarthritis in different geographic populations

Tocilizumab in patients with active rheumatoid arthritis and inadequate response to disease-modifying antirheumatic drugs or tumor necrosis factor inhibitors: subanalysis of Spanish results of an open-label study close to clinical practice

Secretome analysis of human mesenchymal stem cells undergoing chondrogenic differentiation

Crystallization and preliminary X-ray diffraction analysis of the homing endonuclease I-CvuI from Chlorella vulgaris in complex with its target DNA

A genome-wide association study follow-up suggests a possible role for PPARG in systemic sclerosis susceptibility

Surfing transcriptomic landscapes A step beyond the annotation of chromosome 16 proteome

Immunochip analysis identifies multiple susceptibility loci for systemic sclerosis

Osteoarthritis: something is moving

LC-MALDI-TOF/TOF for shotgun proteomics

Multilineage differentiation potential of cells isolated from the human amniotic membrane

Molecular profile and cellular characterization of human bone marrow mesenchymal stem cells: donor influence on chondrogenesis

Potential use of the human amniotic membrane as a scaffold in human articular carilage repair

Cell and tissue transplant strategies for joint lesions