Dra. Ana Rey Rico  

Investigador contratado no programa InTalent UDC-INDITEX (PR-PX-InTLT)

Investigación  Grupo de investigación Grupo de investigación en Terapia Celular e Medicina Rexenerativa
Liñas de investigación Aínda non figuran no xestor curricular da UDC (SUXI).
Contacto Directorio da UDC

Docencia

Docencia impartida

Neste apartado móstrase a docencia impartida en graos, mestrados e resto de titulacións oficiais ata os últimos 6 anos.

Materia e estudos en que se imparte Horas totais
Anatomía e Cinesioloxía do Movemento Humano
Grao en Ciencias da Actividade Física e do Deporte
20
Anatomía I e Histoloxía
Grao en Fisioterapia
9
Aplicación das Técnicas de Investigación en Ciencias da Saúde
Máster Universitario en Asistencia e Investigación Sanitaria
6
Técnicas de Cultivo Celular
Máster Universitario en Asistencia e Investigación Sanitaria
8,5
Técnicas de Manipulación e Análise de Ácidos Nucleicos
Máster Universitario en Asistencia e Investigación Sanitaria
20
Materia e estudos en que se imparte Horas totais
Aplicación das Técnicas de Investigación en Ciencias da Saúde 6
Estancia nun Grupo de Investigación 3
Seminarios Científicos 6
Técnicas de Cultivo Celular 8,5
Técnicas de Manipulación e Análise de Ácidos Nucleicos 20

Traballos fin de grao e mestrado

Dirixidos ou codirixidos polo/a docente desde o ano 2013.

Sistemas de administración de xenes baseados en peptidos de penetración celular para a transfección efectiva de células nai mesenquimais
Sistemas de administración de xenes para a transfección efectiva de células nai mesenquimais

Resultados da investigación

Pode consultar os méritos de investigación seleccionando un tipo de mérito e o ano.

Current Trends in Viral Gene Therapy for Human Orthopaedic Regenerative Medicine

Autores Jagadeesh Kumar Venkatesan, Rey-Rico, A, Magali Cucchiarini
Revista Tissue Engineering and Regenerative Medicine (páxs. 1 ata 11)
DOI https://doi.org/10.1007/s13770-019-00179-x

PEO-PPO-PEO Tri-Block Copolymers for Gene Delivery Applications in Human Regenerative Medicine-An Overview

Autores Rey-Rico, A, Cucchiarini, M
Revista International Journal of Molecular Sciences Vol. 19 Núm. 3
DOI https://doi.org/10.3390/ijms19030775

Effective Remodelling of Human Osteoarthritic Cartilage by sox9 Gene Transfer and Overexpression upon Delivery of rAAV Vectors in Polymeric Micelles

Autores Rey-Rico, A, Venkatesan, JK, Schmitt, G, Speicher-Mentges, S, Madry, H, Cucchiarini, M
Revista MOLECULAR PHARMACEUTICS Vol. 15 Núm. 7 (páxs. 2816 ata 2826)
DOI https://doi.org/10.1021/acs.molpharmaceut.8b00331

Chondrogenic Differentiation Processes in Human Bone-Marrow Aspirates Seeded in Three-Dimensional-Woven Poly(¿-Caprolactone) Scaffolds Enhanced by Recombinant Adeno-Associated Virus-Mediated SOX9 Gene Transfer

Autores Jagadeesh Kumar Venkatesan, FT Moutos, Rey-Rico, A, BT Estes, Janina Fisch, Gertrud Schmitt, Henning Madry, Farshid Guilak, Magali Cucchiarini
Revista HUMAN GENE THERAPY Vol. 29 Núm. 11 (páxs. 1277 ata 1286)
DOI https://doi.org/10.1089/hum.2017.165

Improved Chondrogenic Differentiation of rAAV SOX9-Modified Human MSCs Seeded in Fibrin-Polyurethane Scaffolds in a Hydrodynamic Environment

Autores Jagadeesh Kumar Venkatesan, Oliver Gardner, Rey-Rico, A, David Eglin, Mauro Alini, Martin Stoddart, Magali Cucchiarini, Henning Madry
Revista International Journal of Molecular Sciences
DOI https://doi.org/10.3390/ijms19092635

Antimicrobial Properties and Osteogenicity of Vancomycin-Loaded Synthetic Scaffolds Obtained by Supercritical Foaming

Autores Carlos García Gonzalez, Joana Barros, Rey-Rico, A, Pablo Redondo, Jose Luis Gómez Amoza, Angel Concheiro, Carmen Alvarez Lorenzo, Fernando J Monteiro
Revista ACS Applied Materials & Interfaces Vol. 10 (páxs. 3349 ata 3360)
DOI https://doi.org/10.1021/acsami.7b17375

Sustained spatiotemporal release of TGF-ß1 confers enhanced very early chondrogenic differentiation during osteochondral repair in specific topographic patterns

Autores Ann-Kathrin Asen, Lars Goebel, Rey-Rico, A, Jerome Sohier, Magali Cucchiarini, Henning Madry
Revista FASEB JOURNAL Vol. 32 (páxs. 5298 ata 5311)
DOI https://doi.org/10.1096/fj.201800105r

rAAV-mediated overexpression of TGF-beta via vector delivery in polymeric micelles stimulates the biological and reparative activities of human articular chondrocytes in vitro and in a human osteochondral defect model

Autores Rey-Rico, A, Venkatesan, JK, Schmitt, G, Concheiro, A, Madry, H, Alvarez-Lorenzo, C, Cucchiarini, M
Revista INTERNATIONAL JOURNAL OF NANOMEDICINE Vol. 12 (páxs. 6985 ata 6996)
DOI https://doi.org/10.2147/ijn.s144579

Supramolecular polypseudorotaxane gels for controlled delivery of rAAV vectors in human mesenchymal stem cells for regenerative medicine

Autores Rey-Rico, A, Babicz, H, Madry, H, Concheiro, A, Alvarez-Lorenzo, C, Cucchiarini, M
Revista INTERNATIONAL JOURNAL OF PHARMACEUTICS Vol. 531 Núm. 2 (páxs. 492 ata 503)
DOI https://doi.org/10.1016/j.ijpharm.2017.05.050

Peripheral blood aspirates overexpressing IGF-I via rAAV gene transfer undergo enhanced chondrogenic differentiation processes

Autores Frisch, J, Orth, P, Rey-Rico, A, Venkatesan, JK, Schmitt, G, Madry, H, Kohn, D, Cucchiarini, M
Revista JOURNAL OF CELLULAR AND MOLECULAR MEDICINE Vol. 21 Núm. 11 (páxs. 2748 ata 2758)
DOI https://doi.org/10.1111/jcmm.13190

Effects of combined rAAV-mediated TGF-beta and sox9 gene transfer and overexpression on the metabolic and chondrogenic activities in human bone marrow aspirates.

Autores Tao, Ke, Rey-Rico, A, Frisch, Janina, Venkatesan, Jagadeesh Kumar, Schmitt, Gertrud, Madry, Henning, Lin, Jianhao, Cucchiarini, Magali
Revista Journal of experimental orthopaedics Vol. 4 Núm. 1
DOI https://doi.org/10.1186/s40634-017-0077-5

Impact of mechanical stimulation on the chondrogenic processes in human bone marrow aspirates modified to overexpress sox9 via rAAV vectors.

Autores Venkatesan, Jagadeesh K, Frisch, Janina, Rey-Rico, A, Schmitt, Gertrud, Madry, Henning, Cucchiarini, Magali
Revista Journal of experimental orthopaedics Vol. 4 Núm. 1
DOI https://doi.org/10.1186/s40634-017-0097-1

Smart and Controllable rAAV Gene Delivery Carriers in Progenitor Cells for Human Musculoskeletal Regenerative Medicine with a Focus on the Articular Cartilage.

Autores Rey-Rico, A, Magali Cucchiarini
Revista Current Gene Therapy Vol. 17 Núm. 2
DOI https://doi.org/10.2174/1566523217666170510162459

Hydrogels for precision meniscus tissue engineering: a comprehensive review.

Autores Rey-Rico, A, Cucchiarini M, Madry H
Revista CONNECTIVE TISSUE RESEARCH Vol. 58 Núm. 3-4 (páxs. 317 ata 328)
DOI https://doi.org/10.1080/03008207.2016.1276576.

Effects of rAAV-mediated FGF-2 gene transfer and overexpression upon the chondrogenic differentiation processes in human bone marrow aspirates.

Autores Frisch, Janina, Venkatesan, Jagadeesh K, Rey-Rico, A, Zawada, Adam M, Schmitt, Gertrud, Madry, Henning, Cucchiarini, Magali
Revista Journal of experimental orthopaedics Vol. 3 Núm. 1
DOI https://doi.org/10.1186/s40634-016-0052-6

Biomedical-grade, high mannuronic acid content (BioMVM) alginate enhances the proteoglycan production of primary human meniscal fibrochondrocytes in a 3-D microenvironment

Autores Rey-Rico, A, Klich, A, Cucchiarini, M, Madry, H
Revista Scientific Reports Vol. 6
DOI https://doi.org/10.1038/srep28170

TGF- gene transfer and overexpression via rAAV vectors stimulates chondrogenic events in human bone marrow aspirates

Autores Frisch, J, Rey-Rico, A, Venkatesan, JK, Schmitt, G, Madry, H, Cucchiarini, M
Revista JOURNAL OF CELLULAR AND MOLECULAR MEDICINE Vol. 20 Núm. 3 (páxs. 430 ata 440)
DOI https://doi.org/10.1111/jcmm.12774

rAAV-mediated combined gene transfer and overexpression of TGF- and SOX9 remodels human osteoarthritic articular cartilage

Autores Tao, K, Rey-Rico, A, Frisch, J, Venkatesan, JK, Schmitt, G, Madry, H, Lin, JH, Cucchiarini, M
Revista JOURNAL OF ORTHOPAEDIC RESEARCH Vol. 34 Núm. 12 (páxs. 2181 ata 2190)
DOI https://doi.org/10.1002/jor.23228

rAAV-mediated overexpression of sox9, TGF-beta and IGF-I in minipig bone marrow aspirates to enhance the chondrogenic processes for cartilage repair

Autores Frisch, J, Rey-Rico, A, Venkatesan, JK, Schmitt, G, Madry, H, Cucchiarini, M
Revista GENE THERAPY Vol. 23 Núm. 3 (páxs. 247 ata 255)
DOI https://doi.org/10.1038/gt.2015.106

Co-overexpression of TGF-beta and SOX9 via rAAV gene transfer modulates the metabolic and chondrogenic activities of human bone marrow-derived mesenchymal stem cells

Autores Tao, K, Frisch, J, Rey-Rico, A, Venkatesan, JK, Schmitt, G, Madry, H, Lin, JH, Cucchiarini, M
Revista Stem Cell Research & Therapy Vol. 7
DOI https://doi.org/10.1186/s13287-016-0280-9

Hydrogel-Based Controlled Delivery Systems for Articular Cartilage Repair

Autores Rey-Rico, A, Henning Madry, Magali Cucchiarini
Revista BioMed Research International
DOI https://doi.org/10.1155/2016/1215263

Recent tissue engineering-based advances for effective rAAV-mediated gene transfer in the musculoskeletal system

Autores Magali Cucchiarini, Rey-Rico, A
Revista Bioengineered Vol. 7 Núm. 3
DOI https://doi.org/10.1080/21655979.2016.1187347

Effective genetic modification and differentiation of hMSCs upon controlled release of rAAV vectors using alginate/poloxamer composite systems

Autores Diaz-Rodriguez, P, Rey-Rico, A, Madry, H, Landin, M, Cucchiarini, M
Revista INTERNATIONAL JOURNAL OF PHARMACEUTICS Vol. 496 Núm. 2 (páxs. 614 ata 626)
DOI https://doi.org/10.1016/j.ijpharm.2015.11.008

PEO-PPO-PEO micelles as effective rAAV-mediated gene delivery systems to target human mesenchymal stem cells without altering their differentiation potency

Autores Rey-Rico, A, Venkatesan, JK, Frisch, J, Rial-Hermida, I, Schmitt, G, Concheiro, A, Madry, H, Alvarez-Lorenzo, C, Cucchiarini, M
Revista ACTA BIOMATERIALIA Vol. 27 (páxs. 42 ata 52)
DOI https://doi.org/10.1016/j.actbio.2015.08.046

Chondrogenic Differentiation Processes in Human Bone Marrow Aspirates upon rAAV-Mediated Gene Transfer and Overexpression of the Insulin-Like Growth Factor I

Autores Frisch, J, Rey-Rico, A, Venkatesan, JK, Schmitt, G, Madry, H, Cucchiarini, M
Revista TISSUE ENGINEERING PART C-METHODS Vol. 21 (páxs. 2460 ata 2471)
DOI https://doi.org/10.1089/ten.tea.2014.0679

Effective and durable genetic modification of human mesenchymal stem cells via controlled release of rAAV vectors from self-assembling peptide hydrogels with a maintained differentiation potency

Autores Rey-Rico, A, Venkatesan, JK, Frisch, J, Schmitt, G, Monge-Marcet, A, Lopez-Chicon, P, Mata, A, Semino, C, Madry, H, Cucchiarini, M
Revista ACTA BIOMATERIALIA Vol. 18 (páxs. 118 ata 127)
DOI https://doi.org/10.1016/j.actbio.2015.02.013

Adapted chondrogenic differentiation of human mesenchymal stem cells via controlled release of TGF-beta 1 from poly(ethylene oxide)-terephtalate/poly(butylene terepthalate) multiblock scaffolds

Autores Rey-Rico, A, Venkatesan, JK, Sohier, J, Moroni, L, Cucchiarini, M, Madry, H
Revista JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A Vol. 103 Núm. 1 (páxs. 371 ata 383)
DOI https://doi.org/10.1002/jbm.a.35181

Determination of effective rAAV-mediated gene transfer conditions to support chondrogenic differentiation processes in human primary bone marrow aspirates

Autores Rey-Rico, A, Frisch, J, Venkatesan, JK, Schmitt, G, Madry, H, Cucchiarini, M
Revista GENE THERAPY Vol. 22 Núm. 1 (páxs. 50 ata 57)
DOI https://doi.org/10.1038/gt.2014.90

Supramolecular cyclodextrin-based drug nanocarriers

Autores Simões SM, Rey-Rico, A, Concheiro A, Alvarez-Lorenzo C.
Revista CHEM. COMMUN. Vol. 51 Núm. 29 (páxs. 6275 ata 6289)
DOI https://doi.org/10.1039/c4cc10388b

Determination of the Chondrogenic Differentiation Processes in Human Bone Marrow-Derived Mesenchymal Stem Cells Genetically Modified to Overexpress Transforming Growth Factor-beta via Recombinant Adeno-Associated Viral Vectors

Autores Frisch, J, Venkatesan, JK, Rey-Rico, A, Schmitt, G, Madry, H, Cucchiarini, M
Revista HUMAN GENE THERAPY Vol. 25 Núm. 12 (páxs. 1050 ata 1060)
DOI https://doi.org/10.1089/hum.2014.091

Nonviral gene transfer into human meniscal cells. Part II: effect of three-dimensional environment and overexpression of human fibroblast growth factor 2

Autores Lee, HP, Rey-Rico, A, Cucchiarini, M, Madry, H
Revista INTERNATIONAL ORTHOPAEDICS Vol. 38 Núm. 9 (páxs. 1931 ata 1936)
DOI https://doi.org/10.1007/s00264-014-2405-z

Influence of insulin-like growth factor I overexpression via recombinant adeno-associated vector gene transfer upon the biological activities and differentiation potential of human bone marrow-derived mesenchymal stem cells

Autores Frisch, J, Venkatesan, JK, Rey-Rico, A, Schmitt, G, Madry, H, Cucchiarini, M
Revista Stem Cell Research & Therapy Vol. 5
DOI https://doi.org/10.1186/scrt491

Current progress in stem cell-based gene therapy for articular cartilage repair.

Autores Janina Frisch, Jagadeesh K Venkatesan, Rey-Rico, A, Henning Madry, Magali Cucchiarini
Revista Current Stem Cell Research & Therapy Vol. 10 Núm. 2
DOI https://doi.org/10.2174/1574888x09666140922112326

Transforming growth factor Beta-releasing scaffolds for cartilage tissue engineering.

Autores Madry H, Rey-Rico, A, Venkatesan JK, Johnstone B, Cucchiarini M.
Revista Tissue Engineering Part B: Reviews Vol. 20 Núm. 2 (páxs. 106 ata 125)
DOI https://doi.org/10.1089/ten.teb.2013.0271

Current perspectives in stem cell research for knee cartilage repair.

Autores Patrick Orth, Rey-Rico, A, Jagadeesh K Venkatesan, Henning Madry, Magali Cucchiarini
Revista Stem Cells and Cloning Vol. 7 (páxs. 1 ata 17)
DOI https://doi.org/10.2147/sccaa.s42880

Poly(styrene oxide)-poly(ethylene oxide) block copolymers: From ¿classical¿ chemotherapeutic nanocarriers to active cell-response inducers

Autores A. Cambón, Rey-Rico, A, S. Barbosa, J.F.A. Soltero, S.G. Yeates, J. Brea, M.I. Loza, C. Alvarez-Lorenzo, A. Concheiro, P. Taboada, V. Mosquera
Revista JOURNAL OF CONTROLLED RELEASE Vol. 167 Núm. 1 (páxs. 68 ata 75)
DOI https://doi.org/10.1016/j.jconrel.2013.01.010

Doxorubicin-loaded micelles of reverse poly(butylene oxide)-poly(ethylene oxide)-poly(butylene oxide) block copolymers as efficient "active" chemotherapeutic agents

Autores Cambon, A, Rey-Rico, A, Mistry, D, Brea, J, Loza, MI, Attwood, D, Barbosa, S, Alvarez-Lorenzo, C, Concheiro, A, Taboada, P, Mosquera, V
Revista INTERNATIONAL JOURNAL OF PHARMACEUTICS Vol. 445 Núm. 1-2 (páxs. 47 ata 57)
DOI https://doi.org/10.1016/j.ijpharm.2013.01.056

rAAV-mediated overexpression of TGF-beta stably restructures human osteoarthritic articular cartilage in situ

Autores Venkatesan, JK, Rey-Rico, A, Schmitt, G, Wezel, A, Madry, H, Cucchiarini, M
Revista JOURNAL OF TRANSLATIONAL MEDICINE Vol. 11 (páxs. 211 ata 211)
DOI https://doi.org/10.1186/1479-5876-11-211

Poly(ethylene oxide)-poly(styrene oxide)-poly(ethylene oxide) copolymers: Micellization, drug solubilization, and gelling features

Autores Cambon, A, Barbosa, S, Rey-Rico, A, Figueroa-Ochoa, EB, Soltero, JFA, Yeates, SG, Alvarez-Lorenzo, C, Concheiro, A, Taboada, P, Mosquera, V
Revista JOURNAL OF COLLOID AND INTERFACE SCIENCE Vol. 387 (páxs. 275 ata 284)
DOI https://doi.org/10.1016/j.jcis.2012.06.090

Hot melt poly-epsilon-caprolactone/poloxamine implantable matrices for sustained delivery of ciprofloxacin

Autores Puga, AM, Rey-Rico, A, Magarinos, B, Alvarez-Lorenzo, C, Concheiro, A
Revista ACTA BIOMATERIALIA Vol. 8 Núm. 4 (páxs. 1507 ata 1518)
DOI https://doi.org/10.1016/j.actbio.2011.12.020

Wound dressings loaded with an anti-inflammatory jucá (Libidibia ferrea) extract using supercritical carbon dioxide technology

Autores A.M.A.Diasa, Rey-Rico, A, R.A.Oliveiraa, S. Marceneiro, S. Marceneiro, C. Alvarez-Lorenzo, A. Concheiro, R.N.C. Júnior, M.E.M. Braga, H.C. de Sousa
Revista JOURNAL OF SUPERCRITICAL FLUIDS Vol. 74 (páxs. 34 ata 45)
DOI https://doi.org/10.1016/j.supflu.2012.12.007

OSTEOGENIC EFFICIENCY OF IN SITU GELLING POLOXAMINE SYSTEMS WITH AND WITHOUT BONE MORPHOGENETIC PROTEIN-2

Autores Rey-Rico, A, Silva, M, Couceiro, J, Concheiro, A, Alvarez-Lorenzo, C
Revista EUROPEAN CELL & MATERIALS Vol. 21 (páxs. 317 ata 340)
DOI https://doi.org/10.22203/ecm.v021a24

Bio-inspired porous SiC ceramics loaded with vancomycin for preventing MRSA infections

Autores Diaz-Rodriguez, P, Landin, M, Rey-Rico, A, Couceiro, J, Coenye, T, Gonzalez, P, Serra, J, Lopez-Alvarez, M, Leon, B
Revista JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE Vol. 22 Núm. 2 (páxs. 339 ata 347)
DOI https://doi.org/10.1007/s10856-010-4196-0

Inhibition of P-glycoprotein pumps by PEO-PPO amphiphiles: branched versus linear derivatives

Autores Alvarez-Lorenzo, C, Rey-Rico, A, Brea, J, Loza, MI, Concheiro, A, Sosnik, A
Revista NANOMEDICINE Vol. 5 Núm. 9 (páxs. 1371 ata 1383)
DOI https://doi.org/10.2217/nnm.10.53

N-alkylation of poloxamines modulates micellar assembly and encapsulation and release of the antiretroviral efavirenz

Autores Chiappetta, DA, Alvarez-Lorenzo, C, Rey-Rico, A, Taboada, P, Concheiro, A, Sosnik, A
Revista EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS Vol. 76 Núm. 1 (páxs. 24 ata 37)
DOI https://doi.org/10.1016/j.ejpb.2010.05.007

Poloxamine-based nanomaterials for drug delivery.

Autores Alvarez-Lorenzo C, Rey-Rico, A, Sosnik A, Taboada P, Concheiro A
Revista FRONTIERS BIOSCIENCE Vol. 2 (páxs. 424 ata 440)

Mesenchymal stem cells for cartilage repair in osteoarthritis

Autores Rey-Rico, A. Janina Frisch. Magali Cucchiarini
Libro Frontiers in Stem Cell and Regenerative Medicine Research
Vol. 7 Edita Bentham Science Publishers (BSP) .
ISBN: 978-1-68108-553-1
Páxinas Desde a 1 ata a 22

Controlled Gene Delivery Systems for Articular Cartilage Repair

Autores Magali Cucchiarini. Rey-Rico, A
Libro Advances in Biomaterials for Biomedical Applications
Edita Spriger.
ISBN: 1869-8433
Páxinas Desde a 261 ata a 300